Gene: Slc6a2
Name solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
Synonyms
- Slc6a5
- norepinephrine transporter
- NET
- NE transporter
Status
ES CellsMice
tm1aMice
tm1bphenotype data available
Links MGI:1270850 Ensembl Gene Ensembl Orthologs
Viability Homozygous - Subviable
Phenotype associations for Slc6a2
All Phenotypes Summary
Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Slc6a2 data for that phenotype.
Embryo Data:
3D Embryo Imaging
Significant Phenotypes
| System | Phenotype | Allele | Zyg | Sex | Life Stage | P Value | Data |
|---|---|---|---|---|---|---|---|
|
|
preweaning lethality, incomplete penetrance | Slc6a2tm1b(EUCOMM)Hmgu | HOM |
|
n/a | 0.0 | |
|
|
small heart | Slc6a2tm1b(EUCOMM)Hmgu | HOM |
|
postnatal | 0.0 | |
|
|
impaired glucose tolerance | Slc6a2tm1b(EUCOMM)Hmgu | HET |
|
postnatal | 7.23E-7 | |
|
|
decreased circulating creatine kinase level | Slc6a2tm1b(EUCOMM)Hmgu | HET |
|
postnatal | 2.01E-5 | |
|
|
increased circulating creatine kinase level | Slc6a2tm1b(EUCOMM)Hmgu | HET |
|
postnatal | 2.01E-5 |
Expression
IMPC lacZ Expression Data
Show expression table
Expression No Expression No Tissue Available Ambiguous
Show Wildtype Expression
| Anatomy | #HET Specimens | HOM Images? | WT Expr | Mutant Expr | Images |
|---|---|---|---|---|---|
| Adrenal gland | 2 | No | (5/393) | ||
| Aorta | 2 | No | (1/562) | ||
| Bone | 2 | No | (1/539) | ||
| Brain | 2 | No | (6/562) | ||
| Brainstem | 2 | No | (4/562) | ||
| Brown adipose tissue | 2 | No | |||
| Cartilage tissue | 2 | No | (1/562) | ||
| Cerebellum | 2 | No | (4/562) | ||
| Cerebral cortex | 2 | No | (5/562) | ||
| Esophagus | 2 | No | (2/393) | ||
| Eye | 2 | No | (1/562) | ||
| Gall bladder | 2 | No | |||
| Heart | 2 | No | (3/562) | ||
| Hippocampus | 2 | No | (5/562) | ||
| Hypothalamus | 2 | No | (4/562) | ||
| Kidney | 2 | No | (20/562) | ||
| Large intestine | 2 | No | (12/562) | ||
| Liver | 2 | No | |||
| Lower urinary tract | 2 | No | (3/562) | ||
| Lung | 2 | No | (3/562) | ||
| Lymph node | 2 | No | (1/562) | ||
| Mammary gland | 2 | No | |||
| Olfactory lobe | 2 | No | (4/393) | ||
| Oral epithelium | 2 | No | |||
| Ovary | 2 | No | (1/562) | ||
| Oviduct | 2 | No | (2/562) | ||
| Pancreas | 2 | No | (6/562) | ||
| Parathyroid gland | 2 | No | (2/540) | ||
| Peripheral nervous system | 2 | No | (3/562) | ||
| Peyer's patch | 2 | No | (1/393) | ||
| Pituitary gland | 2 | No | (1/562) | ||
| Prostate gland | 2 | No | (5/562) | ||
| Skeletal muscle | 2 | No | |||
| Skin | 2 | No | (1/562) | ||
| Small intestine | 2 | No | (11/562) | ||
| Spinal cord | 2 | No | (3/562) | ||
| Spleen | 2 | No | (4/562) | ||
| Stomach | 2 | No | (9/562) | ||
| Striatum | 2 | No | (4/562) | ||
| Testis | 2 | No | (4/562) | (1/2) | |
| Thymus | 2 | No | |||
| Thyroid gland | 2 | No | (16/562) | ||
| Trachea | 2 | No | (3/562) | ||
| Uterus | 2 | No | (2/562) | ||
| Vascular system | 2 | No | (1/393) | ||
| White adipose tissue | 2 | No |
No expression image was found for this adult tab
No expression data was found for this embryo tab
Associated Images
Associated Images
-
Echo: M-Mode Images
44 Images
-
X-ray: XRay Images Lateral Orientation
17 Images
-
X-ray: XRay Images Dorso Ventral
17 Images
-
X-ray: XRay Images Skull Lateral Orientation
2 Images
-
Adult LacZ: LacZ Images Wholemount
1 Images
-
X-ray: XRay Images Skull Dorso Ventral Orientation
15 Images
-
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
3 Images
Order Mouse and ES Cells
| Targeting Detail | Product Ordering | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MGI Allele | Allele Type | Type Map Seq | Vector | ES Cell | Mouse | Tissue Enquiry | ||||||
| Slc6a2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) |
|
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| Slc6a2tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (post-Cre) |
|
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