Gene: Cacna2d3

Order

Name calcium channel, voltage-dependent, alpha2/delta subunit 3

Synonyms
  • alpha 2 delta-3
  • alpha2delta3

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1338890    Ensembl Gene    Ensembl Orthologs    My Genes    IDG   

Viability Homozygous - Viable

Phenotype associations for Cacna2d3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cacna2d3 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased circulating glucose level Cacna2d3tm1b(KOMP)Wtsi HET Female Male postnatal 2.18E-6
increased circulating sodium level Cacna2d3tm1b(KOMP)Wtsi HET Female Male postnatal 3.04E-5
decreased circulating free fatty acid level Cacna2d3tm1b(KOMP)Wtsi HET Female Male postnatal 6.41E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No (2/2)
Brain 2 No (1/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415)
Eye 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Midbrain 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No
Spleen 2 No (2/584) (1/2)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Submandibular gland 2 No (2/132) (1/2)
Testis 2 No (2/584) (1/2)
Thalamus 2 No
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system digestive system cardiovascular system nervous system reproductive system immune system exocrine system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485)
Dorsal root ganglion 2 (1/47)
Ear 2 (1/485)
Embryo 2 (1/485) (2/3)
Eye 2 (1/485)
Foot 2 (1/485)
Forebrain 2 (1/485)
Forelimb 2 (1/485)
Fronto-nasal process 2 (1/48)
Hand 2 (1/485)
Head 2 (5/485)
Heart 2 (1/485) (1/3)
Hindbrain 2 (6/485)
Hindlimb 2 (1/485)
Liver 2 (1/485)
Lung 2 (1/485)
Mandibular process 2 (1/485)
Maxillary process 2 (1/485)
Midbrain 2 (1/485)
Nose 2 (1/51)
Oral cavity 2 (1/485)
Skin 2 (1/485)
Spinal cord 2 (1/50)
Tail 2 (1/485)
Tail somite 2 (1/485)


Associated Images

Associated Images
  • Embryo LacZ: LacZ images wholemount
    12 Images
  • X-ray: XRay Images Lateral Orientation
    18 Images
  • X-ray: XRay Images Forepaw
    18 Images
  • X-ray: XRay Images Dorso Ventral
    18 Images
  • X-ray: XRay Images Skull Lateral Orientation
    18 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    18 Images
  • Electroretinography 2: Rod and cone PDF
    2 Images
  • Sleep Wake: Wake state (bmp file)
    3 Images
  • Combined SHIRPA and Dysmorphology
    2 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Cacna2d3tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Cacna2d3tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene