Gene: Prep

Order

Name prolyl endopeptidase

Synonyms
  • Pop
  • D10Wsu136e
  • prolyl oligopeptidase

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1270863    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Prep

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Prep data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
embryonic lethality prior to organogenesis Preptm1b(KOMP)Wtsi HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Preptm1b(KOMP)Wtsi HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Preptm1b(KOMP)Wtsi HOM Female Male n/a 0.0
abnormal behavioral response to light Preptm1b(KOMP)Wtsi HET Female Male postnatal 3.86E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Epididymis 2 No (4/106)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Midbrain 2 No
Olfactory lobe 2 No (4/393)
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Submandibular gland 2 No (1/104)
Testis 2 No (4/562) (1/2)
Thalamus 2 No
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Urinary bladder 2 No
Uterus 2 No (2/562)
Vascular system 2 No (1/393)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    reproductive system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/482)
Ear 1 (1/482)
Embryo 1 (1/482)
Eye 1 (1/482)
Foot 1 (1/482)
Forebrain 1 (1/482)
Forelimb 1 (1/482)
Hand 1 (1/482)
Head 1 (5/482)
Heart 1 (1/482)
Hindbrain 1 (6/482)
Hindlimb 1 (1/482)
Liver 1 (1/482)
Lung 1 (1/482)
Mandibular process 1 (1/482)
Maxillary process 1 (1/482)
Midbrain 1 (1/482)
Oral cavity 1 (1/482)
Skin 1 (1/482)
Tail 1 (1/482)
Tail somite 1 (1/482)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    15 Images
  • X-ray: XRay Images Lateral Orientation
    15 Images
  • X-ray: XRay Images Forepaw
    15 Images
  • X-ray: XRay Images Skull Lateral Orientation
    15 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    15 Images
  • Eye Morphology: Images Slit Lamp
    1 Images
  • Combined SHIRPA and Dysmorphology
    1 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Preptm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Preptm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Preptm96475(L1L2_Bact_P)
Vector
Gene