All nervous system phenotype, behavior/neurological phenotype data for Acvr2a

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status Graph
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Periphery resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.42687 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Periphery resting time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.42687 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Center permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0055642 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Center permanence time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0055642 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Whole arena resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.92052 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Whole arena resting time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.92052 Success
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Activity (body position) HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Activity (body position) HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Activity (body position) HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Activity (body position) HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Head bobbing HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Head bobbing HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Head bobbing HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Head bobbing HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Trunk curl HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Trunk curl HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Trunk curl HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Trunk curl HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Center resting time HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.00047799 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Center resting time HET 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.00047799 Success
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Locomotor activity HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.88518 Success
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Locomotor activity HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.88518 Success
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Locomotor activity HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.88518 Success
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Locomotor activity HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.88518 Success
Acvr2atm1.1(KOMP)Vlcg TCP Eye Morphology / Optic Disc HET 7f:7m Fisher Exact Test framework 1.0000 Success
Acvr2atm1.1(KOMP)Vlcg TCP Eye Morphology / Optic Disc HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Acvr2atm1.1(KOMP)Vlcg TCP Eye Morphology / Optic Disc HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Acvr2atm1.1(KOMP)Vlcg TCP Eye Morphology / Optic Disc HET 7f:7m Fisher Exact Test framework 1.0000 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Center average speed HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.024121 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Center average speed HET 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.024121 Success
Acvr2atm1.1(KOMP)Vlcg TCP Gross Morphology Embryo E12.5 / Midbrain morphology HET f:m Supplied as data Success
Acvr2atm1.1(KOMP)Vlcg TCP Gross Morphology Embryo E12.5 / Midbrain morphology HET f:m Supplied as data Success
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Contact righting HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Contact righting HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Contact righting HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Contact righting HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Distance travelled - total HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.47732 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Distance travelled - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.47732 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Number of rears - total HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.75206 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Number of rears - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.75206 Success
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Unexpected behaviors HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Unexpected behaviors HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HET 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0026416 Success
Acvr2atm1.1(KOMP)Vlcg TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0026416 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Periphery permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0055638 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Periphery permanence time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0055638 Success
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Gait HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Gait HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Gait HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Gait HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Gross Morphology Embryo E12.5 / Neural Tube Closure HET f:m Supplied as data Success
Acvr2atm1.1(KOMP)Vlcg TCP Gross Morphology Embryo E12.5 / Neural Tube Closure HET f:m Supplied as data Success
Acvr2atm1.1(KOMP)Vlcg TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HET 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.16073 Success
Acvr2atm1.1(KOMP)Vlcg TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.16073 Success
Acvr2atm1.1(KOMP)Vlcg TCP Gross Morphology Embryo E12.5 / Forebrain morphology HET f:m Supplied as data Success
Acvr2atm1.1(KOMP)Vlcg TCP Gross Morphology Embryo E12.5 / Forebrain morphology HET f:m Supplied as data Success
Acvr2atm1.1(KOMP)Vlcg TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0011342 Success
Acvr2atm1.1(KOMP)Vlcg TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HET 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0011342 Success
Acvr2atm1.1(KOMP)Vlcg TCP Indirect Calorimetry / Total food intake HET 8f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.25086 Success
Acvr2atm1.1(KOMP)Vlcg TCP Indirect Calorimetry / Total food intake HOM 8f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.25086 Success
Acvr2atm1.1(KOMP)Vlcg TCP Indirect Calorimetry / Total food intake HET 8f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.25086 Success
Acvr2atm1.1(KOMP)Vlcg TCP Indirect Calorimetry / Total food intake HOM 8f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.25086 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Latency to center entry HET 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.065299 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Latency to center entry HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.065299 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Percentage center time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0055643 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Percentage center time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0055643 Success
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Aggression HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Aggression HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Aggression HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Aggression HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Number of center entries HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.86458 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Number of center entries HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.86458 Success
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Tremor HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Tremor HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Tremor HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Tremor HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HET 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.014325 Success
Acvr2atm1.1(KOMP)Vlcg TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.014325 Success
Acvr2atm1.1(KOMP)Vlcg TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.45193 Success
Acvr2atm1.1(KOMP)Vlcg TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.45193 Success
Acvr2atm1.1(KOMP)Vlcg TCP Grip Strength / Forelimb grip strength measurement mean HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.11731 Success
Acvr2atm1.1(KOMP)Vlcg TCP Grip Strength / Forelimb grip strength measurement mean HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.11731 Success
Acvr2atm1.1(KOMP)Vlcg TCP Grip Strength / Forelimb grip strength measurement mean HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.11731 Success
Acvr2atm1.1(KOMP)Vlcg TCP Grip Strength / Forelimb grip strength measurement mean HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.11731 Success
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Startle response HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Startle response HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Startle response HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Startle response HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Periphery average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.070609 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Periphery average speed HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.070609 Success
Acvr2atm1.1(KOMP)Vlcg TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HET 8f:8m Mixed Model framework, generalized least squares, equation withWeight 0.14444 Success
Acvr2atm1.1(KOMP)Vlcg TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 8f:8m Mixed Model framework, generalized least squares, equation withWeight 0.14444 Success
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Limb grasp HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Limb grasp HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Limb grasp HET 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Limb grasp HOM 7f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Acvr2atm1.1(KOMP)Vlcg TCP Eye Morphology / Pupil Light Response HET 7f:7m Fisher Exact Test framework 1.0000 Success
Acvr2atm1.1(KOMP)Vlcg TCP Eye Morphology / Pupil Light Response HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Acvr2atm1.1(KOMP)Vlcg TCP Eye Morphology / Pupil Light Response HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Acvr2atm1.1(KOMP)Vlcg TCP Eye Morphology / Pupil Light Response HET 7f:7m Fisher Exact Test framework 1.0000 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Whole arena average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.12259 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Whole arena average speed HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.12259 Success
Acvr2atm1.1(KOMP)Vlcg TCP Gross Morphology Embryo E12.5 / Hindbrain morphology HET f:m Supplied as data Success
Acvr2atm1.1(KOMP)Vlcg TCP Gross Morphology Embryo E12.5 / Hindbrain morphology HET f:m Supplied as data Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Center distance travelled HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.60280 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Center distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.60280 Success
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Vocalization HET 7f:8m Fisher Exact Test framework 1.0000 Success
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Vocalization HOM 7f:8m Fisher Exact Test framework 1.0000 Success
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Vocalization HET 7f:8m Fisher Exact Test framework 1.0000 Success
Acvr2atm1.1(KOMP)Vlcg TCP Combined SHIRPA and Dysmorphology / Vocalization HOM 7f:8m Fisher Exact Test framework 1.0000 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Periphery distance travelled HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.075161 Success
Acvr2atm1.1(KOMP)Vlcg TCP Open Field / Periphery distance travelled HET 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.075161 Success
Acvr2atm1.1(KOMP)Vlcg TCP Grip Strength / Forelimb and hindlimb grip strength measurement mean HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.76214 Success
Acvr2atm1.1(KOMP)Vlcg TCP Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.76214 Success
Acvr2atm1.1(KOMP)Vlcg TCP Grip Strength / Forelimb and hindlimb grip strength measurement mean HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.76214 Success
Acvr2atm1.1(KOMP)Vlcg TCP Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.76214 Success

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