Gene: Slco2b1

Order

Name solute carrier organic anion transporter family, member 2b1

Synonyms
  • Slc21a9
  • OATP-B

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1351872    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Slco2b1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Slco2b1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased body weight Slco2b1tm1a(KOMP)Wtsi HOM Female Male postnatal 3.86E-12

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/2)
Aorta 2 No
Blood vessel 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No (2/2)
Lung 2 No
Lymph node 2 No (2/2)
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No (2/2)
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Uterus 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system postnatal mouse digestive system nervous system reproductive system immune system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (14)
  • Slco2b1tm1a(KOMP)Wtsi
    spleen, HET, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    ovary, HET, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    mesenteric lymph node, lymph node, HET, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    peyer's patch, HET, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    small intestine, HET, Female, WTSI

show all 14 images

trunk (9)
  • Slco2b1tm1a(KOMP)Wtsi
    spleen, HET, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    ovary, HET, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    peyer's patch, HET, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    small intestine, HET, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    kidney, HET, Female, WTSI

show all 9 images

immune system (4)
  • Slco2b1tm1a(KOMP)Wtsi
    spleen, HET, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    mesenteric lymph node, lymph node, HET, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    peyer's patch, HET, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    inguinal lymph node, lymph node, HET, Female, WTSI
digestive system (3)
  • Slco2b1tm1a(KOMP)Wtsi
    peyer's patch, HET, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    small intestine, HET, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    large intestine, HET, Female, WTSI
nervous system (3)
  • Slco2b1tm1a(KOMP)Wtsi
    peripheral nervous system, HET, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    brain, HET, Male, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    brain, HET, Male, WTSI
reproductive system (2)
  • Slco2b1tm1a(KOMP)Wtsi
    ovary, HET, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    testis, HET, Male, WTSI
urinary system (2)
  • Slco2b1tm1a(KOMP)Wtsi
    kidney, HET, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
endocrine system (1)
  • Slco2b1tm1a(KOMP)Wtsi
    adrenal gland, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (93)
  • Slco2b1tm1a(KOMP)Wtsi
    head, HOM, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    head, HOM, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    forearm, HOM, Female, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    body, HOM, Male, WTSI
  • Slco2b1tm1a(KOMP)Wtsi
    head, HOM, Male, WTSI

show all 93 images

Skin Histopathology (1)
  • Slco2b1tm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Slco2b1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Slco2b1tm42989(L1L2_gt0)
Vector
Gene