Gene: Gtpbp2

Order

Name GTP binding protein 2

Synonyms nmf205

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1860138    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Gtpbp2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Gtpbp2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
enlarged lymph nodes Gtpbp2tm1b(KOMP)Mbp HOM Male postnatal 0.0
enlarged lymph nodes Gtpbp2tm1b(KOMP)Mbp HET Female Male postnatal 0.0
preweaning lethality, incomplete penetrance Gtpbp2tm1b(KOMP)Mbp HOM Female Male n/a 0.0
increased or absent threshold for auditory brainstem response Gtpbp2tm1b(KOMP)Mbp HOM Female Male postnatal 6.47E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Brain 2 No (2/2)
Brainstem 2 No (1/2)
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Esophagus 2 No (7/415)
Eye 2 No (1/2)
Heart 2 No
Hippocampus 2 No (2/2)
Hypothalamus 2 No (1/2)
Kidney 2 No (18/584) (1/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No (1/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Uterus 2 No
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    nervous system
    sensory organ
    reproductive system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    46 Images
  • Adult LacZ: LacZ Images Section
    11 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    23 Images
  • X-ray: XRay Images Dorso Ventral
    23 Images
  • Gross Pathology and Tissue Collection
    16 Images
  • X-ray: XRay Images Hind Leg and Hip
    23 Images
  • Histopathology
    7 Images
  • Eye Morphology: Images Ophthalmoscopy
    26 Images
  • Eye Morphology: Images Slit Lamp
    8 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Gtpbp2tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Gtpbp2tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Gtpbp2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene