Gene: Kif3c

Name kinesin family member 3C

Synonyms N-4 kinesin

Status ES CellsMice
tm1.1
Mice
tm1
phenotype data available

Links MGI:107979   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Lethal

Phenotype associations for Kif3c

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Kif3c data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
prenatal lethality prior to heart atrial septation Kif3ctm1.1(KOMP)Vlcg HOM Female Male embryonic day 14.5 0.0
preweaning lethality, complete penetrance Kif3ctm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
hyperactivity Kif3ctm1.1(KOMP)Vlcg HET Female postnatal 1.14E-11
decreased startle reflex Kif3ctm1.1(KOMP)Vlcg HET Female Male postnatal 3.67E-7
abnormal sleep behavior Kif3ctm1.1(KOMP)Vlcg HET Female Male postnatal 3.13E-5
abnormal behavior Kif3ctm1.1(KOMP)Vlcg HET Female postnatal 8.58E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562) (2/2)
Brain 2 No (5/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Epididymis 2 No (4/106) (1/2)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562) (2/2)
Heart 2 No (3/562)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (19/562) (1/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562)
Mammary gland 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (2/2)
Submandibular gland 2 No (1/104)
Testis 2 No (3/562) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562) (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393) (2/2)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (5/439) (2/3)
Central nervous system ganglion 1 Image Only (1/1)
Dorsal root ganglion 1 Image Only (1/1)
Ear 2
Embryo 2 (2/3)
Eye 2 (2/3)
Foot 2 (1/3)
Forebrain 2 (2/3)
Forelimb 2 (1/3)
Fronto-nasal process 1 Image Only
Hand 2 (1/3)
Head 2 (4/439) (2/3)
Heart 2 (1/3)
Hindbrain 2 (5/439) (2/3)
Hindlimb 2 (1/3)
Liver 2
Lung 2 Image Only
Mandibular process 2 (2/3)
Maxillary process 2 (2/3)
Midbrain 2 (2/3)
Nose 1 Image Only
Oral cavity 2 (1/3)
Skin 2 (1/3)
Spinal cord 1 Image Only (1/1)
Tail 2 (2/3)
Tail somite 2 (1/3)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • X-ray: XRay Images Lateral Orientation
    9 Images
  • X-ray: XRay Images Forepaw
    9 Images
  • X-ray: XRay Images Skull Lateral Orientation
    9 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    9 Images
  • Sleep Wake: Wake state (bmp file)
    10 Images
  • Electroretinography 2: Rod and cone PDF
    2 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Kif3ctm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Kif3ctm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene