Gene: Kcnj11

Name potassium inwardly rectifying channel, subfamily J, member 11

Synonyms Kir6.2

Status ES CellsMice
tm1b
Mice
tm1c
Mice
tm1a
phenotype data available

Links MGI:107501   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Kcnj11

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Kcnj11 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased fasted circulating glucose level Kcnj11tm1b(EUCOMM)Wtsi HOM Female Male postnatal 3.46E-9
impaired glucose tolerance Kcnj11tm1b(EUCOMM)Wtsi HOM Female Male postnatal 3.33E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562) (2/2)
Bone 2 No (1/539)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562)
Large intestine 2 No (12/562) (2/2)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562)
Mammary gland 2 No
Olfactory lobe 2 No (4/393) (2/2)
Oral epithelium 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562) (2/2)
Parathyroid gland 2 No (2/540) (2/2)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562) (1/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No (1/2)
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (2/2)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
Vascular system 2 No (1/393) (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    nervous system
    reproductive system
    musculoskeletal system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/440) (1/4)
Ear 2 (1/440)
Embryo 2 (1/440) (4/4)
Eye 2 (1/440) (2/4)
Foot 2
Forebrain 2 (1/440)
Forelimb 2 (1/440)
Hand 2
Head 2 (5/440) (2/4)
Heart 2 (1/440) (1/4)
Hindbrain 2 (5/440) (1/4)
Hindlimb 2 (1/440)
Liver 2 (1/440)
Lung 2 (1/440)
Mandibular process 2 (1/440)
Maxillary process 2 (1/440)
Midbrain 2 (1/440)
Oral cavity 2 (1/440)
Skin 2 (1/440)
Tail 2 (1/440)
Tail somite 2 (1/440)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    9 Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    9 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • Adult LacZ: LacZ Images Wholemount
    14 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Kcnj11tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Kcnj11tm1c(EUCOMM)Wtsi Wild type floxed exon (post-Flp)
Vector
Gene
Kcnj11tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene