Gene: Snx3

Order

Name sorting nexin 3

Synonyms SDP3

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:1860188    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Snx3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Snx3 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal craniofacial morphology Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
abnormal craniofacial morphology Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
abnormal embryo size Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
abnormal embryo size Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 18.5 0.0
abnormal facial morphology Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 18.5 0.0
abnormal forebrain morphology Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
abnormal head shape Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
abnormal head shape Snx3tm1.1(KOMP)Vlcg HOM Female embryonic day 18.5 0.0
abnormal hindbrain morphology Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
abnormal limb morphology Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
abnormal limb morphology Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 18.5 0.0
abnormal midbrain morphology Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
abnormal neural tube closure Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
abnormal tail morphology Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
abnormal tail morphology Snx3tm1.1(KOMP)Vlcg HOM Female embryonic day 18.5 0.0
anophthalmia Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
anophthalmia Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
anophthalmia Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 18.5 0.0
cleft palate Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
edema Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
exencephaly Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
exencephaly Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 18.5 0.0
microphthalmia Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
pallor Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 18.5 0.0
preweaning lethality, complete penetrance Snx3tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
spina bifida Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
syndactyly Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
syndactyly Snx3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 18.5 0.0
decreased leukocyte cell number Snx3tm1.1(KOMP)Vlcg HET Female Male postnatal 2.64E-5
improved glucose tolerance Snx3tm1.1(KOMP)Vlcg HET Female Male postnatal 8.86E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (1/2)
Aorta 2 No (1/562) (2/2)
Bone 2 No (1/539) (2/2)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Epididymis 2 No (4/106) (1/2)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562) (2/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562) (2/2)
Mammary gland 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393) (2/2)
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No (2/2)
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (2/2)
Submandibular gland 2 No (1/104) (2/2)
Testis 2 No (4/562) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562) (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393) (2/2)
Vesicular gland 2 No
White adipose tissue 2 No (2/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    respiratory system endocrine system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system adipose tissue trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/482) (1/2)
Ear 1 (1/482) (1/2)
Embryo 1 (1/482) (1/2)
Eye 1 (1/482) (1/2)
Foot 1 (1/482) (1/2)
Forebrain 1 (1/482) (1/2)
Forelimb 1 (1/482) (1/2)
Hand 1 (1/482) (1/2)
Head 1 (5/482) (1/2)
Heart 1 (1/482) (1/2)
Hindbrain 1 (6/482) (1/2)
Hindlimb 1 (1/482) (1/2)
Liver 1 (1/482) (1/2)
Lung 1 (1/482) (1/2)
Mandibular process 1 (1/482) (1/2)
Maxillary process 1 (1/482) (1/2)
Midbrain 1 (1/482) (1/2)
Oral cavity 1 (1/482) (1/2)
Skin 1 (1/482) (1/2)
Tail 1 (1/482) (1/2)
Tail somite 1 (1/482) (1/2)


Associated Images

Associated Images
  • Gross Morphology Embryo E18.5
    14 Images
  • Embryo LacZ: LacZ images wholemount
    16 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Gross Morphology Embryo E14.5-E15.5
    23 Images
  • X-ray: XRay Images Forepaw
    10 Images
  • Electroretinography 2: Rod and cone PDF
    4 Images
  • Gross Morphology Embryo E12.5
    14 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Snx3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Snx3tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Snx3tm49788(L1L2_Bact_P)
Vector
Gene