Gene: Myo15

Order

Name myosin XV

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1261811    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Myo15

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Myo15 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
absent pinna reflex Myo15tm1a(EUCOMM)Wtsi HOM Female Male postnatal 4.56E-18
abnormal lens morphology Myo15tm1a(EUCOMM)Wtsi HOM Female postnatal 4.31E-6
cataract Myo15tm1a(EUCOMM)Wtsi HOM Female postnatal 4.31E-6
increased grip strength Myo15tm1a(EUCOMM)Wtsi HOM Female postnatal 3.85E-5
increased total body fat amount Myo15tm1a(EUCOMM)Wtsi HOM Female Male postnatal 7.05E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No
Blood vessel 2 No
Bone 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No (1/2)
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Uterus 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse nervous system reproductive system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (2)
  • Myo15tm1a(EUCOMM)Wtsi
    pituitary gland, HET, Female, WTSI
  • Myo15tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
nervous system (1)
  • Myo15tm1a(EUCOMM)Wtsi
    pituitary gland, HET, Female, WTSI
reproductive system (1)
  • Myo15tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
trunk (1)
  • Myo15tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI

Associated Images

Associated Images
  • X-ray: XRay Images Skull Lateral Orientation
    13 Images
  • X-ray: XRay Images Forepaw
    13 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    13 Images
  • X-ray: XRay Images Lateral Orientation
    27 Images
  • X-ray: XRay Images Dorso Ventral
    40 Images
Legacy Phenotype Associated Images
Xray (128)
  • Myo15tm1a(EUCOMM)Wtsi
    head, WT, Male, WTSI
  • Myo15tm1a(EUCOMM)Wtsi
    forearm, WT, Male, WTSI
  • Myo15tm1a(EUCOMM)Wtsi
    head, WT, Male, WTSI
  • Myo15tm1a(EUCOMM)Wtsi
    body, WT, Male, WTSI
  • Myo15tm1a(EUCOMM)Wtsi
    body, WT, Male, WTSI

show all 128 images

Eye Morphology (2)
  • Myo15tm1a(EUCOMM)Wtsi
    persistence of hyaloid vascular system, HOM, Female, WTSI
  • Myo15tm1a(EUCOMM)Wtsi
    left eye, HOM, Female, WTSI
Skin Histopathology (1)
  • Myo15tm1a(EUCOMM)Wtsi
    back skin, HOM, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Myo15tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene