Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Whole arena resting time series
|
HOM
|
48f:56m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Center distance travelled series
|
HOM
|
48f:56m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Context freezing total
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00520
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
13f:15m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration cue-2
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Whole arena average speed series
|
HOM
|
24f:32m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Center resting time series
|
HOM
|
24f:32m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
3f:3m
|
Fisher Exact Test framework
|
0.197
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Periphery resting time series
|
HOM
|
24f:32m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Distance travelled - total
|
HOM
|
6f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.428
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Center average speed series
|
HOM
|
24f:31m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Pre-cue freezing total
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.119
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Periphery permanence time
|
HOM
|
6f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0164
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Periphery resting time
|
HOM
|
12f:14m
|
Linear Mixed Model framework, LME, including Weight
|
0.0238
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0318
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Rotarod / Latency to fall
|
HOM
|
21f:21m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Percentage center movement time
|
HOM
|
12f:14m
|
Linear Mixed Model framework, LME, including Weight
|
0.00727
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Percentage center movement time
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.352
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00121
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
13f:15m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Percentage center time
|
HOM
|
6f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0198
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
13f:15m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Center permanence time series
|
HOM
|
48f:56m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Center permanence time
|
HOM
|
12f:14m
|
Linear Mixed Model framework, LME, including Weight
|
0.0338
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
12f:13m
|
Linear Mixed Model framework, LME, not including Weight
|
0.233
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Number of center entries
|
HOM
|
6f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.198
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration post-us
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Periphery distance travelled series
|
HOM
|
48f:56m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.865
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Latency to center entry
|
HOM
|
12f:14m
|
Linear Mixed Model framework, LME, not including Weight
|
0.835
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery average speed
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00252
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Distance travelled
|
HOM
|
48f:56m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.000427
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Periphery distance travelled
|
HOM
|
6f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.247
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
13f:15m
|
Fisher Exact Test framework
|
0.255
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Center permanence time
|
HOM
|
6f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0198
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Center distance travelled
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.294
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Eye Morphology / Pupil Light Response
|
HOM
|
12f:13m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.000258
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
24f:24m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
13f:15m
|
Fisher Exact Test framework
|
0.00186
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Percentage center time
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00506
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Rotarod / Passive rotation
|
HOM
|
21f:21m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
12f:13m
|
Linear Mixed Model framework, LME, including Weight
|
0.0439
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration pre-cue-1
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.990
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Context freezing total
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00550
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Percentage center movement time
|
HOM
|
6f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0256
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0286
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Periphery permanence time series
|
HOM
|
24f:32m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Whole arena resting time
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0112
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.341
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Whole arena resting time
|
HOM
|
12f:14m
|
Linear Mixed Model framework, LME, including Weight
|
0.0753
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Indirect Calorimetry / Ambulatory activity (no. of beam cuts)
|
HOM
|
f:614m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Center permanence time
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00506
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Center resting time
|
HOM
|
12f:14m
|
Linear Mixed Model framework, LME, not including Weight
|
0.108
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.783
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Eye Morphology / Optic Disc
|
HOM
|
12f:13m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration cue
|
HOM
|
14f:14m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
36f:39m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
21f:21m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.808
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
12f:13m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0961
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Hot Plate / Type of response
|
HOM
|
7f:6m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery resting time
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.547
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
0.000629
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
13f:15m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-2
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.126
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Periphery average speed
|
HOM
|
12f:14m
|
Linear Mixed Model framework, LME, including Weight
|
0.000161
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Periphery average speed series
|
HOM
|
48f:56m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
13f:15m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Center distance travelled
|
HOM
|
6f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.142
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Whole arena average speed
|
HOM
|
12f:14m
|
Linear Mixed Model framework, LME, including Weight
|
0.000119
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Center distance travelled series
|
HOM
|
24f:32m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Distance travelled
|
HOM
|
28f:28m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Whole arena resting time series
|
HOM
|
24f:32m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Latency to center entry
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.163
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Number of center entries
|
HOM
|
12f:14m
|
Linear Mixed Model framework, LME, including Weight
|
0.00146
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Periphery resting time
|
HOM
|
6f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0531
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Number of center entries
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.316
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
3f:3m
|
Fisher Exact Test framework
|
0.580
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Center permanence time series
|
HOM
|
24f:32m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
13f:15m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Periphery distance travelled
|
HOM
|
12f:14m
|
Linear Mixed Model framework, LME, including Weight
|
0.000516
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.000926
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration context
|
HOM
|
21f:21m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Whole arena average speed series
|
HOM
|
48f:56m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Center resting time series
|
HOM
|
48f:56m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration cue-1
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Periphery distance travelled series
|
HOM
|
24f:32m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Distance travelled
|
HOM
|
24f:32m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Distance travelled - total
|
HOM
|
12f:14m
|
Linear Mixed Model framework, LME, including Weight
|
0.000107
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Distance travelled - total
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.000680
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration habituation-1
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.204
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Latency to center entry
|
HOM
|
6f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.547
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery permanence time
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00506
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Center average speed series
|
HOM
|
48f:55m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Cue freezing total
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00554
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.000222
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.182
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Rotarod / Latency to fall mean
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0149
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
13f:15m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Indirect Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HOM
|
f:614m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
13f:15m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Periphery resting time series
|
HOM
|
48f:56m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration habituation
|
HOM
|
14f:14m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Whole arena average speed
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.000227
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Center average speed
|
HOM
|
12f:14m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0143
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Percentage center time
|
HOM
|
12f:14m
|
Linear Mixed Model framework, LME, including Weight
|
0.0338
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
12f:13m
|
Linear Mixed Model framework, LME, including Weight
|
0.00966
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0201
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Number of Rears
|
HOM
|
28f:28m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
1.72×10-07
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Whole arena resting time
|
HOM
|
6f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0510
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.352
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Center resting time
|
HOM
|
6f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0243
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Center resting time
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.105
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Center distance travelled
|
HOM
|
12f:14m
|
Linear Mixed Model framework, LME, including Weight
|
0.000986
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Eye Morphology / Optic Disc
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Center average speed
|
HOM
|
6f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0105
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration habituation-2
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.158
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
36f:39m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
13f:13m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000777
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Number of rears - total
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.172
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
24f:24m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
3f:3m
|
Fisher Exact Test framework
|
0.0133
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Hot Plate / Hot plate latency
|
HOM
|
7f:6m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.51×10-11
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-3
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0400
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
13f:15m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Periphery average speed series
|
HOM
|
24f:32m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Periphery permanence time series
|
HOM
|
48f:56m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.253
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.214
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Center average speed
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00459
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Periphery permanence time
|
HOM
|
12f:14m
|
Linear Mixed Model framework, LME, including Weight
|
0.0319
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Periphery average speed
|
HOM
|
6f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0850
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
3f:3m
|
Fisher Exact Test framework
|
0.00233
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00697
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Eye Morphology / Pupil Light Response
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
21f:21m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Open Field / Whole arena average speed
|
HOM
|
6f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.428
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration pre-cue
|
HOM
|
14f:14m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
13f:15m
|
|
|
NotProcessed |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration pre-cue-2
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0249
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery distance travelled
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.353
|
Successful |
Sorl1tm1a(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-1
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00110
|
Successful |
Sorl1tm1b(EUCOMM)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
13f:15m
|
Fisher Exact Test framework
|
1.00
|
Successful |