Gene: Tmod2

Order

Name tropomodulin 2

Synonyms
  • N-Tmod
  • neural tropomodulin
  • NTMOD

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1355335    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Tmod2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Tmod2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal behavioral response to light Tmod2tm1b(KOMP)Wtsi HOM Female Male postnatal 8.32E-30
abnormal behavior Tmod2tm1b(KOMP)Wtsi HOM Female Male postnatal 2.04E-20
abnormal sleep behavior Tmod2tm1b(KOMP)Wtsi HOM Female Male postnatal 3.04E-7
hyperactivity Tmod2tm1b(KOMP)Wtsi HOM Female Male postnatal 8.8E-7
increased anxiety-related response Tmod2tm1b(KOMP)Wtsi HOM Female Male postnatal 6.42E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (1/2)
Aorta 2 No (1/562) (2/2)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Epididymis 2 No (4/106)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562) (2/2)
Heart 2 No (3/562)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562) (2/2)
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393) (2/2)
Pituitary gland 2 No (1/562) (1/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (2/2)
Submandibular gland 2 No (1/104)
Testis 2 No (4/562) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562)
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393) (2/2)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse endocrine system respiratory system digestive system cardiovascular system nervous system sensory organ reproductive system immune system integumental system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/482) (2/3)
Dorsal root ganglion 2 (1/45) (1/3)
Ear 2 (1/482) (1/3)
Embryo 2 (1/482) (2/3)
Eye 2 (1/482)
Foot 2 (1/482)
Forebrain 2 (1/482) (1/3)
Forelimb 2 (1/482)
Fronto-nasal process 2 (1/46)
Hand 2 (1/482)
Head 2 (5/482) (2/3)
Heart 2 (1/482)
Hindbrain 2 (6/482) (2/3)
Hindlimb 2 (1/482)
Liver 2 (1/482)
Lung 2 (1/482) Image Only
Mandibular process 2 (1/482) (1/3)
Maxillary process 2 (1/482)
Midbrain 2 (1/482) (2/3)
Nose 2 (1/47)
Oral cavity 2 (1/482)
Skin 2 (1/482) Image Only
Spinal cord 2 (1/46) (2/3)
Tail 2 (1/482) (2/3)
Tail somite 2 (1/482)


Associated Images

Associated Images
  • X-ray: XRay Images Forepaw
    9 Images
  • X-ray: XRay Images Skull Lateral Orientation
    9 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    9 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • Sleep Wake: Wake state (bmp file)
    7 Images
  • Eye Morphology: Images Slit Lamp
    3 Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • X-ray: XRay Images Lateral Orientation
    9 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Tmod2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Tmod2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene