All nervous system phenotype, behavior/neurological phenotype data for Ewsr1

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status Graph
Ewsr1tm1b(EUCOMM)Wtsi TCP Open Field / Periphery resting time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.16051 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Open Field / Center permanence time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.026921 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Open Field / Whole arena resting time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00064479 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Combined SHIRPA and Dysmorphology / Activity (body position) HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Ewsr1tm1b(EUCOMM)Wtsi TCP Combined SHIRPA and Dysmorphology / Head bobbing HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Ewsr1tm1b(EUCOMM)Wtsi TCP Combined SHIRPA and Dysmorphology / Trunk curl HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Ewsr1tm1b(EUCOMM)Wtsi TCP Open Field / Center resting time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00015846 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Combined SHIRPA and Dysmorphology / Locomotor activity HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.58534 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Eye Morphology / Optic Disc HET 6f:8m Fisher Exact Test framework 1.0000 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Open Field / Center average speed HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00046734 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Gross Morphology Embryo E12.5 / Midbrain morphology HOM f:m Supplied as data Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Gross Morphology Embryo E12.5 / Midbrain morphology HOM f:m Supplied as data Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Gross Morphology Embryo E12.5 / Midbrain morphology HET f:m Supplied as data Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Gross Morphology Embryo E12.5 / Midbrain morphology HET f:m Supplied as data Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Combined SHIRPA and Dysmorphology / Contact righting HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Ewsr1tm1b(EUCOMM)Wtsi TCP Open Field / Distance travelled - total HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0030917 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Open Field / Number of rears - total HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.85409 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Combined SHIRPA and Dysmorphology / Unexpected behaviors HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Ewsr1tm1b(EUCOMM)Wtsi TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.10544 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Open Field / Periphery permanence time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.026912 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Combined SHIRPA and Dysmorphology / Gait HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Ewsr1tm1b(EUCOMM)Wtsi TCP Gross Morphology Embryo E12.5 / Neural Tube Closure HOM f:m Supplied as data Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Gross Morphology Embryo E12.5 / Neural Tube Closure HOM f:m Supplied as data Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Gross Morphology Embryo E12.5 / Neural Tube Closure HET f:m Supplied as data Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Gross Morphology Embryo E12.5 / Neural Tube Closure HET f:m Supplied as data Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0032684 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Gross Morphology Embryo E12.5 / Forebrain morphology HET f:m Supplied as data Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Gross Morphology Embryo E12.5 / Forebrain morphology HOM f:m Supplied as data Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Gross Morphology Embryo E12.5 / Forebrain morphology HET f:m Supplied as data Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Gross Morphology Embryo E12.5 / Forebrain morphology HOM f:m Supplied as data Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.94097 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Indirect Calorimetry / Total food intake HET 7f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00020923 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Open Field / Latency to center entry HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.12554 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Open Field / Percentage center time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.026923 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Combined SHIRPA and Dysmorphology / Aggression HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Ewsr1tm1b(EUCOMM)Wtsi TCP Open Field / Number of center entries HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.28676 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Combined SHIRPA and Dysmorphology / Tremor HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Ewsr1tm1b(EUCOMM)Wtsi TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.24605 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0021253 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Grip Strength / Forelimb grip strength measurement mean HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.98998 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Combined SHIRPA and Dysmorphology / Startle response HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Ewsr1tm1b(EUCOMM)Wtsi TCP Open Field / Periphery average speed HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.047371 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.45348 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Combined SHIRPA and Dysmorphology / Limb grasp HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Ewsr1tm1b(EUCOMM)Wtsi TCP Eye Morphology / Pupil Light Response HET 6f:8m Fisher Exact Test framework 1.0000 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Open Field / Whole arena average speed HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.14661 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Gross Morphology Embryo E12.5 / Hindbrain morphology HET f:m Supplied as data Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Gross Morphology Embryo E12.5 / Hindbrain morphology HET f:m Supplied as data Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Gross Morphology Embryo E12.5 / Hindbrain morphology HOM f:m Supplied as data Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Gross Morphology Embryo E12.5 / Hindbrain morphology HOM f:m Supplied as data Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Open Field / Center distance travelled HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.97713 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Combined SHIRPA and Dysmorphology / Vocalization HET 8f:8m Fisher Exact Test framework 1.0000 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Open Field / Periphery distance travelled HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 6.0600E-06 Success
Ewsr1tm1b(EUCOMM)Wtsi TCP Grip Strength / Forelimb and hindlimb grip strength measurement mean HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.42664 Success

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