Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail - thickness
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Embryo Size
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw footpad size
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - back
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Limb Bud Morphology
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / External genitalia morphology
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Snout morphology
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
0.222
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Cytotoxic T cell function / Incubation time
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Mean cell hemoglobin concentration
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0119
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hematology / Mean cell hemoglobin concentration
|
HET
|
3f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.600
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hematology / Mean cell hemoglobin concentration
|
HET
|
3f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.809
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Kyphosis
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Kyphosis
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Comment
|
HET
|
f:m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / CD5+ gd T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Body weight before experiment
|
HET
|
f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Lumbar processes
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Lumbar processes
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Incisors morphology
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total myeloid cells - % of CD45+
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 average volume of LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Auditory Brain Stem Response / 6kHz-evoked ABR Threshold
|
HET
|
4f:4m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0495
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / 6kHz-evoked ABR Threshold
|
HET
|
f:4m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector gd T cells - % of gd T cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 LC count
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Peyers Patch
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Thyroid
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Thyroid
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Thyroid
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Plasmacytoid DC - % of DC
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting Treg cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector Treg cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Lens Opacity
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Lens Opacity
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb skin appearance
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin texture - back paws
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / LDL-cholesterol
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.715
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Microphthalmia
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Conventional DC (cDC) - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Pro-B cells (Hardy fraction C) - cell count
|
HET
|
3f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Follicular B cells - % of B2 cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindlimb size
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Dark side time spent
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0103
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Marginal zone precursor B cells - % of CD45+
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Eosinophils - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Zygomatic bone
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Zygomatic bone
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / T cells - cell count
|
HET
|
3f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Calcium
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0551
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Calcium
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.808
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / 3i B cell panel
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / B cell panel singlets cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Shape of ribs
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Shape of ribs
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / B cell panel singlets cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electrocardiogram (ECG) / Number of signals
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin color - ear
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total CD4- NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / CD4+ T helper cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Rotarod / Learning slope
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00881
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total ab T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Pro-B cells (Hardy fractions B and C) - % of CD45
|
HET
|
3f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Myeloid cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Auditory Brain Stem Response / 30kHz-evoked ABR Threshold
|
HET
|
4f:4m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.000449
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / 30kHz-evoked ABR Threshold
|
HET
|
f:4m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / B2 t1 + t2 cells - % of B2 cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total CD8+ T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Germinal centre B cells - % of B2 cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Viability Primary Screen / Viability Outcome
|
HOM
|
f:m
|
Supplied as data
|
0.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Viability Primary Screen / Viability Outcome
|
HOM
|
f:m
|
Supplied as data
|
0.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Genitalia - morphology
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD4- NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Placenta E9.5 / Placenta Development
|
HET
|
12f:10m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / B cell panel lymphocyte gate cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Lymph node
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Lymph node
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Lymph node
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total gd T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head bobbing/circling
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total CD5+ T cells - IMPC panel cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Corneal vascularization
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Corneal vascularization
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Retinal Blood Vessels Pattern
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retinal Blood Vessels Pattern
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 count of vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Triglycerides
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0398
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Triglycerides
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0476
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / B2 t1 + t2 cells - % of CD45+
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head size
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Platelet count
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.312
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hematology / Platelet count
|
HET
|
3f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.422
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hematology / Platelet count
|
HET
|
3f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.844
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / External genitalia
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Cytotoxic T cell function / Days post activation
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindlimb morphology
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector Treg cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Follicular B cells - % of B2 cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Ly6C+ CD5+ T cells - % of CD5+ T cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
0.209
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 ratio of CD45+ vg5- MHC II- cells/vg5+ DETC
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Thymus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Thymus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Thymus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total DC - % of myeloid cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimbs - position
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Neural Tube Closure
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb skin colour
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Peripheral Nervous System
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Scoliosis
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Scoliosis
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Vesicular Gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Incisor colour
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Plasmacytoid DC - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Time mobile light side
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0135
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Cytotoxic T cell function / Comment
|
HET
|
f:m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Macrophages - % of myeloid cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Conventional DC (cDC) - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail - morphology
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Blebs
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / B1a cells - % of B cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector CD4- NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / CD5+ gd T cells - % of gd T cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 ratio of vg5+ DETC/LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HET
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0377
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.219
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting CD4+ NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting Treg cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Myeloid panel lymphocyte gate cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Adrenal gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Lens
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
0.262
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Lens
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector CD4+ T helper cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / CD11b-high cDC - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total DC - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average roundness of vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Granulocytes - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / 3i Myeloid panel
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.863
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Contact righting reflex
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin color - snout
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ CD8+ T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Skin
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Skin
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Skin
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 ratio of CD45+ vg5- MHC II- cells/vg5+ DETC
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Comments
|
HET
|
f:m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / HDL-cholesterol
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0457
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / HDL-cholesterol
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.465
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Persistence of hyaloid vascular system
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
0.731
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Persistence of hyaloid vascular system
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / B2 t3 + f1+ f2 + gc cells - % of CD45+
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Eosinophils - % of myeloid cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 CD45+ vg5- MHC II- cell count
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / B2 t3 + f1 + f2 + gc cells - % of B2 cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Processes on vertebrae
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Granulocytes - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Maxilla/Pre-maxilla
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Maxilla/Pre-maxilla
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total CD4+ T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average volume of CD45+ vg5- MHC II- cells
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Mature NK cells - % of NK cellls
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / T cell panel singlets cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Mouth morphology
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Transitional 2 B cells - % of B2 cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Gait (inc. ataxia)
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair appearance
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting NK cells - % of NK cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Caudal processes
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Caudal processes
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral skin appearance
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head morphology
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / B2 marginal zone + precursor cells - % of CD45+
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin texture - ear
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Body weight
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Body Composition (DEXA lean/fat) / Body weight
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / B2 marginal zone + precursor cells - % of B2 cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total DC - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Branchial arch morphology
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Transition
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alpha-amylase
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0758
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting Treg cells - % of Treg
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting CD4- NKT cells - % of CD4- NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Transitional 1 B cells - % of B2 cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Convulsions
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 CD45+ vg5- MHC II- cell count
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Embryo Size
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Genitalia - size
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Plasmacytoid DC - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 average branch length of LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Pallor
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw digit size
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total ab T cells - % of total T cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average branch length of LC
|
HET
|
2f:2m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Rod b-wave amplitude-right
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Placenta E9.5 / Placenta Vasculature
|
HET
|
12f:10m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Olfactory Lobe
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimbs - shape
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb grip strength measurement mean
|
HET
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
2.53×10-05
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0349
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Granulocytes + monocytes - % of myeloid cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Marginal zone B cells - % of CD45+
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Monocytes - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Pre-Day 10 Death
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Gall bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Gall bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Gall bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 average volume of vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Free fatty acids
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0720
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Free fatty acids
|
HET
|
6f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0899
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Cornea
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
0.301
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Cornea
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Germinal centre B cells - % of B2 cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting CD4+ T helper cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Auditory Brain Stem Response / 12kHz-evoked ABR Threshold
|
HET
|
4f:4m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0264
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / 12kHz-evoked ABR Threshold
|
HET
|
f:4m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.491
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Number of rears - total
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0495
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / CD4+ T helper cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Immature B cells (Hardy fraction E) - % of B220+
|
HET
|
3f:1m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting CD8+ T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector gd T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Memory B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Granulocytes + monocytes - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Periphery average speed
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.557
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Fecal boli
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.690
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ Treg cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Transitional 2 B cells - % of CD45+
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin texture - tail
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / IMPC panel lymphocyte gate cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Iris Pigmentation
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Iris Pigmentation
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Tissue dissociation method
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / CD11b-high cDC - % of cDC
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / BM panel singlets cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Cytotoxic T cell function / 0.3125:1 stdev
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector gd T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Thoracic processes
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Thoracic processes
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.386
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / CD103+ CD11b-low cDC - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Humerus
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Humerus
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.0279
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector CD4+ NKT cells - % of CD4+ NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average branch length of vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Large intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Large intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Large intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
0.388
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Viability E14.5-E15.5 Secondary Screen / Outcome
|
HOM
|
f:m
|
Supplied as data
|
0.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Monocytes - % of myeloid cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Total B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / B2 t1 + t2 cells - % of lymphocytes
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Anophthalmia
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Genitalia - presence
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Lordosis
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Lordosis
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral skin colour
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Eosinophils - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Memory B cells - % of B2 cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 CD45+ vg5- MHC II- cell count
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Sacral processes
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Sacral processes
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair length
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector Treg cells - % of Treg
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average branch length of LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw digit count
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / BM panel live cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total DC - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail - length
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Stomach
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Stomach
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Stomach
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Body weight after experiment
|
HET
|
f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Interpupillary distance
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / External genitalia size
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ NK cells - % of NK cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Memory B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Placenta E9.5 / Placenta Morphology
|
HET
|
12f:10m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimbs - size
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin texture - front paws
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Bone Area
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0625
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Body Composition (DEXA lean/fat) / Bone Area
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0842
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 tissue volume
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total CD4+ T cells - % of ab T cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Transitional 2 B cells - % of B2 cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average volume of vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Heart
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Heart
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Heart
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Granulocytes - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail skin colour
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Mature B cells (Hardy fraction F) - % of B220+
|
HET
|
3f:1m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair presence
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Transitional 1 B cells - % of B2 cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ Treg cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average volume of vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average branch length of vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin color - front paws
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Trachea
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Trachea
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Trachea
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total CD8+ T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Mature B cells (Hardy fraction F) - % of CD45+
|
HET
|
3f:1m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Glucose
|
HET
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.00148
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Glucose
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0163
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.616
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector CD8+ T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Pre-pro B cells (Hardy fraction A) - % of CD45+
|
HET
|
3f:1m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Skull shape
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Skull shape
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.591
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector CD4+ T helper cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Transitional 1 B cells - % of CD45+
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average volume of vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Spinal cord
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Oxygen consumption
|
HET
|
f:63m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forelimb
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Small intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Small intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Small intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Ly6C+ NKT cells - IMPC panel cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Visceral yolk sac morphology
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail - presence
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total CD8+ T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Pupil Light Response
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Pupil Light Response
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Corneal opacity
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
0.371
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Corneal opacity
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / CD11b-low cDC - % of cDC
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Cytotoxic T cell function / 0.625:1 stdev
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Prostate gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Shape of ribcage
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Shape of ribcage
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Macrophages - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / CD5+ gd T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Collagenase digestion
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Center distance travelled
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.855
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total CD4+ NKT cells - % of NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average branch length of vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / B cell panel CD45+ live cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alanine aminotransferase
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.586
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Alanine aminotransferase
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.790
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimb nail - shape
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Comment
|
HET
|
f:m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electrocardiogram (ECG) / RR
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.986
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Granulocytes - % of myeloid cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Eosinophils - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ NK cells - % of NK cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Naive CD8+ T cells - % of CD8+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Plasma cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Rod a-wave implicit time-right
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 ratio of contacting/not contacting vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of thoracic vertebrae
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Marginal zone precursor B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / CD11b-low cDC - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair colour
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / CD11b-low cDC - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Microcephaly
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair colour
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / NKT cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / NKT cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Granulocytes + monocytes - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Vibrissae - presence
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting gd T cells - % of gd T cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail skin appearance
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Percentage center time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.863
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Lower teeth appearance
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair presence
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
0.212
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / CD4+ T helper cells - % of CD4+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Left-right axis patterning
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total B2 cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Plasma cells - % of B2 cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total B2 cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Cytotoxic T cell function / Killing assay kit
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ gd T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Esophagus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Cytotoxic T cell function / 1.25:1 stdev
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting Treg cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Marginal zone B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna size
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ CD4- NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Esophagus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Esophagus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Esophagus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Memory B cells - % of B2 cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Vibrissae shape
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average volume of vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Creatine kinase
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.668
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total Treg cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / CD103+ CD11b-low cDC - % of CD11b-low cDC
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Body Composition (DEXA lean/fat) / Fat mass
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.225
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Fat mass
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
1.40×10-07
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Pro-B cells (Hardy fraction C) - % of B220+
|
HET
|
3f:1m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector CD8+ T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / B1a cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Thyroxine
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.280
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total myeloid cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Transitional 1 B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forelimb size
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Upper teeth appearance
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector NK cells - % of NK cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Pale yolk sac
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Eye
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw morphology
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total CD4- NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / B cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / B cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.296
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Marginal zone B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / Body weight
|
HET
|
f:4m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electrocardiogram (ECG) / PQ
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.858
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Liver
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Liver
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Liver
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Heart
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Ratio of contacting/not contacting vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Epididymis
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair colour pattern
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Myeloid panel CD45+ live cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Macrophages - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Late germinal centre B cells - % of GC cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Midbrain morphology
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting CD4- NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average no of branches on LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average branch length of vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Ratio of CD45+ vg5- MHC II- cells/vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Rod a-wave implicit time-left
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / B2 t3 + f1+ f2 + gc cells - IMPC panel cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector gd T cells - % of gd T cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of cervical vertebrae
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Eyelid closure
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Eyelid closure
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair colour
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
0.0287
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / B1a cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / CD103+ CD11b-low cDC - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Tail bud morphology
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair colour pattern
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Aspartate aminotransferase
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.437
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Aspartate aminotransferase
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.464
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector Treg cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - length
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Hindbrain morphology
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 average roundness of vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Late germinal centre B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting NK cells - % of NK cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / B cell panel live cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average roundness of vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting CD4- NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Syndactylism
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Syndactylism
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Plasma cells - % of B2 cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Teeth presence
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Cytotoxic T cell function / 2.5:1 stdev
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average volume of vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Ly6C+ NKT cells - % of lymphocytes
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Rotarod / Latency to fall
|
HET
|
40f:40m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forelimb morphology
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / CD103+ CD11b-low cDC - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total CD4+ T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Narrow eye opening
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Narrow eye opening
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / CD11b-low cDC - % of cDC
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Glycerol
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00422
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Pre-B cells (Hardy fraction D) - % of B220+
|
HET
|
3f:1m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting CD4+ NKT cells - % of CD4+ NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Memory B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Vibrissae colour
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 average no of branches on LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average volume of vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Lung
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Lung
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Lung
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw footpad size
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00196
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting gd T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total NK cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Monocytes - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting CD8+ T cells - % of CD8+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total myeloid cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroconvulsive Threshold Testing / Comment
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 ratio of contacting/not contacting vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total Treg cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total gd T cells - % of total T cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Naive CD8+ T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Plasma cells - % of CD45+
|
HET
|
3f:1m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Snout size
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / Click-evoked ABR threshold
|
HET
|
f:4m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0787
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Synechia
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Synechia
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Total cholesterol
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0360
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total cholesterol
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.381
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Light side time spent
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0103
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Cholesterol ratio
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.388
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Monocyte percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Monocyte percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.543
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.888
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electrocardiogram (ECG) / HR
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.861
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Delayed embryonic development
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / T cell panel live cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Pelvis
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Pelvis
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.308
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Early germinal centre B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / B2 t1 + t2 cells - IMPC panel cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total CD4- NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average no of branches on LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Viability E9.5 Secondary Screen / Outcome
|
HOM
|
f:m
|
Supplied as data
|
0.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Viability E9.5 Secondary Screen / Outcome
|
HOM
|
f:m
|
Supplied as data
|
0.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Shape of spine
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Shape of spine
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Eyelid morphology
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Eyelid morphology
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / T cell panel singlets cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Spleen
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Type of gd T cell
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / CD11b-low cDC - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total ab T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindpaw - size
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb grip strength measurement
|
HET
|
27f:21m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HET
|
24f:24m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total ab T cells - % of total T cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / CD11b-high cDC - % of cDC
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Positional passivity
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average roundness of vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Myeloid cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Lower Urinary Tract
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair colour pattern
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
0.0287
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair length
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Cytotoxic T cell function / 5:1 stdev
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0320
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting CD4- NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Early germinal centre B cells - % of GC cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total CD8+ T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD4+ NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Uterus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector CD4+ NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Ly6C+ immature NK cells - % of immature NK cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Rod a-wave amplitude-right
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average volume of LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average branch length of vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Mouth morphology
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Late germinal centre B cells - % of B2 cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Granulocytes - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin color - whole body
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector CD4+ NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Tail Morphology
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of digits
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Pro-B cells (Hardy fractions B and C) - % of B220+
|
HET
|
3f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Comment
|
HET
|
f:m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dysmorphology comment
|
HET
|
4f:4m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Rotarod / Average duration
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.891
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Total T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Total T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD8+ T cells - % of CD8+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Conventional DC (cDC) - % of DC
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Average histology score
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair presence
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Incisors
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 ratio of contacting/not contacting vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Brainstem
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 average no of branches on vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - head
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw size
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Midbrain
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Side changes
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.000221
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alkaline phosphatase
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0907
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Alkaline phosphatase
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.406
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Eye Hemorrhage or Blood Presence
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Eye Hemorrhage or Blood Presence
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - shape
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Immature NK cells - % of NK cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.534
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Cytotoxic T cell function / 10:1 stdev
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Body Weight / Body weight
|
HET
|
120f:116m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Body Weight / Body weight
|
HET
|
83f:84m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Fusion between cornea and lens
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Fusion between cornea and lens
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair presence
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw size
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0329
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.542
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electrocardiogram (ECG) / CV
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.946
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Forepaw - size
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Somite Morphology
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Fusion of ribs
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Fusion of ribs
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / T cells - % of CD45+
|
HET
|
3f:1m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb grasping
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Conventional DC (cDC) - % of DC
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting CD8+ T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / B2 marginal zone + precursor cells - IMPC panel cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ gd T cells - % of gd T cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Pallor
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair appearance
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Plasma cells - cell count
|
HET
|
3f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 count of vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Body Weight / General comments about the mouse
|
HET
|
24f:20m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Germinal centre B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / CD11b-high cDC - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Joints
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Joints
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Large Intestine
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HET
|
24f:24m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HET
|
27f:21m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ Treg cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Myeloid panel singlets cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Red blood cell distribution width
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00742
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Ears
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total CD4+ NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 average volume of vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Brain
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total CD4+ NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Granulocytes + monocytes - % of CD45+
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average no of branches on LC
|
HET
|
2f:2m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Rotarod / Learning difference
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.130
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector CD4- NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Total section 2 score
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Pro-B cells (Hardy fraction B) - % of B220+
|
HET
|
3f:1m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Ly6C+ CD5+ T cells - IMPC panel cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Early germinal centre B cells - % of B2 cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total Treg cells - % of CD4+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / B2 t3 + f1+ f2 + gc cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Rod a-wave amplitude-left
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector gd cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HET
|
232f:257m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average volume of LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Bulging eye
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Bulging eye
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total CD4+ NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Mature NK cells - IMPC panel cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / B cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / B cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total B2 cells - IMPC panel cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / NKT cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / NKT cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Pre-pro B cells (Hardy fraction A) - % of B220+
|
HET
|
3f:1m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting CD4- NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ CD4+ NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ Treg cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Iris/Pupil
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Iris/Pupil
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average no of branches on vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Cartilage tissue
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Striatum
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total gd T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Heart Weight / Heart weight normalised against body weight
|
HET
|
7f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Heart Weight / Heart weight normalised against body weight
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Corneal deposits
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Total food intake
|
HET
|
f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0154
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Fibula
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Fibula
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Shape of vertebrae
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Shape of vertebrae
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Naive CD8+ T cells - % of CD8+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Body Composition (DEXA lean/fat) / Body length
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Body length
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.343
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Cone b-wave implicit time-right
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ gd T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Small Intestine
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Cytotoxic T cell function / % lysis
|
HET
|
12f:12m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Midbrain
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Transitional 2 B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Ly6C+ mature NK cells - % of mature NK cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average roundness of vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimbs - shape
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Thalamus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Lymph Node
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw morphology
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector CD4+ T helper cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Follicular B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ Treg cells - % of Treg
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head skin colour
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair length
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Tail Suspension / Latency to immobility
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.482
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair colour pattern
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair length
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / CD4+ T helper cells - % of CD4+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 tissue volume
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Count of vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average volume of vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Blebs
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.105
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HET
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.172
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - number
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Macrophages - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Body weight
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Body weight
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.193
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.788
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Myeloid panel singlets cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail length
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average no of branches on vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Potassium
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.000690
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Potassium
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.407
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0383
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total CD4- NKT cells - % of NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Phosphorus
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0444
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Phosphorus
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.103
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total DC - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindpaw - shape
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average branch length of vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / B2 t1 + t2 cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Rod b-wave implicit time-right
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Plasmacytoid DC - % of DC
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 average roundness of LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Head morphology
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw nail colour
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electrocardiogram (ECG) / ST
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.305
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Respiratory Exchange Ratio
|
HET
|
f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair colour pattern
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / B1a cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting CD8+ T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.593
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average no of branches on vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Follicular B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Follicular B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Center average speed
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.442
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting gd T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting CD4+ T helper cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Transitional 1 B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Cumulative food intake
|
HET
|
f:155m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Thymus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Ly6C+ mature NK cells - IMPC panel cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Skeletal Muscle
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total B cells - IMPC panel cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Pupil Position
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Pupil Position
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average volume of LC
|
HET
|
2f:2m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ CD8+ T cells - % of CD8+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electrocardiogram (ECG) / pNN5(6>ms)
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimbs - size
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Early germinal centre B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Mammary gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Fusion of vertebrae
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Fusion of vertebrae
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Plasmacytoid DC - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Tibia
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Tibia
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Iris transilumination
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Touch escape
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Tail Suspension / Time immobile
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.564
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head skin appearance
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting Treg cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector CD4- NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw footpad skin appearance
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Optic vesicle morphology
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total CD4+ T cells - % of ab T cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Rod b-wave amplitude-left
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair appearance
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / B2 t3 + f1+ f2 + gc cells - % of lymphocytes
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Count of vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting gd T cells - % of gd T cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electrocardiogram (ECG) / QTc
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HET
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000474
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0101
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Head size
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average no of branches on vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail morphology
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting CD4+ T helper cells - % of CD4+ T helper cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Sodium
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0218
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Sodium
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.871
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Forepaw - shape
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Alive
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Alive
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair colour
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Germinal centre B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.124
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
1.98×10-07
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Ly6C+ NKT cells - % of NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Corneal touch reflex
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / CD11b-low cDC - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / B2 marginal zone + precursor cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Delayed embryonic development
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Cone b-wave implicit time-left
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average no of branches on vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Limb Bud Morphology
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw nail morphology
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Plasmacytoid DC - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Trachea
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Granulocytes + monocytes - % of CD45+
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector CD8+ T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.126
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Cerebral Cortex
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector NK cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Eye
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting CD4+ NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Cytotoxic T cell function / Target cell
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average branch length of vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total DC - % of myeloid cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Transitional 2 B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Viability E12.5 Secondary Screen / Outcome
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Ear Morphology
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Testis
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector CD4- NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Conventional DC (cDC) - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Kidney
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Naive CD8+ T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindlimb
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total B2 cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Pituitary gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Center permanence time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.863
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total CD4+ NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of ribs right
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electrocardiogram (ECG) / rMSSD
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.850
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Retina
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retina
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting CD4+ NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Whole arena permanence
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electrocardiogram (ECG) / PR
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.812
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ gd T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Iron
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0952
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Iron
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.122
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Magnesium
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00219
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 average roundness of vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Marginal zone precursor B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimb nail - length
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Forebrain morphology
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ T helper cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / B2 marginal zone + precursor cells - % of B2 cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 count of vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Monocyte number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Monocyte number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector CD4+ T helper cells - % of CD4+ T helper cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Immature NK cells - IMPC panel cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Urinary bladder
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average roundness of LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Aggression
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector Treg cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / CD103+ CD11b-low cDC - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw digit fusion
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Comment
|
HET
|
f:m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector NK cells - % of NK cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Startle response
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting Treg cells - % of Treg
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / T cell panel live cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair appearance
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total gd T cells - % of total T cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair appearance
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Total section 1 score
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average no of branches on vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Femur
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Femur
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting CD4+ NKT cells - % of CD4+ NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector CD4+ T helper cells - % of CD4+ T helper cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.203
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
2.79×10-06
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Follicular B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Heart looping
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna position
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hematology / Red blood cell count
|
HET
|
3f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000835
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Red blood cell count
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.798
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hematology / Red blood cell count
|
HET
|
3f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.803
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair colour
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw digit count
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting gd T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Vibrissae - appearance
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Mature NK cells - % of lymphocytes
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw footpad skin colour
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector NK cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Granulocytes - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 average no of branches on vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Startle response
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Eosinophils - % of myeloid cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Cytotoxic T cell function / % CD8+
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector CD8+ T cells - % of CD8+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / CD4+ T helper cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Ratio of vg5+ DETC/LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Conventional DC (cDC) - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average volume of CD45+ vg5- MHC II- cells
|
HET
|
1f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / NK cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / NK cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Cerebellum
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0691
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HET
|
6f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.466
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - head
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / CD11b-high cDC - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / CD5+ gd T cells - % of gd T cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electrocardiogram (ECG) / Mean R amplitude
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4- NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ NK cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of lumbar vertebrae
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Myeloid panel live cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector CD4+ NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Ulna
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Ulna
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / CD11b-high cDC - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting CD4- NKT cells - % of CD4- NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average roundness of vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Buffers and enzymes
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD8+ T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - number
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hole-board Exploration / Total holepokes
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.372
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair presence
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of caudal vertebrae
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average roundness of LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / NK cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / NK cell percentage
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0375
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of ribs left
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total NK cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw nail colour
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair length
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Transitional 1 B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / IMPC panel singlets cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total NK cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.736
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Vascular System
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Retinal Pigmentation
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retinal Pigmentation
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Marginal zone B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Liver
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average roundness of LC
|
HET
|
2f:2m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Stomach
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total CD4- NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimbs - position
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting CD4+ T helper cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw digit morphology
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting CD4+ T helper cells - % of CD4+ T helper cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Ly6C+ immature NK cells - IMPC panel cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / B2 t1 + t2 cells - % of B2 cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Cone b-wave amplitude-left
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / T cell panel CD45+ live cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair presence
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna morphology
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw digit size
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average volume of vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Cone b-wave amplitude-right
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Transitional 2 B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Section 2 Severe Markers
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Hippocampus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD4+ NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Marginal zone precursor B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Monocytes - % of myeloid cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimb nail - number
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total CD8+ T cells - % of ab T cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Cytotoxic T cell function / % CD4+
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Chorioallantoic fusion
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electrocardiogram (ECG) / QRS
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.892
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Langerhans cell (LC) count
|
HET
|
2f:2m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair colour
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 count of vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Chloride
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00427
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Chloride
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.983
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Insulin Blood Level / Insulin
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.455
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Insulin Blood Level / Insulin
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.863
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Ly6C+ mature NK cells - % of lymphocytes
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting NK cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.155
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Granulocytes - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Lean mass
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
1.93×10-09
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Body Composition (DEXA lean/fat) / Lean mass
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.781
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector CD4- NKT cells - % of CD4- NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Ly6C+ CD5+ T cells - % of lymphocytes
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of pelvic vertebrae
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Monocytes - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average no of branches on vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimb digit - number
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tremor
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / White blood cell count
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00808
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hematology / White blood cell count
|
HET
|
3f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.503
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hematology / White blood cell count
|
HET
|
3f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.780
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Marginal zone B cells - % of B2 cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Total B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimb digit - size
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Ophthalmoscope Observation
|
HET
|
1f:m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average roundness of vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Eye size-left
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin texture - whole body
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / BM panel lymphocyte gate cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Creatinine
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0259
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Heart looping
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair appearance
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Blind-right
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / T cell panel lymphocyte gate cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD4- NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Myeloid panel live cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average branch length of LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / B1a cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Radius
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Radius
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Memory B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Mean platelet volume
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.472
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average no of branches on vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 average branch length of vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Number of Rears
|
HET
|
32f:32m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Brachydactyly
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Brachydactyly
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total gd T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Late germinal centre B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Scapulae
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Scapulae
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.00938
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw nail morphology
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Pericardium Morphology
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total CD4- NKT cells - % of NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw digit fusion
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Naive CD8+ T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Vg5+ dendritic epidermal T cell (DETC) count
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Retinal Structure
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retinal Structure
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 vg5+ DETC count
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Skin
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / T cell panel CD45+ live cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Immature NK cells - % of lymphocytes
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retina (combined)
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.714
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Retina (combined)
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
0.759
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Heart Weight / Body weight
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Heart Weight / Body weight
|
HET
|
7f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Spleen
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Spleen
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Spleen
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Pancreas
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Granulocytes - % of myeloid cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Polysyndactylism
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Polysyndactylism
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Visceral yolk sac morphology
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average roundness of CD45+ vg5- MHC II- cells
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 ratio of vg5+ DETC/LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hematology / Hematocrit
|
HET
|
3f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00180
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Hematocrit
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.783
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hematology / Hematocrit
|
HET
|
3f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.823
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Embryo turning
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Blind-left
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average volume of vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Granulocytes + monocytes - % of myeloid cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Immature B cells (Hardy fraction E) - % of CD45+
|
HET
|
3f:1m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector CD8+ T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - color - abdomen
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Section 2 Area
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Hypothalamus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Late germinal centre B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Pupil Dilation
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
0.0626
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Pupil Dilation
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Facial cleft
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair appearance
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Pre-pro B cells (Hardy fraction A) - cell count
|
HET
|
3f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Tremor
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ Treg cells - % of Treg
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Marginal zone precursor B cells - % of B2 cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total Treg cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Brain
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Brain
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Brain
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Total water intake
|
HET
|
f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.718
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ NK cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal skin colour
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 count of vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Carbon dioxide production
|
HET
|
f:63m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Body Weight
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Body Weight
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Auditory Brain Stem Response / 18kHz-evoked ABR Threshold
|
HET
|
4f:4m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0281
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / 18kHz-evoked ABR Threshold
|
HET
|
f:4m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Percent time in dark
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00600
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / CD103+ CD11b-low cDC - % of CD11b-low cDC
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electrocardiogram (ECG) / Mean SR amplitude
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Thyroid gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Clavicle
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Clavicle
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Body Weight / Body weight curve
|
HET
|
145f:141m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Body Weight / Body weight curve
|
HET
|
106f:123m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total Treg cells - % of CD4+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / B cell panel live cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 count of vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Eye size-right
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 average branch length of vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / B cell panel CD45+ live cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Mature B cells (Hardy fraction F) - cell count
|
HET
|
3f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - size
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector CD4- NKT cells - % of CD4- NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting CD4+ T helper cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average roundness of vg5+ DETC not contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Digit integrity
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Digit integrity
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Marginal zone precursor B cells - % of B2 cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total CD4+ NKT cells - % of NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw nail length
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin texture - snout
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Total protein
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00272
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total protein
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.853
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.451
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.983
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour pattern
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / B cell panel lymphocyte gate cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total B2 cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Pale yolk sac
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 average volume of vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ CD8+ T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Oviduct
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Pre-B cells (Hardy fraction D) - % of CD45+
|
HET
|
3f:1m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ gd T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 vg5+ DETC count
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Distance travelled
|
HET
|
32f:32m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Section 1 Epithelium
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / CD45+ vg5- MHC II- cell count
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw digit morphology
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / BM panel CD45+ cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Placenta E9.5 / Placenta Size
|
HET
|
12f:10m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average branch length of vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / CD5+ gd T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hematology / Hemoglobin
|
HET
|
3f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.00154
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Hemoglobin
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.112
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hematology / Hemoglobin
|
HET
|
3f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.398
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Ly6C+ immature NK cells - % of lymphocytes
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Aorta
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Plasma cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Heat production (metabolic rate)
|
HET
|
f:63m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Total T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Total T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Vitreous
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Neural tube closure
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total ab T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Placenta E9.5 / Umbilical cord morphology
|
HET
|
12f:10m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector gd cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 ratio of vg5+ DETC/LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Optic Disc
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Optic Disc
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - back
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Pro-B cells (Hardy fractions B and C) - cell count
|
HET
|
3f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting CD8+ T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total NK cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Heart Weight / Heart weight
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0154
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Heart Weight / Heart weight
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.778
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Vibrissae size
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total NK cells - IMPC panel cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average roundness of CD45+ vg5- MHC II- cells
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting gd T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal skin appearance
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / B2 marginal zone + precursor cells - % of lymphocytes
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Section 2 Lamina Propria
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.575
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Pupil Shape
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Pupil Shape
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HET
|
35f:35m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HET
|
40f:40m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electrocardiogram (ECG) / QTc Dispersion
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Cervical processes
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Cervical processes
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.0276
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector NK cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total CD8+ T cells - % of ab T cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Plasma cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector CD4+ NKT cells - % of CD4+ NKT cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Head shape
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Pancreas
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Pancreas
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Pancreas
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector CD4+ T helper cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair colour pattern
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Comment on XRay image
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Comment on XRay image
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Germinal centre B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw nail count
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Section 1 Lamina Propria
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Percent time in light
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00600
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Spinal cord
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Spinal cord
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Spinal cord
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Abdominal wall
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 LC count
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.420
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
6.46×10-06
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Tissue volume
|
HET
|
2f:m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average no of branches on vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ CD4+ T helper cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting NK cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Germinal centre B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Auditory Brain Stem Response / 24kHz-evoked ABR Threshold
|
HET
|
4f:4m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0462
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / 24kHz-evoked ABR Threshold
|
HET
|
f:4m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Myeloid panel CD45+ live cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Immature B cells (Hardy fraction E) - cell count
|
HET
|
3f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 vg5+ DETC count
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Albumin
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00505
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Albumin
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0447
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Transitional vertebrae
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Transitional vertebrae
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F1 average volume of CD45+ vg5- MHC II- cells
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Hemorrhage
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Late germinal centre B cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Lung
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna rotation
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Myeloid panel lymphocyte gate cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total ab T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector CD4+ NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average roundness of vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Mean cell volume
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hematology / Mean cell volume
|
HET
|
3f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.723
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hematology / Mean cell volume
|
HET
|
3f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.995
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - color - back
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimb digit - shape
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Pro-B cells (Hardy fraction C) - % of CD45+
|
HET
|
3f:1m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Pro-B cells (Hardy fraction B) - cell count
|
HET
|
3f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector CD8+ T cells - % of CD8+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Monocytes - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total myeloid cells - % of CD45+
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average roundness of vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total B2 cells - % of B cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Upper lip morphology
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HET
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.122
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 average branch length of vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna skin colour
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Effector NK cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ gd T cells - % of gd T cells
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw nail length
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Ambulatory activity (no. of beam cuts)
|
HET
|
f:155m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Macrophages - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Ovary
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Forebrain
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total CD4+ T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electrocardiogram (ECG) / HRV
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.913
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Retinal Blood Vessels
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retinal Blood Vessels
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Section 2 Epithelium
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Naive CD8+ T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Pale Liver
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total gd T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / B1a cells - % of B cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Mandibles
|
HET
|
7f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Mandibles
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Vibrissae
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
0.0809
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Edema
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna touch reflex
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair presence
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin color - back paws
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Effector Treg cells - % of Treg
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Anti-nuclear antibody assay / ANA score
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Anti-nuclear antibody assay / ANA score
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting NK cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ NK cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / B2 t3 + f1 + f2 + gc cells - % of B2 cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total NKT cells - IMPC panel cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Pro-B cells (Hardy fraction B) - % of CD45+
|
HET
|
3f:1m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Plasma cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Fructosamine
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.415
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Corneal Sclerization
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Anti-nuclear antibody assay / ANA classification
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Anti-nuclear antibody assay / ANA classification
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / IMPC panel live cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Early germinal centre B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Teeth
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Teeth
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Section 1 Area
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Vitelline vasculature morphology
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 average no of branches on vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair length
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Craniofacial morphology
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Heart morphology
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Submandibular Gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / CD4+ T helper cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / White Adipose Tissue
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Total NKT cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Early germinal centre B cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 LC count
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / DETC coverage
|
HET
|
2f:2m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - color - head
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Mean corpuscular hemoglobin
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0397
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hematology / Mean corpuscular hemoglobin
|
HET
|
3f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.655
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Hematology / Mean corpuscular hemoglobin
|
HET
|
3f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.937
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total CD4+ T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total Treg cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / KLRG1+ NK cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Bone marrow immunophenotyping / Pre-B cells (Hardy fraction D) - cell count
|
HET
|
3f:1m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - shape
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Total bilirubin
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.430
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total bilirubin
|
HET
|
6f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.511
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HET
|
f:155m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / Average roundness of CD45+ vg5- MHC II- cells
|
HET
|
1f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / 3i T cell panel
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Body Composition (DEXA lean/fat) / BMC/Body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.420
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / BMC/Body weight
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.452
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Lower lip morphology
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting NK cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Adult LacZ / Brown adipose tissue
|
HET
|
1f:1m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F2 tissue volume
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Resting CD4+ NKT cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw nail count
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil number
|
HET
|
7f:7m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 average branch length of vg5+ DETC contacting LC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Retinal Blood Vessels Structure
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retinal Blood Vessels Structure
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Resting CD8+ T cells - % of CD8+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Macrophages - % of myeloid cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Eosinophils - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Tail Suspension / Climbing
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / Marginal zone B cells - % of B2 cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna skin appearance
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Gait
|
HET
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
X-ray / Fusion of processes
|
HET
|
5f:5m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Fusion of processes
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.263
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Kidney
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Kidney
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Kidney
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Snout size
|
HET
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Electroretinography 2 / Rod b-wave implicit time-left
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / T cell panel lymphocyte gate cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E9.5 / Otic vesicle morphology
|
HET
|
12f:9m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Section 1 Severe Markers
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / CD5+ gd T cells - % of CD45+
|
HET
|
3f:3m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD8+ T cells - cell count
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Spleen Immunophenotyping / Total B2 cells - % of B cells
|
HET
|
3f:3m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Ear epidermis immunophenotyping / F3 average roundness of vg5+ DETC
|
HET
|
2f:2m
|
|
|
NotProcessed |
Orc1tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair length
|
HET
|
9f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin color - tail
|
HET
|
8f:7m
|
|
|
NotProcessed |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Hemorrhage
|
HET
|
6f:5m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Orc1tm1b(KOMP)Wtsi
|
JAX
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |