Gene: Tulp3

Order

Name tubby-like protein 3

Synonyms 2310022L06Rik

Status ES CellsMice
tm1a
Mice
tm1b
Mice
tm1c
phenotype data available

Links MGI:1329045    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Tulp3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Tulp3 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
Kidney - organ specific developmental defect Tulp3tm1b(EUCOMM)Hmgu HET Male postnatal 0.0
preweaning lethality, complete penetrance Tulp3tm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
increased total body fat amount Tulp3tm1b(EUCOMM)Hmgu HET Male postnatal 9.46E-8
decreased prepulse inhibition Tulp3tm1b(EUCOMM)Hmgu HET Male postnatal 3.39E-7
impaired glucose tolerance Tulp3tm1b(EUCOMM)Hmgu HET Female Male postnatal 8.23E-7
increased circulating aspartate transaminase level Tulp3tm1b(EUCOMM)Hmgu HET Female Male postnatal 1.85E-5
decreased lean body mass Tulp3tm1b(EUCOMM)Hmgu HET Male postnatal 2.28E-5
decreased fasted circulating glucose level Tulp3tm1b(EUCOMM)Hmgu HET Female postnatal 8.67E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562) (2/2)
Bone 2 No (1/539) (2/2)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562) (2/2)
Gall bladder 2 No (2/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No
Lower urinary tract 2 No (3/562) (2/2)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562)
Mammary gland 2 No
Olfactory lobe 2 No (4/393) (2/2)
Oral epithelium 2 No (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562) (1/2)
Skeletal muscle 2 No (2/2)
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (2/2)
Testis 2 No (4/562) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562) (2/2)
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393) (2/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    musculoskeletal system
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/482) (2/2)
Ear 1 (1/482)
Embryo 1 (1/482) (2/2)
Eye 1 (1/482) (1/2)
Foot 1 (1/482) (1/2)
Forebrain 1 (1/482) (1/2)
Forelimb 1 (1/482) (1/2)
Hand 1 (1/482) (1/2)
Head 1 (5/482) (2/2)
Heart 1 (1/482)
Hindbrain 1 (6/482) (1/2)
Hindlimb 1 (1/482) (1/2)
Liver 1 (1/482)
Lung 1 (1/482)
Mandibular process 1 (1/482)
Maxillary process 1 (1/482)
Midbrain 1 (1/482) (1/2)
Oral cavity 1 (1/482)
Skin 1 (1/482)
Tail 1 (1/482) (2/2)
Tail somite 1 (1/482) (1/2)


Associated Images

Associated Images
  • Adult LacZ: LacZ Images Wholemount
    24 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Echo: M-Mode Images
    32 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    1 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Tulp3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Tulp3tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Tulp3tm1c(EUCOMM)Hmgu Wild type floxed exon (post-Flp)
Vector
Gene
Tulp3tm43124(L1L2_gt2)
Vector
Gene