Gene: Akt2

Order

Name thymoma viral proto-oncogene 2

Synonyms
  • PKB
  • PKBbeta
  • 2410016A19Rik

Status ES Cellsphenotype data available

Links MGI:104874    Ensembl Gene    Ensembl Orthologs    My Genes   

Phenotype associations for Akt2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Akt2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased body weight Akt2tm1Wcs HOM Female Male postnatal 0.0
increased lean body mass Akt2tm1Wcs HOM Female Male postnatal 1.34E-23
increased total body fat amount Akt2tm1Wcs HOM Female Male postnatal 1.74E-23
decreased body weight Akt2tm1Wcs HET Female postnatal 1.82E-21
abnormal bone mineralization Akt2tm1Wcs HOM Female Male postnatal 4.9E-17
decreased lean body mass Akt2tm1Wcs HOM Female Male postnatal 2.64E-15
decreased body length Akt2tm1Wcs HOM Female Male postnatal 2.35E-11
decreased circulating triglyceride level Akt2tm1Wcs HOM Male postnatal 3.67E-11
abnormal glucose homeostasis Akt2tm1Wcs HOM Female postnatal 4.66E-9
decreased bone mineral density Akt2tm1Wcs HOM Female Male postnatal 6.38E-8
thrombocytosis Akt2tm1Wcs HOM Female Male postnatal 8.08E-7
increased circulating alkaline phosphatase level Akt2tm1Wcs HOM Female Male postnatal 9.1E-7
decreased circulating LDL cholesterol level Akt2tm1Wcs HOM Male postnatal 1.79E-6
increased circulating LDL cholesterol level Akt2tm1Wcs HOM Female postnatal 1.79E-6
increased total body fat amount Akt2tm1Wcs HET Female postnatal 6.52E-6
increased lean body mass Akt2tm1Wcs HET Female postnatal 8.81E-6
decreased grip strength Akt2tm1Wcs HOM Female Male postnatal 2.11E-5
decreased circulating cholesterol level Akt2tm1Wcs HOM Male postnatal 4.08E-5
increased circulating cholesterol level Akt2tm1Wcs HOM Female postnatal 4.08E-5
decreased lean body mass Akt2tm1Wcs HET Female postnatal 6.46E-5

Download data as: TSV XLS



Expression

Secondary lacZ Expression Data
trunk (12)
  • Akt2tm1e(KOMP)Wtsi
    TRACHEA, HET, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    LUNG, HET, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    GALL BLADDER, HET, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    ESOPHAGUS, HET, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    SMALL INTESTINE, HET, Female, WTSI

show all 12 images

digestive system (5)
  • Akt2tm1e(KOMP)Wtsi
    GALL BLADDER, HET, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    ESOPHAGUS, HET, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    SMALL INTESTINE, HET, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    SMALL INTESTINE, HET, Male, WTSI
  • Akt2tm1e(KOMP)Wtsi
    LARGE INTESTINE, HET, Female, WTSI
nervous system (3)
  • Akt2tm1e(KOMP)Wtsi
    PITUITARY GLAND, PERIPHERAL NERVOUS SYSTEM, HET, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    BRAIN, HET, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    SPINAL CORD, HET, Female, WTSI
adipose tissue (2)
  • Akt2tm1e(KOMP)Wtsi
    BROWN ADIPOSE TISSUE, HET, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    WHITE ADIPOSE TISSUE, HET, Female, WTSI
endocrine system (2)
  • Akt2tm1e(KOMP)Wtsi
    ADRENAL GLAND, HET, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    PARATHYROID GLAND, HET, Female, WTSI
immune system (2)
  • Akt2tm1e(KOMP)Wtsi
    LYMPH NODE, HET, Male, WTSI
  • Akt2tm1e(KOMP)Wtsi
    SPLEEN, HET, Male, WTSI
musculoskeletal system (2)
  • Akt2tm1e(KOMP)Wtsi
    BONE, HET, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    SKELETAL MUSCLE TISSUE, HET, Female, WTSI
reproductive system (2)
  • Akt2tm1e(KOMP)Wtsi
    UTERUS, HET, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    TESTIS, HET, Male, WTSI
respiratory system (2)
  • Akt2tm1e(KOMP)Wtsi
    TRACHEA, HET, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    LUNG, HET, Female, WTSI
sensory organ (2)
  • Akt2tm1e(KOMP)Wtsi
    AURICLE, SKIN, HET, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    EYE, HET, Female, WTSI
set of connective tissues (2)
  • Akt2tm1e(KOMP)Wtsi
    BROWN ADIPOSE TISSUE, HET, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    WHITE ADIPOSE TISSUE, HET, Female, WTSI
cardiovascular system (1)
  • Akt2tm1e(KOMP)Wtsi
    BLOOD VESSEL, HET, Female, WTSI
integumental system (1)
  • Akt2tm1e(KOMP)Wtsi
    AURICLE, SKIN, HET, Female, WTSI
urinary system (1)
  • Akt2tm1e(KOMP)Wtsi
    LOWER URINARY TRACT, HET, Male, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (167)
  • Akt2tm1e(KOMP)Wtsi
    HOM, Male, WTSI
  • Akt2tm1e(KOMP)Wtsi
    HOM, Male, WTSI
  • Akt2tm1e(KOMP)Wtsi
    HOM, Male, WTSI
  • Akt2tm1e(KOMP)Wtsi
    HOM, Male, WTSI
  • Akt2tm1e(KOMP)Wtsi
    HOM, Male, WTSI

show all 167 images

Tail Epidermis Wholemount (5)
  • Akt2tm1e(KOMP)Wtsi
    TAIL SKIN, HET, Male, WTSI
  • Akt2tm1e(KOMP)Wtsi
    TAIL SKIN, HOM, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    TAIL SKIN, HOM, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    TAIL SKIN, HOM, Female, WTSI
  • Akt2tm1e(KOMP)Wtsi
    TAIL SKIN, HOM, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Akt2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Akt2tm40417(L1L2_gt0)
Vector
Gene