Gene: Slc6a2

Name solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

Synonyms
  • Slc6a5
  • norepinephrine transporter
  • NET
  • NE transporter

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1270850   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Subviable

Phenotype associations for Slc6a2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Slc6a2 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Slc6a2tm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
small heart Slc6a2tm1b(EUCOMM)Hmgu HOM Female postnatal 0.0
impaired glucose tolerance Slc6a2tm1b(EUCOMM)Hmgu HET Male postnatal 7.23E-7
decreased circulating creatine kinase level Slc6a2tm1b(EUCOMM)Hmgu HET Female postnatal 2.01E-5
increased circulating creatine kinase level Slc6a2tm1b(EUCOMM)Hmgu HET Male postnatal 2.01E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Bone 2 No (1/539)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Olfactory lobe 2 No (4/393)
Oral epithelium 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
Vascular system 2 No (1/393)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    reproductive system
    trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • Echo: M-Mode Images
    44 Images
  • X-ray: XRay Images Lateral Orientation
    17 Images
  • X-ray: XRay Images Dorso Ventral
    17 Images
  • X-ray: XRay Images Skull Lateral Orientation
    2 Images
  • Adult LacZ: LacZ Images Wholemount
    1 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    15 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    3 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Slc6a2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Slc6a2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene