Gene: Aqp1

Name aquaporin 1

Synonyms CHIP28

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:103201   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Aqp1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Aqp1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased circulating alkaline phosphatase level Aqp1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.61E-30
hypoactivity Aqp1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.73E-14
abnormal behavior Aqp1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.0E-12
increased circulating total protein level Aqp1tm1b(EUCOMM)Wtsi HOM Female postnatal 1.09E-6
decreased grip strength Aqp1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.15E-6
impaired glucose tolerance Aqp1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 2.73E-6
increased circulating HDL cholesterol level Aqp1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 5.81E-6
increased circulating cholesterol level Aqp1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 4.8E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/354) (2/2)
Aorta 2 No (2/530) (2/2)
Bone 2 No (1/515) (2/2)
Brain 2 No (8/530) (2/2)
Brainstem 2 No (5/530)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/530) (2/2)
Cerebellum 2 No (6/530)
Cerebral cortex 2 No (6/530)
Esophagus 2 No (1/354) (2/2)
Eye 2 No (1/530) (2/2)
Gall bladder 2 No (2/2)
Heart 2 No (4/530) (1/2)
Hippocampus 2 No (7/530)
Hypothalamus 2 No (5/529)
Kidney 2 No (13/530) (2/2)
Large intestine 2 No (7/530) (2/2)
Liver 2 No (1/2)
Lower urinary tract 2 No (3/530) (2/2)
Lung 2 No (4/530) (2/2)
Lymph node 2 No (2/530) (2/2)
Mammary gland 2 No (1/2)
Olfactory lobe 2 No (3/354)
Oral epithelium 2 No (2/2)
Ovary 2 No (1/530)
Oviduct 2 No (1/530) (1/2)
Pancreas 2 No (2/530)
Parathyroid gland 2 No (2/516)
Peripheral nervous system 2 No (4/530) (2/2)
Peyer's patch 2 No (1/354) (2/2)
Pituitary gland 2 No (2/530) (2/2)
Prostate gland 2 No (3/530)
Skeletal muscle 2 No (2/2)
Skin 2 No (2/530) (2/2)
Small intestine 2 No (5/530) (2/2)
Spinal cord 2 No (5/530)
Spleen 2 No (3/530)
Stomach 2 No (5/530) (2/2)
Striatum 2 No (6/530)
Testis 2 No (7/530) (1/2)
Thymus 2 No (1/530) (2/2)
Thyroid gland 2 No (11/530)
Trachea 2 No (5/530) (2/2)
Uterus 2 No (1/530) (1/2)
Vascular system 2 No (1/354) (2/2)
White adipose tissue 2 No (1/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system set of connective tissues reproductive system musculoskeletal system adipose tissue
    trunk
    postnatal mouse
    nervous system sensory organ
    immune system
    exocrine system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    4 Images
  • X-ray: XRay Images Lateral Orientation
    12 Images
  • X-ray: XRay Images Dorso Ventral
    12 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    12 Images
  • Echo: M-Mode Images
    32 Images
  • Adult LacZ: LacZ Images Wholemount
    24 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Aqp1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Aqp1tm44540(L1L2_st0) KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Aqp1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene