Gene: Inpp1

Order

Name inositol polyphosphate-1-phosphatase

Synonyms 2300002C06Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:104848    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Inpp1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Inpp1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased body weight Inpp1tm1a(KOMP)Wtsi HOM Female postnatal 1.91E-11
decreased body length Inpp1tm1a(KOMP)Wtsi HOM Female Male postnatal 2.52E-6
increased body weight Inpp1tm1a(KOMP)Wtsi HOM Male postnatal 9.72E-6
abnormal behavior Inpp1tm1a(KOMP)Wtsi HOM Female postnatal 7.17E-5
increased circulating chloride level Inpp1tm1a(KOMP)Wtsi HOM Female Male postnatal 9.12E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/2)
Aorta 2 No
Blood vessel 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system postnatal mouse respiratory system nervous system set of connective tissues reproductive system immune system integumental system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (11)
  • Inpp1tm1a(KOMP)Wtsi
    skin, pinna, HET, Female, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    brain, HET, Male, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    spinal cord, HET, Female, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    cartilage tissue, HET, Female, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    testis, HET, Male, WTSI

show all 11 images

trunk (7)
  • Inpp1tm1a(KOMP)Wtsi
    spinal cord, HET, Female, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    uterus, oviduct, HET, Female, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    trachea, HET, Male, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    kidney, HET, Male, WTSI

show all 7 images

nervous system (3)
  • Inpp1tm1a(KOMP)Wtsi
    brain, HET, Male, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    spinal cord, HET, Female, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    peripheral nervous system, HET, Female, WTSI
reproductive system (2)
  • Inpp1tm1a(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    uterus, oviduct, HET, Female, WTSI
endocrine system (1)
  • Inpp1tm1a(KOMP)Wtsi
    adrenal gland, HET, Male, WTSI
immune system (1)
  • Inpp1tm1a(KOMP)Wtsi
    thymus, HET, Female, WTSI
integumental system (1)
  • Inpp1tm1a(KOMP)Wtsi
    skin, pinna, HET, Female, WTSI
respiratory system (1)
  • Inpp1tm1a(KOMP)Wtsi
    trachea, HET, Male, WTSI
sensory organ (1)
  • Inpp1tm1a(KOMP)Wtsi
    skin, pinna, HET, Female, WTSI
set of connective tissues (1)
  • Inpp1tm1a(KOMP)Wtsi
    cartilage tissue, HET, Female, WTSI
urinary system (1)
  • Inpp1tm1a(KOMP)Wtsi
    kidney, HET, Male, WTSI

Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    45 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    15 Images
  • Eye Morphology: Images Slit Lamp
    6 Images
  • X-ray: XRay Images Skull Lateral Orientation
    16 Images
  • X-ray: XRay Images Lateral Orientation
    32 Images
  • X-ray: XRay Images Forepaw
    14 Images
  • Eye Morphology: Images Ophthalmoscopy
    1 Images
Legacy Phenotype Associated Images
Xray (217)
  • Inpp1tm1a(KOMP)Wtsi
    body, HOM, Female, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    head, HOM, Female, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    head, HOM, Female, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    body, HOM, Female, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    head, HOM, Female, WTSI

show all 217 images

Eye Morphology (8)
  • Inpp1tm1a(KOMP)Wtsi
    eye, synechia, HOM, Male, WTSI
  • Inpp1tm1b(KOMP)Wtsi
    right eye, HOM, Female, WTSI
  • Inpp1tm1b(KOMP)Wtsi
    left eye, HOM, Female, WTSI
  • Inpp1tm1b(KOMP)Wtsi
    cornea/lens fusion, HOM, Female, WTSI
  • Inpp1tm1b(KOMP)Wtsi
    left eye, HOM, Female, WTSI

show all 8 images

Skin Histopathology (4)
  • Inpp1tm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI
  • Inpp1tm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI
  • Inpp1tm1b(KOMP)Wtsi
    back skin, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Inpp1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Inpp1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Inpp1tm44992(L1L2_gt0)
Vector
Gene
Inpp1tm44992(L1L2_gt0_Del_LacZ)
Vector
Gene