Gene: Kif5a

Order

Name kinesin family member 5A

Synonyms
  • D10Bwg0738e
  • Khc
  • Kns
  • Kif5

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:109564    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Kif5a

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Kif5a data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Kif5atm1b(EUCOMM)Wtsi HET Female Male embryonic day 18.5 0.0
cyanosis Kif5atm1b(EUCOMM)Wtsi HOM Female Male embryonic day 18.5 0.0
preweaning lethality, complete penetrance Kif5atm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
impaired pupillary reflex Kif5atm1b(EUCOMM)Wtsi HET Female Male postnatal 2.34E-10

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Epididymis 2 No (18/134)
Esophagus 2 No (7/415)
Eye 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Midbrain 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No
Pancreas 2 No (5/584)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Submandibular gland 2 No (2/132)
Testis 2 No (2/584) (1/2)
Thalamus 2 No
Thymus 2 No
Thyroid gland 2 No (15/584) (1/2)
Trachea 2 No
Urinary bladder 2 No
Uterus 2 No
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    endocrine system
    digestive system
    reproductive system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485)
Dorsal root ganglion 2 (1/47)
Ear 2 (1/485)
Embryo 2 (1/485)
Eye 2 (1/485)
Foot 2 (1/485)
Forebrain 2 (1/485)
Forelimb 2 (1/485)
Fronto-nasal process 2 (1/48)
Hand 2 (1/485)
Head 2 (5/485)
Heart 2 (1/485)
Hindbrain 2 (6/485)
Hindlimb 2 (1/485)
Liver 2 (1/485)
Lung 2 (1/485)
Mandibular process 2 (1/485)
Maxillary process 2 (1/485)
Midbrain 2 (1/485)
Nose 2 (1/51)
Oral cavity 2 (1/485)
Skin 2 (1/485)
Spinal cord 2 (1/50)
Tail 2 (1/485)
Tail somite 2 (1/485)


Associated Images

Associated Images
  • Sleep Wake: Wake state (bmp file)
    10 Images
  • Gross Morphology Embryo E18.5
    8 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Kif5atm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Kif5atm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene