All nervous system phenotype, behavior/neurological phenotype data for Ypel1

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status Graph
Ypel1tm1.1(KOMP)Vlcg JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 6f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.11140 Success
Ypel1tm1.1(KOMP)Vlcg JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 1f:1m Not processed 1.0000 FAILED - Not enough mutant or control data
Ypel1tm1.1(KOMP)Vlcg JAX Sleep Wake / Light sleep bout lengths standard deviation HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.74064 Success
Ypel1tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Activity (body position) HOM 7f:6m Fisher Exact Test framework 1.0000 Success
Ypel1tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head bobbing HOM 7f:6m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Ypel1tm1.1(KOMP)Vlcg JAX Light-Dark Test / Percent time in light HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.19895 Success
Ypel1tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Trunk curl HOM 7f:6m Fisher Exact Test framework 1.0000 Success
Ypel1tm1.1(KOMP)Vlcg JAX Light-Dark Test / Side changes HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.27378 Success
Ypel1tm1.1(KOMP)Vlcg JAX Hole-board Exploration / Total holepokes HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0011437 Success
Ypel1tm1.1(KOMP)Vlcg JAX Open Field / Distance travelled - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.18036 Success
Ypel1tm1.1(KOMP)Vlcg JAX Sleep Wake / Dark sleep bout lengths mean HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.66790 Success
Ypel1tm1.1(KOMP)Vlcg JAX Open Field / Number of rears - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.28403 Success
Ypel1tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 7f:6m Fisher Exact Test framework 1.0000 Success
Ypel1tm1.1(KOMP)Vlcg JAX Light-Dark Test / Light side time spent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.094144 Success
Ypel1tm1.1(KOMP)Vlcg JAX Open Field / Periphery permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.11367 Success
Ypel1tm1.1(KOMP)Vlcg JAX Open Field / Percentage center time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.11372 Success
Ypel1tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Aggression HOM 7f:6m Fisher Exact Test framework 1.0000 Success
Ypel1tm1.1(KOMP)Vlcg JAX Light-Dark Test / Time mobile light side HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.080588 Success
Ypel1tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb grip strength measurement mean HOM 5f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.70127 Success
Ypel1tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Startle response HOM 7f:6m Fisher Exact Test framework 1.0000 Success
Ypel1tm1.1(KOMP)Vlcg JAX Sleep Wake / Breath rate during sleep standard deviation HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.37474 Success
Ypel1tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vocalization HOM 7f:6m Fisher Exact Test framework 1.0000 Success
Ypel1tm1.1(KOMP)Vlcg JAX Open Field / Periphery distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.38789 Success
Ypel1tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep daily percent HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.90329 Success
Ypel1tm1.1(KOMP)Vlcg JAX Light-Dark Test / Dark side time spent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.094144 Success
Ypel1tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 5f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.69224 Success
Ypel1tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep light phase percent HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.11230 Success
Ypel1tm1.1(KOMP)Vlcg JAX Open Field / Center permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.11372 Success
Ypel1tm1.1(KOMP)Vlcg JAX Open Field / Whole arena resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.074462 Success
Ypel1tm1.1(KOMP)Vlcg JAX Sleep Wake / Peak wake with respect to dark onset median HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.44171 Success
Ypel1tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb grip strength normalised against body weight HOM 5f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.63755 Success
Ypel1tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Locomotor activity HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.61590 Success
Ypel1tm1.1(KOMP)Vlcg JAX Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.0000 Success
Ypel1tm1.1(KOMP)Vlcg JAX Light-Dark Test / Time mobile dark side HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.80925 Success
Ypel1tm1.1(KOMP)Vlcg JAX Light-Dark Test / Fecal boli HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.49797 Success
Ypel1tm1.1(KOMP)Vlcg JAX Open Field / Center average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.57242 Success
Ypel1tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Contact righting HOM 7f:6m Fisher Exact Test framework 1.0000 Success
Ypel1tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep dark phase percent HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.30060 Success
Ypel1tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 5f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.79072 Success
Ypel1tm1.1(KOMP)Vlcg JAX Sleep Wake / Breath rate during sleep mean HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.018435 Success
Ypel1tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Gait HOM 7f:6m Fisher Exact Test framework 1.0000 Success
Ypel1tm1.1(KOMP)Vlcg JAX Rotarod / Learning slope HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.49610 Success
Ypel1tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.66872 Success
Ypel1tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ACS_033_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Ypel1tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.013081 Success
Ypel1tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ACS_035_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Ypel1tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep bout lengths mean HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.28157 Success
Ypel1tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tremor HOM 7f:6m Fisher Exact Test framework 1.0000 Success
Ypel1tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.10271 Success
Ypel1tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ACS_034_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Ypel1tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.10236 Success
Ypel1tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ACS_006_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Ypel1tm1.1(KOMP)Vlcg JAX Light-Dark Test / Latency to first transition into dark HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.26732 Success
Ypel1tm1.1(KOMP)Vlcg JAX Rotarod / Learning difference HOM 8f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.33274 Success
Ypel1tm1.1(KOMP)Vlcg JAX Open Field / Periphery average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.20999 Success
Ypel1tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Limb grasp HOM 7f:6m Fisher Exact Test framework 0.37133 Success
Ypel1tm1.1(KOMP)Vlcg JAX Sleep Wake / Dark sleep bout lengths standard deviation HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.74840 Success
Ypel1tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Light Response HOM 8f:8m Fisher Exact Test framework 1.0000 Success
Ypel1tm1.1(KOMP)Vlcg JAX Open Field / Whole arena average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.18424 Success
Ypel1tm1.1(KOMP)Vlcg JAX Sleep Wake / Light sleep bout lengths mean HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.36314 Success
Ypel1tm1.1(KOMP)Vlcg JAX Open Field / Center distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.11940 Success
Ypel1tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep bout lengths standard deviation HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.97341 Success
Ypel1tm1.1(KOMP)Vlcg JAX Light-Dark Test / Percent time in dark HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.20254 Success

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