Gene: Atr

Order

Name ataxia telangiectasia and Rad3 related

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:108028    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Atr

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Atr data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal spinal cord morphology Atrtm1b(KOMP)Wtsi HET Female postnatal 0.0
embryonic lethality prior to tooth bud stage Atrtm1b(KOMP)Wtsi HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Atrtm1b(KOMP)Wtsi HOM Female Male n/a 0.0
decreased circulating glucose level Atrtm1b(KOMP)Wtsi HET Female Male postnatal 2.99E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No (2/2)
Cerebral cortex 2 No
Epididymis 2 No (18/134)
Esophagus 2 No (7/415)
Eye 2 No (2/2)
Heart 2 No (1/2)
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (1/2)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Submandibular gland 2 No (2/132) (2/2)
Testis 2 No (2/584) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vas deferens 1 No (15/388)
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system digestive system cardiovascular system nervous system sensory organ reproductive system immune system exocrine system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/485)
Ear 1 (1/485)
Embryo 1 (1/485)
Eye 1 (1/485)
Foot 1 (1/485)
Forebrain 1 (1/485)
Forelimb 1 (1/485)
Hand 1 (1/485)
Head 1 (5/485)
Heart 1 (1/485)
Hindbrain 1 (6/485)
Hindlimb 1 (1/485)
Liver 1 (1/485)
Lung 1 (1/485)
Mandibular process 1 (1/485)
Maxillary process 1 (1/485)
Midbrain 1 (1/485)
Oral cavity 1 (1/485)
Skin 1 (1/485)
Tail 1 (1/485)
Tail somite 1 (1/485)


Associated Images

Associated Images
  • Sleep Wake: Wake state (bmp file)
    11 Images
  • Electroretinography: Cone waveform (pdf format)
    4 Images
  • Combined SHIRPA and Dysmorphology
    2 Images
  • Electroretinography: Rod waveform (pdf format)
    4 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Atrtm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Atrtm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene