Gene: Amfr

Order

Name autocrine motility factor receptor

Synonyms gp78

Status ES CellsMice
tm1a
Mice
em1
phenotype data available

Links MGI:1345634    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Amfr

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Amfr data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Amfrtm1a(KOMP)Wtsi HOM Female Male n/a 0.0
abnormal behavior Amfrtm1a(KOMP)Wtsi HET Female postnatal 9.28E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/2)
Aorta 2 No
Blood vessel 2 No (1/2)
Bone 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/2)
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No (2/2)
Gall bladder 2 No (1/2)
Heart 2 No (2/2)
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No (1/2)
Lower urinary tract 2 No (2/2)
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No (2/2)
Esophagus 2 No (2/2)
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No (1/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (1/2)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system trunk postnatal mouse nervous system sensory organ exocrine system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (21)
  • Amfrtm1a(KOMP)Wtsi
    pituitary gland, peripheral nervous system, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    brain, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    eye, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    heart, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI

show all 21 images

trunk (13)
  • Amfrtm1a(KOMP)Wtsi
    heart, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    kidney, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    adrenal gland, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    gall bladder, liver, HET, Female, WTSI

show all 13 images

digestive system (4)
  • Amfrtm1a(KOMP)Wtsi
    gall bladder, liver, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    oesophagus, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    large intestine, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    small intestine, HET, Female, WTSI
nervous system (4)
  • Amfrtm1a(KOMP)Wtsi
    pituitary gland, peripheral nervous system, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    brain, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    brain, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    spinal cord, HET, Female, WTSI
cardiovascular system (2)
  • Amfrtm1a(KOMP)Wtsi
    heart, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    blood vessel, HET, Female, WTSI
endocrine system (2)
  • Amfrtm1a(KOMP)Wtsi
    adrenal gland, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    parathyroid gland, HET, Female, WTSI
reproductive system (2)
  • Amfrtm1a(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Amfrtm1a(KOMP)Wtsi
    oviduct, HET, Female, WTSI
sensory organ (2)
  • Amfrtm1a(KOMP)Wtsi
    eye, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    pinna, skin, HET, Female, WTSI
urinary system (2)
  • Amfrtm1a(KOMP)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    kidney, HET, Female, WTSI
integumental system (1)
  • Amfrtm1a(KOMP)Wtsi
    pinna, skin, HET, Female, WTSI
musculoskeletal system (1)
  • Amfrtm1a(KOMP)Wtsi
    bone, HET, Female, WTSI
respiratory system (1)
  • Amfrtm1a(KOMP)Wtsi
    lung, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (166)
  • Amfrtm1a(KOMP)Wtsi
    body, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    head, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    forearm, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    body, HET, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    head, HET, Female, WTSI

show all 166 images

Skin Histopathology (5)
  • Amfrtm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI
  • Amfrtm1a(KOMP)Wtsi
    back skin, HET, Female, WTSI
Eye Morphology (1)
  • Amfrtm1a(KOMP)Wtsi
    eye, abnormal retinal pigmentation, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Amfrtm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Amfrem1(IMPC)Wtsi Exon Deletion
Vector
Gene