Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
8.76×10-06
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.929
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HOM
|
246f:399m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HET
|
236f:m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
7f:9m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HET
|
5f:m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
7f:9m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Percent time in light
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0429
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Percent time in light
|
HET
|
5f:m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.464
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Center average speed
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0298
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Center average speed
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.919
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Center permanence time
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
9.29×10-12
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Center permanence time
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.183
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Side changes
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.129
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Side changes
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.626
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Hole-board Exploration / Total holepokes
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.258
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Hole-board Exploration / Total holepokes
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.303
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HET
|
5f:m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
7f:9m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Light side time spent
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.314
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Light side time spent
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.691
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.311
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.822
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
4.58×10-05
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.933
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Number of Rears
|
HET
|
20f:m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Number of Rears
|
HOM
|
28f:36m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Time mobile light side
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000948
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Time mobile light side
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.667
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
0.000902
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.0334
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Percentage center time
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
9.29×10-12
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Percentage center time
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.183
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HET
|
5f:m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
7f:9m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Distance travelled
|
HET
|
20f:m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Distance travelled
|
HOM
|
28f:36m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
0.619
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
7f:9m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HET
|
5f:m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Dark side time spent
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.314
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Dark side time spent
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.691
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.00707
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Number of rears - total
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.116
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Number of rears - total
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.273
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
21f:27m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.394
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.459
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Eye Morphology / Optic Disc
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Eye Morphology / Optic Disc
|
HET
|
5f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
7f:9m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HET
|
5f:m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
7f:9m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Periphery average speed
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
1.61×10-05
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Periphery average speed
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.742
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.482
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.764
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Fecal boli
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.798
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Fecal boli
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.823
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0218
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
21f:27m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
8.57×10-06
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.930
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
7f:9m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HET
|
5f:m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
9.35×10-12
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.183
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.559
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
7f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.611
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.232
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.234
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0994
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.826
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.00222
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.355
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.317
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HET
|
5f:m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.829
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HET
|
5f:m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
7f:9m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Eye Morphology / Pupil Light Response
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
4.88×10-10
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Eye Morphology / Pupil Light Response
|
HET
|
5f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
0.390
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
7f:9m
|
|
|
NotProcessed |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Percent time in dark
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0429
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Light-Dark Test / Percent time in dark
|
HET
|
5f:m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.464
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Center distance travelled
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00
|
Successful |
Zbtb43tm1b(KOMP)Mbp
|
JAX
|
Open Field - centre start / Center distance travelled
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.180
|
Successful |