Gene: Lcp1

Order

Name lymphocyte cytosolic protein 1

Synonyms
  • L-fimbrin
  • D14Ertd310e
  • Pls2
  • L-plastin

Status ES CellsMice
tm1e
Mice
tm1e.1
phenotype data available

Links MGI:104808    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Lcp1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Lcp1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Lcp1tm1e.1(KOMP)Wtsi HOM Female Male n/a 0.0
abnormal sleep behavior Lcp1tm1e.1(KOMP)Wtsi HET Male postnatal 2.77E-6
increased fasted circulating glucose level Lcp1tm1e.1(KOMP)Wtsi HET Male postnatal 3.45E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Epididymis 2 No (18/134)
Esophagus 2 No (7/415)
Eye 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584)
Large intestine 2 No (10/584) (1/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (1/2)
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Submandibular gland 2 No (2/132)
Testis 2 No (2/584)
Thalamus 2 No
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Urinary bladder 2 No
Uterus 2 No
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    digestive system
    nervous system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (2/2)
Dorsal root ganglion 2 (1/47)
Ear 2 (1/485) (1/2)
Embryo 2 (1/485) (2/2)
Eye 2 (1/485) (1/2)
Foot 2 (1/485) (1/2)
Forebrain 2 (1/485) (2/2)
Forelimb 2 (1/485) (1/2)
Fronto-nasal process 2 (1/48) Image Only
Hand 2 (1/485) (1/2)
Head 2 (5/485) (2/2)
Heart 2 (1/485) (1/2)
Hindbrain 2 (6/485) (2/2)
Hindlimb 2 (1/485) (1/2)
Liver 2 (1/485)
Lung 2 (1/485) Image Only
Mandibular process 2 (1/485) (1/2)
Maxillary process 2 (1/485) (1/2)
Midbrain 2 (1/485) (1/2)
Nose 2 (1/51) (2/2)
Oral cavity 2 (1/485) Image Only
Skin 2 (1/485) (1/2)
Spinal cord 2 (1/50) (1/2)
Tail 2 (1/485) (1/2)
Tail somite 2 (1/485) (1/2)


Associated Images

Associated Images
  • Electroretinography 2: Rod and cone PDF
    4 Images
  • Sleep Wake: Wake state (bmp file)
    10 Images
  • Embryo LacZ: LacZ images wholemount
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Lcp1tm1e(KOMP)Wtsi Targeted, non-conditional allele
Vector
Gene
Lcp1tm1e.1(KOMP)Wtsi
Vector
Gene
Lcp1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Lcp1tm43058(L1L2_Bact_P)
Vector
Gene
Lcp1tm43058(L1L2_gt1)
Vector
Gene