Gene: Siva1

Order

Name SIVA1, apoptosis-inducing factor

Synonyms CD27bp

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1353606    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Siva1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Siva1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
cataract Siva1tm1b(EUCOMM)Hmgu HOM Male postnatal 7.46E-9
abnormal lens morphology Siva1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 3.54E-8
decreased heart left ventricle size Siva1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 5.81E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 0 No (5/393)
Aorta 0 No (1/562)
Blood 0 No
Bone 0 No (1/539)
Bone marrow 0 No
Brain 0 Yes (6/562) (2/2)
Brainstem 0 No (4/562)
Brown adipose tissue 0 No
Cartilage tissue 0 No (1/562)
Cecum 0 No (1/355)
Cerebellum 0 No (4/562)
Cerebral cortex 0 No (5/562)
Chest bone 0 No
Colon 0 No (1/99)
Cranium 0 No
Diaphragm 0 No
Epididymis 0 No (4/106)
Esophagus 0 No (2/393)
Eye 0 No (1/562)
Gall bladder 0 No
Harderian gland 0 No
Heart 0 Yes (3/562) (2/2)
Hindlimb 0 No
Hippocampus 0 No (5/562)
Hypothalamus 0 No (4/562)
Kidney 0 Yes (20/562) (2/2)
Large intestine 0 No (12/562)
Liver 0 No
Lower urinary tract 0 No (3/562)
Lung 0 No (3/562)
Lymph node 0 No (1/562)
Main olfactory bulb 0 No
Mammary gland 0 No
Mesenteric lymph node 0 No
Olfactory lobe 0 No (4/393)
Oral epithelium 0 No
Ovary 0 Yes (1/562)
Oviduct 0 No (2/562)
Pancreas 0 No (6/562)
Parathyroid gland 0 No (2/540)
Parotid gland 0 No
Penis 0 No
Peripheral nervous system 0 No (3/562)
Peyer's patch 0 No (1/393)
Pituitary gland 0 Yes (1/562) (2/2)
Prostate gland 0 No (5/562)
Sciatic nerve 0 No
Skeletal muscle 0 No
Skin 0 No (1/562)
Small intestine 0 No (11/562)
Spinal cord 0 Yes (3/562) (2/2)
Spleen 0 No (4/562)
Stomach 0 Yes (9/562) (2/2)
Stomach pyloric region 0 No
Striatum 0 No (4/562)
Sublingual gland 0 No
Submandibular gland 0 Yes (1/104) (1/2)
Testis 0 Yes (4/562) (1/2)
Thymus 0 No
Thyroid gland 0 Yes (16/562) (2/2)
Tongue 0 No
Trachea 0 No (3/562)
Trigeminal V nerve 0 No
Urinary bladder 0 Yes
Uterus 0 Yes (2/562)
Vagina 0 No
Vas deferens 0 Yes (1/360)
Vascular system 0 No (1/393)
Vesicular gland 0 Yes
White adipose tissue 0 Yes (1/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    nervous system
    set of connective tissues
    reproductive system
    adipose tissue
    exocrine system
    trunk
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • Adult LacZ: LacZ Images Wholemount
    19 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Siva1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Siva1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene