All behavior/neurological phenotype, nervous system phenotype data for Pkn3

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status Graph
Pkn3tm1.1(KOMP)Vlcg JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 6f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.50046 Success
Pkn3tm1.1(KOMP)Vlcg JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 2f:2m Not processed 1.0000 FAILED - Not enough mutant or control data
Pkn3tm1.1(KOMP)Vlcg JAX Sleep Wake / Light sleep bout lengths standard deviation HOM 6f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.39815 Success
Pkn3tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:8m Fisher Exact Test framework 1.0000 Success
Pkn3tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Pkn3tm1.1(KOMP)Vlcg JAX Light-Dark Test / Percent time in light HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.78167 Success
Pkn3tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:8m Fisher Exact Test framework 1.0000 Success
Pkn3tm1.1(KOMP)Vlcg JAX Light-Dark Test / Side changes HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.45683 Success
Pkn3tm1.1(KOMP)Vlcg JAX Hole-board Exploration / Total holepokes HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.84787 Success
Pkn3tm1.1(KOMP)Vlcg JAX Open Field / Distance travelled - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.41127 Success
Pkn3tm1.1(KOMP)Vlcg JAX Sleep Wake / Dark sleep bout lengths mean HOM 6f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.60918 Success
Pkn3tm1.1(KOMP)Vlcg JAX Open Field / Number of rears - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.13179 Success
Pkn3tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:8m Fisher Exact Test framework 1.0000 Success
Pkn3tm1.1(KOMP)Vlcg JAX Light-Dark Test / Light side time spent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.79834 Success
Pkn3tm1.1(KOMP)Vlcg JAX Open Field / Periphery permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.15596 Success
Pkn3tm1.1(KOMP)Vlcg JAX Open Field / Percentage center time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.15637 Success
Pkn3tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Aggression HOM 8f:8m Fisher Exact Test framework 1.0000 Success
Pkn3tm1.1(KOMP)Vlcg JAX Light-Dark Test / Time mobile light side HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.83622 Success
Pkn3tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.61919 Success
Pkn3tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Startle response HOM 8f:8m Fisher Exact Test framework 1.0000 Success
Pkn3tm1.1(KOMP)Vlcg JAX Sleep Wake / Breath rate during sleep standard deviation HOM 6f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.45809 Success
Pkn3tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:8m Fisher Exact Test framework 1.0000 Success
Pkn3tm1.1(KOMP)Vlcg JAX Open Field / Periphery distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.18489 Success
Pkn3tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep daily percent HOM 6f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.77222 Success
Pkn3tm1.1(KOMP)Vlcg JAX Light-Dark Test / Dark side time spent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.79834 Success
Pkn3tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.95452 Success
Pkn3tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep light phase percent HOM 6f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.39330 Success
Pkn3tm1.1(KOMP)Vlcg JAX Open Field / Center permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.15637 Success
Pkn3tm1.1(KOMP)Vlcg JAX Open Field / Whole arena resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.68386 Success
Pkn3tm1.1(KOMP)Vlcg JAX Sleep Wake / Peak wake with respect to dark onset median HOM 6f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.49109 Success
Pkn3tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.034930 Success
Pkn3tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.094482 Success
Pkn3tm1.1(KOMP)Vlcg JAX Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.0000 Success
Pkn3tm1.1(KOMP)Vlcg JAX Light-Dark Test / Time mobile dark side HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.036162 Success
Pkn3tm1.1(KOMP)Vlcg JAX Light-Dark Test / Fecal boli HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.47472 Success
Pkn3tm1.1(KOMP)Vlcg JAX Open Field / Center average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.72971 Success
Pkn3tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:8m Fisher Exact Test framework 1.0000 Success
Pkn3tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep dark phase percent HOM 6f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.67776 Success
Pkn3tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0022267 Success
Pkn3tm1.1(KOMP)Vlcg JAX Sleep Wake / Breath rate during sleep mean HOM 6f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.062000 Success
Pkn3tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Gait HOM 8f:8m Fisher Exact Test framework 1.0000 Success
Pkn3tm1.1(KOMP)Vlcg JAX Rotarod / Learning slope HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.19819 Success
Pkn3tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.95910 Success
Pkn3tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.84141 Success
Pkn3tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep bout lengths mean HOM 6f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.86518 Success
Pkn3tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tremor HOM 8f:8m Fisher Exact Test framework 1.0000 Success
Pkn3tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.46984 Success
Pkn3tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.20781 Success
Pkn3tm1.1(KOMP)Vlcg JAX Light-Dark Test / Latency to first transition into dark HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.89455 Success
Pkn3tm1.1(KOMP)Vlcg JAX Rotarod / Learning difference HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.066797 Success
Pkn3tm1.1(KOMP)Vlcg JAX Open Field / Periphery average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.35854 Success
Pkn3tm1.1(KOMP)Vlcg JAX Sleep Wake / Dark sleep bout lengths standard deviation HOM 6f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.97391 Success
Pkn3tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:8m Fisher Exact Test framework 1.0000 Success
Pkn3tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Light Response HOM 8f:8m Fisher Exact Test framework 1.0000 Success
Pkn3tm1.1(KOMP)Vlcg JAX Open Field / Whole arena average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.41236 Success
Pkn3tm1.1(KOMP)Vlcg JAX Sleep Wake / Light sleep bout lengths mean HOM 6f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.96134 Success
Pkn3tm1.1(KOMP)Vlcg JAX Open Field / Center distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.25369 Success
Pkn3tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep bout lengths standard deviation HOM 6f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.49093 Success
Pkn3tm1.1(KOMP)Vlcg JAX Light-Dark Test / Percent time in dark HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.78167 Success
Pkn3tm1.1(KOMP)Vlcg JAX Rotarod / Average duration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.094917 Success

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