Gene: Hoxb13

Phenotype associations for Hoxb13

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Hoxb13 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal craniofacial morphology Hoxb13tm1b(KOMP)Wtsi HOM Female embryonic day 12.5 0.0
abnormal eye morphology Hoxb13tm1b(KOMP)Wtsi HOM Female embryonic day 12.5 0.0
anophthalmia Hoxb13tm1b(KOMP)Wtsi HOM Female embryonic day 12.5 0.0
microphthalmia Hoxb13tm1b(KOMP)Wtsi HOM Female embryonic day 12.5 0.0
preweaning lethality, incomplete penetrance Hoxb13tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
unresponsive to tactile stimuli Hoxb13tm1b(KOMP)Wtsi HOM Female Male embryonic day 18.5 0.0
unresponsive to tactile stimuli Hoxb13tm1b(KOMP)Wtsi HET Female Male embryonic day 18.5 0.0
increased or absent threshold for auditory brainstem response Hoxb13tm1b(KOMP)Wtsi HOM Female Male postnatal 1.02E-5
increased caudal vertebrae number Hoxb13tm1b(KOMP)Wtsi HOM Female Male postnatal 1.28E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Bone 2 No (1/539)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cecum 2 No (1/355)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562) (2/2)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Mesenteric lymph node 2 No
Olfactory lobe 2 No (4/393)
Oral epithelium 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562) (1/2)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Trigeminal V nerve 2 No
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562)
Vas deferens 2 No (1/360) (1/2)
Vascular system 2 No (1/393)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    reproductive system
    exocrine system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2 (1/3)
Axial skeleton 2 (1/5)
Brain 2 (6/440)
Central nervous system ganglion 2 (1/5)
Cranium 2 Image Only
Dorsal root ganglion 2 (1/3)
Ear 2 (1/440)
Embryo 2 (1/440) (2/2)
Outer ear 2
Eye 2 (1/440)
Femur pre-cartilage condensation 2 Image Only
Foot 2
Forearm 2
Forebrain 2 (1/440)
Forelimb 2 (1/440)
Fronto-nasal process 2 (1/4)
Gut 2 (1/4)
Hand 2
Head 2 (5/440)
Head mesenchyme 2 (1/3)
Heart 2 (1/440)
Heart ventricle 2 (1/3)
Hindbrain 2 (5/440)
Hindlimb 2 (1/440)
Humerus pre-cartilage condensation 2 Image Only
Inner ear 2 Image Only
Intestine 2
Liver 2 (1/440)
Lower leg 2
Lung 2 (1/440)
Mandibular process 2 (1/440)
Maxillary process 2 (1/440)
Mesonephros of female 2 Image Only
Mesonephros of male 2 Image Only
Metanephros 2 Image Only
Midbrain 2 (1/440)
Nasal septum 2
Nose 2 (1/5)
Notochord 2 (2/2)
Oral cavity 2 (1/440)
Outflow tract 2 (1/3)
Pancreas 2 Image Only
Pericardium 2 (1/2)
Pharynx 2 Image Only
Radius-ulna pre-cartilage condensation 2 Image Only
Rib pre-cartilage condensation 2 (1/2)
Skeleton 2 (1/5)
Skin 2 (1/440)
Spinal cord 2 (1/4) (2/2)
Stomach 2 Image Only
Tail 2 (1/440) (2/2)
Tail somite 2 (1/440) (2/2)
Thoracic vertebral cartilage condensation 2 (1/2)
Tongue 2 Image Only
Trachea 2 Image Only
Trunk mesenchyme 2 (1/3)
Umbilical artery embryonic part 2
Umbilical vein embryonic part 2
Upper arm 2
Upper leg 2
Urinary system 2 Image Only
Vibrissa 2


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Lateral Orientation
    11 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Forepaw
    11 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Adult LacZ: LacZ Images Wholemount
    2 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Hoxb13tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Hoxb13tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Hoxb13tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene