All nervous system phenotype, behavior/neurological phenotype data for Eps8l1

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status Graph
Eps8l1tm2b(KOMP)Wtsi UC Davis Open Field / Center permanence time HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.72624 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Open Field / Whole arena resting time HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.65406 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Activity (body position) HOM 10f:8m Fisher Exact Test framework 1.0000 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Head bobbing HOM 10f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Eps8l1tm2b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Trunk curl HOM 10f:8m Fisher Exact Test framework 1.0000 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Locomotor activity HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.72379 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Eye Morphology / Optic Disc HOM 10f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Eps8l1tm2b(KOMP)Wtsi UC Davis Open Field / Center average speed HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.91771 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Contact righting HOM 10f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Eps8l1tm2b(KOMP)Wtsi UC Davis Open Field / Distance travelled - total HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.66800 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Open Field / Number of rears - total HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.011427 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 10f:8m Fisher Exact Test framework 0.26238 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Open Field / Periphery permanence time HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.72604 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Gait HOM 10f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Eps8l1tm2b(KOMP)Wtsi UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.19579 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.23849 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Open Field / Percentage center time HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.72624 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Aggression HOM 10f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Eps8l1tm2b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tremor HOM 10f:8m Fisher Exact Test framework 1.0000 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.041256 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.12003 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Grip Strength / Forelimb grip strength measurement mean HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.37241 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Startle response HOM 10f:8m Fisher Exact Test framework 1.0000 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Open Field / Periphery average speed HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.66966 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Limb grasp HOM 10f:8m Fisher Exact Test framework 0.053867 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Open Field / Whole arena average speed HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.66800 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Open Field / Center distance travelled HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.84642 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Vocalization HOM 10f:8m Fisher Exact Test framework 0.053094 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Open Field / Periphery distance travelled HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.64627 Success
Eps8l1tm2b(KOMP)Wtsi UC Davis Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 10f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.88569 Success

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