Gene: Dnajb3

Order

Name DnaJ heat shock protein family (Hsp40) member B3

Synonyms
  • MSJ-1
  • Msj1
  • Hsj3

Status ES CellsMice
tm1.1
Mice
tm1
phenotype data available

Links MGI:1306822    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Dnajb3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Dnajb3 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased bone mineral density Dnajb3tm1.1(KOMP)Vlcg HOM Female postnatal 3.51E-6
decreased bone mineral content Dnajb3tm1.1(KOMP)Vlcg HOM Male postnatal 4.95E-5
increased bone mineral content Dnajb3tm1.1(KOMP)Vlcg HOM Female postnatal 4.95E-5
increased body length Dnajb3tm1.1(KOMP)Vlcg HOM Female postnatal 6.1E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562)
Bone marrow 2 No (1/2)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Epididymis 2 No (4/106) (1/2)
Esophagus 2 No (2/393)
Eye 2 No (1/562) (2/2)
Heart 2 No (3/562)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562)
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562) (1/2)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (2/2)
Submandibular gland 2 No (1/104) (2/2)
Testis 2 No (4/562) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562) (2/2)
Urinary bladder 2 No
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    set of connective tissues
    reproductive system
    musculoskeletal system
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/482) (2/3)
Central nervous system ganglion 1 (1/47) (1/1)
Dorsal root ganglion 2 (1/45) (1/3)
Ear 2 (1/482)
Embryo 2 (1/482) (2/3)
Eye 2 (1/482)
Foot 2 (1/482)
Forebrain 2 (1/482) (1/3)
Forelimb 2 (1/482)
Fronto-nasal process 2 (1/46)
Hand 2 (1/482)
Head 2 (5/482) (2/3)
Heart 2 (1/482)
Hindbrain 2 (6/482) (2/3)
Hindlimb 2 (1/482)
Liver 2 (1/482)
Lung 2 (1/482)
Mandibular process 2 (1/482) (1/3)
Maxillary process 2 (1/482)
Midbrain 2 (1/482) (2/3)
Nose 2 (1/47)
Oral cavity 2 (1/482)
Skin 2 (1/482)
Spinal cord 2 (1/46) (2/3)
Tail 2 (1/482)
Tail somite 2 (1/482)


Associated Images

Associated Images
  • Eye Morphology: Images Slit Lamp
    2 Images
  • X-ray: XRay Images Dorso Ventral
    11 Images
  • X-ray: XRay Images Forepaw
    11 Images
  • X-ray: XRay Images Lateral Orientation
    11 Images
  • Embryo LacZ: LacZ images wholemount
    12 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    11 Images
  • X-ray: XRay Images Skull Lateral Orientation
    11 Images
  • Sleep Wake: Wake state (bmp file)
    7 Images
  • Combined SHIRPA and Dysmorphology
    3 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Dnajb3tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Dnajb3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Dnajb3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene