Gene: Orc1

Order

Name origin recognition complex, subunit 1

Synonyms
  • Orc1l
  • MmORC1

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1328337    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Orc1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Orc1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
embryonic lethality prior to organogenesis Orc1tm1b(KOMP)Wtsi HOM Female Male embryonic day 9.5 0.0
preweaning lethality, complete penetrance Orc1tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
preweaning lethality, complete penetrance Orc1tm1a(KOMP)Wtsi HOM Female Male n/a 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Epididymis 2 No (18/134)
Esophagus 2 No (7/415)
Eye 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Midbrain 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Submandibular gland 2 No (2/132) (1/2)
Testis 2 No (2/584)
Thalamus 2 No
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Urinary bladder 2 No
Uterus 2 No
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    respiratory system postnatal mouse digestive system exocrine system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/485)
Dorsal root ganglion 1 (1/47)
Ear 1 (1/485)
Embryo 1 (1/485)
Eye 1 (1/485)
Foot 1 (1/485)
Forebrain 1 (1/485)
Forelimb 1 (1/485)
Fronto-nasal process 1 (1/48)
Hand 1 (1/485)
Head 1 (5/485)
Heart 1 (1/485)
Hindbrain 1 (6/485)
Hindlimb 1 (1/485)
Liver 1 (1/485)
Lung 1 (1/485)
Mandibular process 1 (1/485)
Maxillary process 1 (1/485)
Midbrain 1 (1/485)
Nose 1 (1/51)
Oral cavity 1 (1/485)
Skin 1 (1/485)
Spinal cord 1 (1/50)
Tail 1 (1/485)
Tail somite 1 (1/485)


Associated Images

Associated Images
  • Electroretinography 2: Rod and cone PDF
    4 Images
  • X-ray: XRay Images Dorso Ventral
    13 Images
  • X-ray: XRay Images Lateral Orientation
    12 Images
  • X-ray: XRay Images Forepaw
    11 Images
  • X-ray: XRay Images Skull Lateral Orientation
    11 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    11 Images
  • Anti-nuclear antibody assay
    6 Images
  • DSS Histology
    8 Images
  • Combined SHIRPA and Dysmorphology
    3 Images
Legacy Phenotype Associated Images
Xray (90)
  • Orc1tm1a(KOMP)Wtsi
    HET, Male, WTSI
  • Orc1tm1a(KOMP)Wtsi
    HET, Male, WTSI
  • Orc1tm1a(KOMP)Wtsi
    HET, Male, WTSI
  • Orc1tm1a(KOMP)Wtsi
    HET, Male, WTSI
  • Orc1tm1a(KOMP)Wtsi
    HET, Male, WTSI

show all 90 images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Orc1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Orc1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Orc1tm295368(L1L2_Bact_P)
Vector
Gene
Orc1tm36556(L1L2_gt1)
Vector
Gene