Gene: Pdcd2

Order

Name programmed cell death 2

Synonyms RP-8

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:104643    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Pdcd2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Pdcd2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
embryonic lethality prior to organogenesis Pdcd2tm1b(EUCOMM)Wtsi HOM Female Male embryonic day 9.5 0.0
prenatal lethality prior to heart atrial septation Pdcd2tm1b(EUCOMM)Wtsi HOM Female Male embryonic day 14.5 0.0
preweaning lethality, complete penetrance Pdcd2tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
abnormal eyelid morphology Pdcd2tm1b(EUCOMM)Wtsi HET Male postnatal 3.83E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
reproductive system (1)
  • Pdcd2tm1b(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
trunk (1)
  • Pdcd2tm1b(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI

Associated Images

Associated Images
  • DSS Histology
    6 Images
  • Anti-nuclear antibody assay
    6 Images
  • X-ray: XRay Images Dorso Ventral
    43 Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    15 Images
  • X-ray: XRay Images Forepaw
    14 Images
  • Eye Morphology: Images Slit Lamp
    4 Images
Legacy Phenotype Associated Images
Xray (71)
  • Pdcd2tm1b(EUCOMM)Wtsi
    HET, Female, WTSI
  • Pdcd2tm1b(EUCOMM)Wtsi
    HET, Female, WTSI
  • Pdcd2tm1b(EUCOMM)Wtsi
    HET, Female, WTSI
  • Pdcd2tm1b(EUCOMM)Wtsi
    HET, Female, WTSI
  • Pdcd2tm1b(EUCOMM)Wtsi
    HET, Female, WTSI

show all 71 images

Eye Morphology (4)
  • Pdcd2tm1b(EUCOMM)Wtsi
    hair loss, HET, Male, WTSI
  • Pdcd2tm1b(EUCOMM)Wtsi
    hair loss, HET, Male, WTSI
  • Pdcd2tm1b(EUCOMM)Wtsi
    hair loss, HET, Male, WTSI
  • Pdcd2tm1b(EUCOMM)Wtsi
    hair loss, HET, Male, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Pdcd2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Pdcd2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Pdcd2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene