Gene: D1Ertd622e

Order

Name DNA segment, Chr 1, ERATO Doi 622, expressed

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:1277184    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for D1Ertd622e

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all D1Ertd622e data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance D1Ertd622etm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
increased circulating sodium level D1Ertd622etm1.1(KOMP)Vlcg HET Female Male postnatal 1.05E-6
increased circulating potassium level D1Ertd622etm1.1(KOMP)Vlcg HET Female Male postnatal 1.07E-6
decreased circulating glucose level D1Ertd622etm1.1(KOMP)Vlcg HET Female Male postnatal 5.63E-6
decreased fasted circulating glucose level D1Ertd622etm1.1(KOMP)Vlcg HET Female Male postnatal 3.89E-5
increased circulating chloride level D1Ertd622etm1.1(KOMP)Vlcg HET Female Male postnatal 3.89E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562) (2/2)
Bone marrow 2 No (2/2)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Epididymis 2 No (4/106) (1/2)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562) (2/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562) (2/2)
Mammary gland 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393) (2/2)
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No (2/2)
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (2/2)
Submandibular gland 2 No (1/104) (2/2)
Testis 2 No (4/562) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562) (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393) (2/2)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    musculoskeletal system
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/482) (2/3)
Dorsal root ganglion 0 (1/45) (1/1)
Ear 1 (1/482) (2/3)
Embryo 1 (1/482) (2/3)
Eye 1 (1/482) (2/3)
Foot 1 (1/482) (2/3)
Forebrain 1 (1/482) (2/3)
Forelimb 1 (1/482) (2/3)
Fronto-nasal process 0 (1/46) Image Only
Hand 1 (1/482) (2/3)
Head 1 (5/482) (2/3)
Heart 1 (1/482) (2/3)
Hindbrain 1 (6/482) (2/3)
Hindlimb 1 (1/482) (2/3)
Liver 1 (1/482) (2/3)
Lung 1 (1/482) Image Only
Mandibular process 1 (1/482) (2/3)
Maxillary process 1 (1/482) (2/3)
Midbrain 1 (1/482) (2/3)
Nose 0 (1/47) (1/1)
Oral cavity 1 (1/482) (1/3)
Skin 1 (1/482) (2/3)
Spinal cord 1 (1/46) (2/2)
Tail 1 (1/482) (2/3)
Tail somite 1 (1/482) (2/3)
Umbilical artery embryonic part 1 (1/45) (1/1)
Umbilical vein embryonic part 1 (1/45) (1/1)


Associated Images

Associated Images
  • Eye Morphology: Images Slit Lamp
    2 Images
  • X-ray: XRay Images Forepaw
    9 Images
  • X-ray: XRay Images Lateral Orientation
    9 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    9 Images
  • Electroretinography 2: Rod and cone PDF
    4 Images
  • X-ray: XRay Images Skull Lateral Orientation
    9 Images
  • Sleep Wake: Wake state (bmp file)
    1 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
D1Ertd622etm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
D1Ertd622etm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
D1Ertd622etm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene