Gene: Tmem42

Order

Name transmembrane protein 42

Synonyms
  • 0610027O18Rik
  • D9Ertd662e
  • 4933429E06Rik

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1277176    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Tmem42

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Tmem42 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased bone mineral density Tmem42tm1b(KOMP)Wtsi HOM Male postnatal 3.12E-5
increased lean body mass Tmem42tm1b(KOMP)Wtsi HOM Female Male postnatal 3.17E-5
decreased circulating insulin level Tmem42tm1b(KOMP)Wtsi HOM Male postnatal 9.46E-5
increased circulating insulin level Tmem42tm1b(KOMP)Wtsi HOM Female postnatal 9.46E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No
Blood vessel 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No (2/2)
Hypothalamus 2 No
Kidney 2 No (18/584)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Uterus 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse endocrine system nervous system reproductive system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (5)
  • Tmem42tm1b(KOMP)Wtsi
    parathyroid gland, HET, Female, WTSI
  • Tmem42tm1b(KOMP)Wtsi
    spinal cord, HET, Male, WTSI
  • Tmem42tm1b(KOMP)Wtsi
    striatum, HET, Female, WTSI
  • Tmem42tm1b(KOMP)Wtsi
    pituitary gland, HET, Female, WTSI
  • Tmem42tm1b(KOMP)Wtsi
    testis, HET, Male, WTSI
nervous system (3)
  • Tmem42tm1b(KOMP)Wtsi
    spinal cord, HET, Male, WTSI
  • Tmem42tm1b(KOMP)Wtsi
    striatum, HET, Female, WTSI
  • Tmem42tm1b(KOMP)Wtsi
    pituitary gland, HET, Female, WTSI
trunk (2)
  • Tmem42tm1b(KOMP)Wtsi
    spinal cord, HET, Male, WTSI
  • Tmem42tm1b(KOMP)Wtsi
    testis, HET, Male, WTSI
endocrine system (1)
  • Tmem42tm1b(KOMP)Wtsi
    parathyroid gland, HET, Female, WTSI
reproductive system (1)
  • Tmem42tm1b(KOMP)Wtsi
    testis, HET, Male, WTSI

Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    24 Images
  • X-ray: XRay Images Forepaw
    12 Images
  • X-ray: XRay Images Dorso Ventral
    36 Images
  • X-ray: XRay Images Skull Lateral Orientation
    12 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    12 Images
  • Eye Morphology: Images Slit Lamp
    1 Images
  • Anti-nuclear antibody assay
    6 Images
  • DSS Histology
    8 Images
Legacy Phenotype Associated Images
Xray (60)
  • Tmem42tm1b(KOMP)Wtsi
    HOM, Male, WTSI
  • Tmem42tm1b(KOMP)Wtsi
    HOM, Male, WTSI
  • Tmem42tm1b(KOMP)Wtsi
    HOM, Male, WTSI
  • Tmem42tm1b(KOMP)Wtsi
    HOM, Male, WTSI
  • Tmem42tm1b(KOMP)Wtsi
    HOM, Male, WTSI

show all 60 images

Eye Morphology (1)
  • Tmem42tm1b(KOMP)Wtsi
    corneal vascularization, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Tmem42tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Tmem42tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene