Gene: Ikzf3

Order

Name IKAROS family zinc finger 3

Synonyms
  • Zfpn1a3
  • Aiolos
  • 5830411O07Rik

Status ES CellsMice
tm1
phenotype data available

Links MGI:1342542    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Ikzf3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ikzf3 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased lymphocyte cell number Ikzf3tm1(KOMP)Vlcg HOM Female Male postnatal 1.22E-14
decreased leukocyte cell number Ikzf3tm1(KOMP)Vlcg HOM Female Male postnatal 2.32E-14
increased neutrophil cell number Ikzf3tm1(KOMP)Vlcg HOM Female Male postnatal 3.41E-7
increased monocyte cell number Ikzf3tm1(KOMP)Vlcg HOM Female Male postnatal 2.89E-5
decreased large unstained cell number Ikzf3tm1(KOMP)Vlcg HOM Female Male postnatal 8.87E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No (2/415)
Aorta 4 No
Bone 4 Yes
Brain 4 No
Brainstem 4 No
Brown adipose tissue 4 No
Cartilage tissue 4 No
Cecum 4 Yes (12/383)
Cerebellum 4 No
Cerebral cortex 4 No
Chest bone 4 Yes
Colon 4 No (12/127)
Cranium 4 No
Diaphragm 4 No
Duodenum 4 No (2/127)
Epididymis 4 Yes (18/134)
Esophagus 4 No (7/415)
Eye 4 No
Gall bladder 4 Yes
Gonadal fat pad 4 No
Harderian gland 4 Yes
Heart 4 No
Hindlimb 4 No
Hippocampus 4 No
Hypothalamus 4 No
Ileum 4 Yes (14/127)
Jejunum 4 Yes (6/127)
Kidney 4 Yes (18/584) (5/6)
Large intestine 4 Yes (10/584)
Liver 4 No
Lower urinary tract 4 No
Lung 4 No
Lymph node 4 Yes (6/6)
Main olfactory bulb 4 Yes
Mammary gland 4 No
Mesenteric lymph node 4 Yes (6/6)
Mesenteric adipose tissue 4 No
Midbrain 4 No
Olfactory lobe 4 No
Oral epithelium 4 Yes
Ovary 4 Yes (1/584)
Oviduct 4 Yes
Pancreas 4 No (5/584)
Parathyroid gland 4 Yes
Parotid gland 4 Yes
Penis 4 No
Peripheral nervous system 4 No
Peyer's patch 4 Yes (6/6)
Pituitary gland 4 Yes
Prostate gland 4 Yes (12/584)
Quadriceps 4 No
Sciatic nerve 4 No
Skeletal muscle 4 No
Skin 4 No
Small intestine 4 No (9/584)
Spinal cord 4 Yes (6/6)
Spleen 4 Yes (2/584) (6/6)
Stomach 4 Yes (12/584)
Stomach pyloric region 4 No
Striatum 4 No
Sublingual gland 4 Yes
Submandibular gland 4 Yes (2/132)
Testis 4 Yes (2/584) (3/6)
Thalamus 4 No
Thymus 4 No
Thyroid gland 4 Yes (15/584)
Tongue 4 No (5/127)
Trachea 4 No
Trigeminal V nerve 4 No
Urinary bladder 4 Yes
Uterus 4 Yes
Vagina 4 No
Vas deferens 4 No (15/388)
Vascular system 4 No
Vesicular gland 4 Yes
White adipose tissue 4 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    digestive system
    nervous system
    reproductive system
    immune system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 3 (6/485)
Ear 3 (1/485)
Embryo 3 (1/485)
Eye 3 (1/485)
Foot 3 (1/485)
Forearm 3 (1/282)
Forebrain 3 (1/485)
Forelimb 3 (1/485)
Hand 3 (1/485)
Head 3 (5/485)
Heart 3 (1/485)
Hindbrain 3 (6/485)
Hindlimb 3 (1/485)
Liver 3 (1/485)
Lower leg 3 (1/282)
Lung 3 (1/485)
Mandibular process 3 (1/485)
Maxillary process 3 (1/485)
Midbrain 3 (1/485)
Oral cavity 3 (1/485)
Skin 3 (1/485)
Tail 3 (1/485)
Tail somite 3 (1/485)
Upper arm 3 (1/282)
Upper leg 3 (1/282)


Associated Images

Associated Images
  • Adult LacZ: LacZ Images Wholemount
    168 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Embryo LacZ: LacZ images wholemount
    6 Images
  • Eye Morphology: Images Ophthalmoscopy
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ikzf3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Ikzf3tm221089(L1L2_Bact_P)
Vector
Gene