Gene: Eif4g2

Order

Name eukaryotic translation initiation factor 4, gamma 2

Synonyms
  • DAP-5
  • Natm1
  • Nat1
  • E130105L11Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:109207    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Eif4g2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Eif4g2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
embryonic lethality prior to organogenesis Eif4g2tm1b(KOMP)Wtsi HOM Female Male embryonic day 9.5 0.0
preweaning lethality, complete penetrance Eif4g2tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
decreased circulating chloride level Eif4g2tm1b(KOMP)Wtsi HET Female Male postnatal 4.47E-7
decreased bone mineral density Eif4g2tm1b(KOMP)Wtsi HET Female Male postnatal 6.16E-6
decreased body length Eif4g2tm1b(KOMP)Wtsi HET Female Male postnatal 1.3E-5
increased circulating alkaline phosphatase level Eif4g2tm1b(KOMP)Wtsi HET Female Male postnatal 1.74E-5
hyperactivity Eif4g2tm1b(KOMP)Wtsi HET Female Male postnatal 2.05E-5
increased fasted circulating glucose level Eif4g2tm1b(KOMP)Wtsi HET Female postnatal 3.34E-5
decreased lean body mass Eif4g2tm1b(KOMP)Wtsi HET Female Male postnatal 5.21E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Epididymis 2 No (18/134)
Esophagus 2 No (7/415)
Eye 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (1/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Midbrain 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584)
Striatum 2 No
Submandibular gland 2 No (2/132)
Testis 2 No (2/584)
Thalamus 2 No
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Urinary bladder 2 No
Uterus 2 No
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    cardiovascular system
    sensory organ
    immune system
    trunk
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Forepaw
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Electroretinography 2: Rod and cone PDF
    5 Images
  • Combined SHIRPA and Dysmorphology
    2 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Eif4g2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Eif4g2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Eif4g2tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene