Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw footpad size
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Epididymis
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Alanine aminotransferase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.638
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Echo / LVPWd
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.418
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / External genitalia morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / B cell number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / NKT cell number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Left Adrenal gland
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Brain
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Creatinine
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.558
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair appearance
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Snout morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Hematology / Mean cell hemoglobin concentration
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0297
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Mean cell hemoglobin concentration
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.132
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Eyelid Opening
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Body Weight
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Incisors morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / NKT cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Eosinophil differential count
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
1.74×10-09
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Hematology / Mean platelet volume
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
9.70×10-09
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Mean platelet volume
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.000788
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Percentage center time
|
HOM
|
10f:12m
|
Linear Mixed Model framework, LME, not including Weight
|
0.688
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Auditory Brain Stem Response / 6kHz-evoked ABR Threshold
|
HOM
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0627
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Echo / LVAWs
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.855
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Right Adrenal gland
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Body Composition (DEXA lean/fat) / Body length
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00587
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Body length
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0842
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Pancreas
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail skin appearance
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw nail morphology
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb skin appearance
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair presence
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw digit fusion
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / LDL-cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0405
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Uterus
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Periphery distance travelled
|
HOM
|
10f:12m
|
Linear Mixed Model framework, LME, including Weight
|
6.86×10-05
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindlimb size
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw morphology
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Heart Weight / Body weight
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head skin colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Calcium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0207
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Echo / HR
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.344
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair colour pattern
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Percentage center movement time
|
HOM
|
10f:12m
|
Linear Mixed Model framework, LME, not including Weight
|
0.530
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna size
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Thymus
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Hematocrit
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0263
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Hematology / Hematocrit
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.587
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Vibrissae shape
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Stomach
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
7.38×10-06
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Creatine kinase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.479
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail length
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Fat mass
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.237
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Body Composition (DEXA lean/fat) / Fat mass
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.886
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Potassium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.605
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Auditory Brain Stem Response / 30kHz-evoked ABR Threshold
|
HOM
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0381
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Phosphorus
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.648
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair appearance
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Thyroxine
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.694
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Viability Primary Screen / Viability Outcome
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forelimb size
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head bobbing/circling
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Lymphocyte cell count
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.000754
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal skin colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw nail colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Skin
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair colour pattern
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Intraperitoneal glucose tolerance test (IPGTT) / Body Weight
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Center distance travelled
|
HOM
|
10f:12m
|
Linear Mixed Model framework, LME, not including Weight
|
0.223
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Auditory Brain Stem Response / 18kHz-evoked ABR Threshold
|
HOM
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0313
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Triglycerides
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.486
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / B cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head size
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Body Weight / Body weight curve
|
HOM
|
89f:65m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Body Weight / Body weight curve
|
HOM
|
98f:98m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Auditory Brain Stem Response / Body weight
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Hematology / Platelet count
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0573
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Platelet count
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.313
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / External genitalia
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair colour pattern
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindlimb morphology
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Prostate
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
1.85×10-05
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.186
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw nail length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Total protein
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.106
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
3.03×10-05
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.104
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour pattern
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb skin colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Latency to center entry
|
HOM
|
10f:12m
|
Linear Mixed Model framework, LME, not including Weight
|
0.488
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Esophagus
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Incisor colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair colour pattern
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Echo / LVIDd
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.947
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Aspartate aminotransferase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.231
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Auditory Brain Stem Response / Preyer Reflex
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw digit morphology
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Eosinophil cell count
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
1.49×10-14
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head skin appearance
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Large intestine
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Hemoglobin
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.121
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Hematology / Hemoglobin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.916
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw footpad skin appearance
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair appearance
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Total T cell number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Whole arena resting time
|
HOM
|
10f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.138
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Small intestine
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forelimb morphology
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Ovary
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Center average speed
|
HOM
|
10f:12m
|
Linear Mixed Model framework, LME, including Weight
|
8.12×10-05
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Sodium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
2.92×10-05
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Glycerol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0789
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Vibrissae size
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.130
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Trachea
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0699
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0929
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Corneal touch reflex
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Spinal cord
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Neutrophil differential count
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.988
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Contact righting reflex
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal skin appearance
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Vibrissae colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Skeletal muscle
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw nail morphology
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / HDL-cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.317
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw footpad size
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HOM
|
35f:35m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Periphery average speed
|
HOM
|
10f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.000158
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Fertility of Homozygous Knock-out Mice / Gross Findings Male
|
HOM
|
f:m
|
Supplied as data
|
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Fertility of Homozygous Knock-out Mice / Gross Findings Male
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Right Kidney
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Lymphocyte differential count
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.280
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair colour pattern
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Gait (inc. ataxia)
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair appearance
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0863
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral skin appearance
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Monocyte differential count
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.131
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindlimb
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw nail count
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Sample clotted
|
HOM
|
9f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
2.68×10-06
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.942
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Body weight
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Body Composition (DEXA lean/fat) / Body weight
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Distance travelled - total
|
HOM
|
10f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.000382
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Auditory Brain Stem Response / Click-evoked ABR threshold
|
HOM
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0469
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Alpha-amylase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.841
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Urinary bladder
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Iron
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.997
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Auditory Brain Stem Response / 24kHz-evoked ABR Threshold
|
HOM
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0469
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Magnesium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0604
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Convulsions
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Seminal vesicles
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Total cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.121
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Monocyte percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Periphery permanence time
|
HOM
|
10f:12m
|
Linear Mixed Model framework, LME, not including Weight
|
0.686
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Albumin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00179
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00168
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Echo / LVAWd
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.564
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw digit size
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Monocyte number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw digit fusion
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Number of center entries
|
HOM
|
10f:12m
|
Linear Mixed Model framework, LME, not including Weight
|
0.140
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Eye 2 with optic nerve (within skull)
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Lung
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair appearance
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna rotation
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Echo / LVPWs
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.883
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair appearance
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Hematology / Mean cell volume
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Mean cell volume
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.163
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Free fatty acids
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.942
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Center permanence time
|
HOM
|
10f:12m
|
Linear Mixed Model framework, LME, not including Weight
|
0.689
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Auditory Brain Stem Response / 12kHz-evoked ABR Threshold
|
HOM
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0781
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Whole arena permanence
|
HOM
|
10f:12m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Basophil cell count
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Heart
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.000313
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.350
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna position
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Echo / Ejection Fraction
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.770
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Hematology / Red blood cell count
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.343
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Red blood cell count
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.639
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna skin colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw digit count
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Positional passivity
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw nail length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Mammary gland
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair colour pattern
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw footpad skin colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Eye Morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Vibrissae
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Neutrophil cell count
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00195
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Left Kidney
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna touch reflex
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair presence
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.204
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Liver
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Mouth morphology
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Comment
|
HOM
|
2f:m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / NK cell number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dysmorphology comment
|
HOM
|
f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Total T cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.165
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Periphery resting time
|
HOM
|
10f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.328
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair presence
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Incisors
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral skin colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HOM
|
35f:31m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Testes
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw size
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Fructosamine
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
5.32×10-05
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw digit count
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Alkaline phosphatase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.150
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair presence
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / External genitalia size
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Monocyte cell count
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000309
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / NK cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw nail colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Distance travelled
|
HOM
|
40f:48m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Body Composition (DEXA lean/fat) / Bone Area
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0721
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Bone Area
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.719
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Body Weight / Body weight
|
HOM
|
80f:56m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Body Weight / Body weight
|
HOM
|
84f:84m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Hematology / Mean corpuscular hemoglobin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.166
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Mean corpuscular hemoglobin
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.495
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Additional tissues
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Echo / LVIDs
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.913
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair presence
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw size
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0821
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Total bilirubin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.978
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw digit morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Eye 1 with optic nerve (optic nerve parallel to cassette surface)
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail skin colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb grasping
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair presence
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / BMC/Body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
1.77×10-05
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Body Composition (DEXA lean/fat) / BMC/Body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0221
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Lymph node
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair presence
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna morphology
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw digit size
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Basophil differential count
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
9.28×10-14
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair appearance
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw nail count
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Center resting time
|
HOM
|
10f:12m
|
Linear Mixed Model framework, LME, not including Weight
|
0.865
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Glucose
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
9.54×10-05
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Fertility of Homozygous Knock-out Mice / Gross Findings Female
|
HOM
|
f:m
|
Supplied as data
|
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Fertility of Homozygous Knock-out Mice / Gross Findings Female
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Echo / Fractional Shortening
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.823
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna skin appearance
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Spleen
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Hematology / Red blood cell distribution width
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.664
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / Red blood cell distribution width
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.839
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forelimb
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Gall bladder
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Snout size
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Clinical Chemistry / Chloride
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.367
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Insulin Blood Level / Insulin
|
HOM
|
6f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.823
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell number
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.459
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Lean mass
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0695
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Body Composition (DEXA lean/fat) / Lean mass
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0917
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Open Field / Whole arena average speed
|
HOM
|
10f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.000403
|
Successful |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Tissue Embedding and Block Banking / Thyroid
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Usp15tm1b(EUCOMM)Wtsi
|
WTSI
|
Hematology / White blood cell count
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
1.40×10-08
|
Successful |
Usp15em1(IMPC)Marc
|
MARC
|
Hematology / White blood cell count
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
6.14×10-06
|
Successful |