Gene: Ubp1

Name upstream binding protein 1

Synonyms
  • LBP-1b
  • NF2d9
  • LBP-1a

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:104889   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Lethal

Phenotype associations for Ubp1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ubp1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
embryonic lethality prior to tooth bud stage Ubp1tm1b(KOMP)Mbp HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Ubp1tm1b(KOMP)Mbp HOM Female Male n/a 0.0
increased or absent threshold for auditory brainstem response Ubp1tm1b(KOMP)Mbp HET Male postnatal 5.45E-9
decreased lean body mass Ubp1tm1b(KOMP)Mbp HET Male postnatal 4.71E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562) (2/2)
Bone 2 No (1/539) (2/2)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562) (2/2)
Cecum 2 No (1/355)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562) (2/2)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Mesenteric lymph node 2 No
Olfactory lobe 2 No (4/393)
Oral epithelium 2 No
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (2/2)
Parathyroid gland 2 No (2/540) (2/2)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562) (2/2)
Trigeminal V nerve 2 No
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562)
Vas deferens 2 No (1/360)
Vascular system 2 No (1/393)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    respiratory system
    endocrine system
    cardiovascular system
    set of connective tissues
    reproductive system
    musculoskeletal system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2 (1/3) (2/2)
Axial skeleton 2 (1/5) (2/2)
Brain 2 (6/440) (2/2)
Central nervous system ganglion 2 (1/5) (2/2)
Cranium 2 Image Only (2/2)
Dorsal root ganglion 2 (1/3) (2/2)
Ear 2 (1/440) (2/2)
Embryo 2 (1/440) (2/2)
Outer ear 2 (2/2)
Eye 2 (1/440) (2/2)
Femur pre-cartilage condensation 2 Image Only (2/2)
Foot 2 (2/2)
Forearm 2 (2/2)
Forebrain 2 (1/440) (2/2)
Forelimb 2 (1/440) (2/2)
Fronto-nasal process 2 (1/4) (2/2)
Gut 2 (1/4) (2/2)
Hand 2 (2/2)
Head 2 (5/440) (2/2)
Head mesenchyme 2 (1/3) (2/2)
Heart 2 (1/440) (2/2)
Heart ventricle 2 (1/3) (2/2)
Hindbrain 2 (5/440) (2/2)
Hindlimb 2 (1/440) (2/2)
Humerus pre-cartilage condensation 2 Image Only (2/2)
Inner ear 2 Image Only (2/2)
Intestine 2 (2/2)
Liver 2 (1/440) (2/2)
Lower leg 2 (2/2)
Lung 2 (1/440) (2/2)
Mandibular process 2 (1/440) (2/2)
Maxillary process 2 (1/440) (2/2)
Mesonephros of female 2 Image Only (1/2)
Mesonephros of male 2 Image Only (1/2)
Metanephros 2 Image Only (2/2)
Midbrain 2 (1/440) (2/2)
Nasal septum 2 (2/2)
Nose 2 (1/5) (2/2)
Notochord 2 (2/2)
Oral cavity 2 (1/440) (2/2)
Outflow tract 2 (1/3) (2/2)
Pancreas 2 Image Only (2/2)
Pericardium 2 (1/2) (2/2)
Pharynx 2 Image Only (2/2)
Radius-ulna pre-cartilage condensation 2 Image Only (2/2)
Rib pre-cartilage condensation 2 (1/2) (2/2)
Skeleton 2 (1/5) (2/2)
Skin 2 (1/440) (2/2)
Spinal cord 2 (1/4) (2/2)
Stomach 2 Image Only (2/2)
Tail 2 (1/440) (2/2)
Tail somite 2 (1/440) (2/2)
Thoracic vertebral cartilage condensation 2 (1/2) (2/2)
Tongue 2 Image Only (2/2)
Trachea 2 Image Only (2/2)
Trunk mesenchyme 2 (1/3) (2/2)
Umbilical artery embryonic part 2 (2/2)
Umbilical vein embryonic part 2 (2/2)
Upper arm 2 (2/2)
Upper leg 2 (2/2)
Urinary system 2 Image Only (2/2)
Vibrissa 2 (2/2)


Associated Images

Associated Images
  • X-ray: XRay Images Forepaw
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • Adult LacZ: LacZ Images Wholemount
    9 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ubp1tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Ubp1tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene