Gene: Plscr2

Order

Name phospholipid scramblase 2

Synonyms PL scramblase

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1270860    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Plscr2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Plscr2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased food intake Plscr2tm1b(KOMP)Wtsi HOM Male postnatal 2.89E-5
increased caudal vertebrae number Plscr2tm1b(KOMP)Wtsi HOM Female Male postnatal 8.82E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No
Blood vessel 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No (2/2)
Cerebral cortex 2 No
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No (2/2)
Uterus 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system nervous system reproductive system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (8)
  • Plscr2tm1b(KOMP)Wtsi
    trachea, HET, Female, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    oviduct, HET, Female, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    kidney, HET, Female, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    cerebellum, HET, Female, WTSI

show all 8 images

trunk (6)
  • Plscr2tm1b(KOMP)Wtsi
    trachea, HET, Female, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    oviduct, HET, Female, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    kidney, HET, Female, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    lung, HET, Female, WTSI

show all 6 images

nervous system (3)
  • Plscr2tm1b(KOMP)Wtsi
    cerebellum, HET, Female, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    spinal cord, HET, Female, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    brain, HET, Female, WTSI
reproductive system (2)
  • Plscr2tm1b(KOMP)Wtsi
    oviduct, HET, Female, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    testis, HET, Male, WTSI
respiratory system (2)
  • Plscr2tm1b(KOMP)Wtsi
    trachea, HET, Female, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    lung, HET, Female, WTSI
urinary system (1)
  • Plscr2tm1b(KOMP)Wtsi
    kidney, HET, Female, WTSI

Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    42 Images
  • X-ray: XRay Images Forepaw
    14 Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • Eye Morphology: Images Slit Lamp
    1 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • Eye Morphology: Images Ophthalmoscopy
    1 Images
  • Anti-nuclear antibody assay
    6 Images
  • DSS Histology
    8 Images
Legacy Phenotype Associated Images
Xray (85)
  • Plscr2tm1b(KOMP)Wtsi
    HOM, Female, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    HOM, Female, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    HOM, Female, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    HOM, Female, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    HOM, Female, WTSI

show all 85 images

Dysmorphology (8)
  • Plscr2tm1b(KOMP)Wtsi
    hindlimb, polydactylous syndactyly, HOM, Male, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    polydactylous syndactyly, hindlimb, HOM, Male, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    head, abnormal snout morphology, upturned snout, HOM, Male, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    abnormal snout morphology, asymmetric snout, head, HOM, Female, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    abnormal snout morphology, asymmetric snout, head, HOM, Female, WTSI

show all 8 images

Eye Morphology (2)
  • Plscr2tm1b(KOMP)Wtsi
    corneal vascularization, HOM, Female, WTSI
  • Plscr2tm1b(KOMP)Wtsi
    abnormal retinal pigmentation, HOM, Male, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Plscr2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Plscr2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Plscr2tm41869(L1L2_gt1)
Vector
Gene