Gene: Lrig1

Order

Name leucine-rich repeats and immunoglobulin-like domains 1

Synonyms
  • LIG-1
  • Img

Status ES CellsMice
tm1a
phenotype data available

Links MGI:107935    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Lrig1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Lrig1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal skin condition Lrig1tm1a(EUCOMM)Wtsi HOM Female Male postnatal 0.0
abnormal behavior Lrig1tm1a(EUCOMM)Wtsi HOM Male postnatal 4.32E-6
abnormal tail morphology Lrig1tm1a(EUCOMM)Wtsi HOM Female postnatal 1.13E-5
increased heart weight Lrig1tm1a(EUCOMM)Wtsi HOM Male postnatal 4.42E-5
decreased body weight Lrig1tm1a(EUCOMM)Wtsi HOM Male postnatal 7.82E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No
Blood vessel 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No (1/2)
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No (2/2)
Gall bladder 2 No (1/2)
Heart 2 No (2/2)
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No (2/2)
Esophagus 2 No (1/2)
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (1/2)
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No (1/2)
Thyroid gland 2 No (15/584) (1/2)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
White adipose tissue 2 No (1/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    respiratory system endocrine system digestive system cardiovascular system set of connective tissues reproductive system adipose tissue trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (23)
  • Lrig1tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    peyer's patch, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    skin, inguinal fat pad, mammary gland, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    ovary, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    skin, tail, HET, Female, WTSI

show all 23 images

trunk (12)
  • Lrig1tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    peyer's patch, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    ovary, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    kidney, HET, Male, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    oesophagus, HET, Female, WTSI

show all 12 images

digestive system (4)
  • Lrig1tm1a(EUCOMM)Wtsi
    peyer's patch, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    oesophagus, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    gall bladder, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI
integumental system (4)
  • Lrig1tm1a(EUCOMM)Wtsi
    skin, inguinal fat pad, mammary gland, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    skin, tail, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    pinna, skin, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    skin, HET, Female, WTSI
nervous system (4)
  • Lrig1tm1a(EUCOMM)Wtsi
    brain, HET, Male, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    pituitary gland, peripheral nervous system, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    brain, HET, Male, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    spinal cord, HET, Male, WTSI
adipose tissue (3)
  • Lrig1tm1a(EUCOMM)Wtsi
    skin, inguinal fat pad, mammary gland, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    brown adipose tissue, HET, Male, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    white adipose tissue, HET, Male, WTSI
immune system (3)
  • Lrig1tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    peyer's patch, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    lymph node, HET, Male, WTSI
set of connective tissues (3)
  • Lrig1tm1a(EUCOMM)Wtsi
    skin, inguinal fat pad, mammary gland, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    brown adipose tissue, HET, Male, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    white adipose tissue, HET, Male, WTSI
reproductive system (2)
  • Lrig1tm1a(EUCOMM)Wtsi
    ovary, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
respiratory system (2)
  • Lrig1tm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    thyroid gland, trachea, HET, Male, WTSI
sensory organ (2)
  • Lrig1tm1a(EUCOMM)Wtsi
    eye, HET, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    pinna, skin, HET, Female, WTSI
cardiovascular system (1)
  • Lrig1tm1a(EUCOMM)Wtsi
    heart, HET, Female, WTSI
endocrine system (1)
  • Lrig1tm1a(EUCOMM)Wtsi
    thyroid gland, trachea, HET, Male, WTSI
exocrine system (1)
  • Lrig1tm1a(EUCOMM)Wtsi
    skin, inguinal fat pad, mammary gland, HET, Female, WTSI
urinary system (1)
  • Lrig1tm1a(EUCOMM)Wtsi
    kidney, HET, Male, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (50)
  • Lrig1tm1a(EUCOMM)Wtsi
    forearm, WT, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    body, WT, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    forearm, HOM, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    body, HOM, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    body, HOM, Female, WTSI

show all 50 images

Tail Epidermis Wholemount (6)
  • Lrig1tm1a(EUCOMM)Wtsi
    distorted hair follicle pattern, HOM, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    distorted hair follicle pattern, HOM, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    distorted hair follicle pattern, HOM, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    distorted hair follicle pattern, HOM, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    distorted hair follicle pattern, HOM, Female, WTSI

show all 6 images

Skin Histopathology (3)
  • Lrig1tm1a(EUCOMM)Wtsi
    back skin, HOM, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    back skin, HOM, Female, WTSI
  • Lrig1tm1a(EUCOMM)Wtsi
    back skin, HOM, Female, WTSI
Eye Morphology (1)
  • Lrig1tm1a(EUCOMM)Wtsi
    eye, persistence of hyaloid vascular system, abnormal retinal pigmentation, HOM, Male, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Lrig1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Lrig1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Lrig1tm42916(L1L2_gt2_Del_LacZ)
Vector
Gene
Lrig1tm42916(pL1L2_frt15_BetactinBSD_frt14_neo_Rox)
Vector
Gene