To perform histopathological examination and annotation on the standard list of tissues (see SOPs for IMPC Gross pathology & Tissue Collection) using the tissue orientation laid out in the SOP for IMPC Tissue Embedding & Block Banking.
Histopathological examination and description of tissues.
Minimum number of mutant animals: 2 mutant males + 2 mutant females
Minimum age of animals: 16 weeks
German Mouse Clinic:
Kleiner DE et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 41: 13131321
Score 
Grade 
Definition 
0 
<5% 
No lesion ( detectable) 
1 
5%33% 
Mild 
2 
>33%66% 
Moderate 
3 
>66% 
Severe 
TCP
0  Normal: Tissue considered to be normal, under the conditions of the study and considering the age, sex and strain of the animal. Alterations may be present, which, under other circumstances, would be considered deviations from normal. 
1  Mild: Observation is visible but involves a minor proportion of the tissue and the clinical consequences of the observation are most likely subclinical. 
2  Moderate: Observation is clearly visible and involves a significant proportion of the tissue; it is likely to have some clinical manifestations that are generally expected to be minor. 
3  Marked: Observation is clearly visible involves a major proportion of the tissue; clinical manifestations are likely and may be associated with significant tissue dysfunction or damage. 
4  Severe: Observation is clearly visible and involves a major proportion of the tissue; clinical manifestations are likely and may be associated with significant tissue dysfunction or damage. 
Version  Type  Req. Upload  Req. Analysis  Annotation  Increment  Option  Ontology Options  Derived  Unit  Data Type  

Brain  MPATH diagnostic term IMPC_HIS_001_001  1.1  ontologyParameter  View all Ontology Options  TEXT  
Brain  Free text diagnostic term IMPC_HIS_002_001  1.1  simpleParameter  TEXT  
Brain  MPATH process term IMPC_HIS_003_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Brain  Severity score IMPC_HIS_004_001  1.0  simpleParameter  012345Not applicable  TEXT  
Brain  Descriptor PATO IMPC_HIS_005_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Brain  Description IMPC_HIS_006_001  1.0  simpleParameter  TEXT  
Eye with optic nerve  MPATH diagnostic term IMPC_HIS_007_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Eye with optic nerve  Free text diagnostic term IMPC_HIS_008_001  1.0  simpleParameter  TEXT  
Eye with optic nerve  MPATH process term IMPC_HIS_009_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Eye with optic nerve  Severity score IMPC_HIS_010_001  1.0  simpleParameter  012345Not applicable  TEXT  
Eye with optic nerve  Descriptor PATO IMPC_HIS_011_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Eye with optic nerve  Description IMPC_HIS_012_001  1.0  simpleParameter  TEXT  
Spinal cord  MPATH diagnostic term IMPC_HIS_013_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Spinal cord  Free text diagnostic term IMPC_HIS_014_001  1.0  simpleParameter  TEXT  
Spinal cord  MPATH process term IMPC_HIS_015_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Spinal cord  Severity score IMPC_HIS_016_001  1.0  simpleParameter  012345Not applicable  TEXT  
Spinal cord  Descriptor PATO IMPC_HIS_017_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Spinal cord  Description IMPC_HIS_018_001  1.0  simpleParameter  TEXT  
Thymus  MPATH diagnostic term IMPC_HIS_019_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Thymus  Free text diagnostic term IMPC_HIS_020_001  1.0  simpleParameter  TEXT  
Thymus  MPATH process term IMPC_HIS_021_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:64] dysplasia
[MPATH:66] dilatation
[MPATH:67] displacement and deformity
[MPATH:72] growth acceleration
[MPATH:73] growth arrest
[MPATH:76] heterotopia
[MPATH:77] homoeotic change
[MPATH:86] organ specific developmental defect
[MPATH:107] congestion
[MPATH:119] hemorrhage and nonspecified extravasation
[MPATH:127] atrophy
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:160] metaplasia
[MPATH:181] fibrosis
[MPATH:182] gliosis
[MPATH:184] sclerosis
[MPATH:185] parenchymal regeneration
[MPATH:186] complete parenchymal regeneration
[MPATH:187] incomplete parenchymal regeneration
[MPATH:194] immune mediated disease
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:218] neoplasia
[MPATH:473] developmental cystic dysplasia
[MPATH:591] fatty infiltration
[MPATH:597] cell and tissue damage process
[MPATH:600] branching defect
[MPATH:601] developmental hypertrophy
[MPATH:604] defective growth and differentiation process
[MPATH:607] healing and repair structure
[MPATH:613] pigmentation
[MPATH:624] involution
[MPATH:55] developmental and structural abnormality

TEXT  
Thymus  Severity score IMPC_HIS_022_001  1.0  simpleParameter  012345Not applicable  TEXT  
Thymus  Descriptor PATO IMPC_HIS_023_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Thymus  Description IMPC_HIS_024_001  1.0  simpleParameter  TEXT  
Thyroid  MPATH diagnostic term IMPC_HIS_025_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Thyroid  Free text diagnostic term IMPC_HIS_026_001  1.0  simpleParameter  TEXT  
Thyroid  MPATH process term IMPC_HIS_027_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:86] organ specific developmental defect
[MPATH:119] hemorrhage and nonspecified extravasation
[MPATH:124] infarction
[MPATH:125] thrombosis
[MPATH:126] growth and differentiation defect
[MPATH:127] atrophy
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:160] metaplasia
[MPATH:181] fibrosis
[MPATH:194] immune mediated disease
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:218] neoplasia
[MPATH:554] dystrophy
[MPATH:597] cell and tissue damage process
[MPATH:604] defective growth and differentiation process
[MPATH:607] healing and repair structure

TEXT  
Thyroid  Severity score IMPC_HIS_028_001  1.0  simpleParameter  012345Not applicable  TEXT  
Thyroid  Descriptor PATO IMPC_HIS_029_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Thyroid  Description IMPC_HIS_030_001  1.0  simpleParameter  TEXT  
Heart  MPATH diagnostic term IMPC_HIS_031_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Heart  Free text diagnostic term IMPC_HIS_032_001  1.0  simpleParameter  TEXT  
Heart  MPATH process term IMPC_HIS_033_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Heart  Severity score IMPC_HIS_034_001  1.0  simpleParameter  012345Not applicable  TEXT  
Heart  Descriptor PATO IMPC_HIS_035_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Heart  Description IMPC_HIS_036_001  1.0  simpleParameter  TEXT  
Trachea  MPATH diagnostic term IMPC_HIS_037_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Trachea  Free text diagnostic term IMPC_HIS_038_001  1.0  simpleParameter  TEXT  
Trachea  MPATH process term IMPC_HIS_039_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:33] intracellular and extracellular accumulation
[MPATH:47] intracellular and extracellular depletion
[MPATH:48] decalcification
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:66] dilatation
[MPATH:79] malposition
[MPATH:80] obstruction and stenosis
[MPATH:81] perforation
[MPATH:86] organ specific developmental defect
[MPATH:107] congestion
[MPATH:119] hemorrhage and nonspecified extravasation
[MPATH:126] growth and differentiation defect
[MPATH:127] atrophy
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:160] metaplasia
[MPATH:179] fibrin deposition
[MPATH:180] fibroblast proliferation
[MPATH:181] fibrosis
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:217] ulcerative inflammation
[MPATH:218] neoplasia
[MPATH:474] ectasia
[MPATH:475] ductal ectasia
[MPATH:547] mucous secretions
[MPATH:580] erosion
[MPATH:597] cell and tissue damage process
[MPATH:601] developmental hypertrophy
[MPATH:604] defective growth and differentiation process
[MPATH:607] healing and repair structure

TEXT  
Trachea  Severity score IMPC_HIS_040_001  1.0  simpleParameter  012345Not applicable  TEXT  
Trachea  Descriptor PATO IMPC_HIS_041_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Trachea  Description IMPC_HIS_042_001  1.0  simpleParameter  TEXT  
Esophagus  MPATH diagnostic term IMPC_HIS_043_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Esophagus  Free text diagnostic term IMPC_HIS_044_001  1.0  simpleParameter  TEXT  
Esophagus  MPATH process term IMPC_HIS_045_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:64] dysplasia
[MPATH:66] dilatation
[MPATH:67] displacement and deformity
[MPATH:71] fusion defect
[MPATH:72] growth acceleration
[MPATH:73] growth arrest
[MPATH:80] obstruction and stenosis
[MPATH:81] perforation
[MPATH:86] organ specific developmental defect
[MPATH:107] congestion
[MPATH:119] hemorrhage and nonspecified extravasation
[MPATH:127] atrophy
[MPATH:175] healing and repair
[MPATH:176] connective tissue replacement
[MPATH:177] angiogenesis
[MPATH:179] fibrin deposition
[MPATH:180] fibroblast proliferation
[MPATH:181] fibrosis
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:217] ulcerative inflammation
[MPATH:218] neoplasia
[MPATH:474] ectasia
[MPATH:580] erosion
[MPATH:591] fatty infiltration
[MPATH:597] cell and tissue damage process
[MPATH:604] defective growth and differentiation process
[MPATH:607] healing and repair structure

TEXT  
Esophagus  Severity score IMPC_HIS_046_001  1.0  simpleParameter  012345Not applicable  TEXT  
Esophagus  Descriptor PATO IMPC_HIS_047_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Esophagus  Description IMPC_HIS_048_001  1.0  simpleParameter  TEXT  
Lung  MPATH diagnostic term IMPC_HIS_049_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Lung  Free text diagnostic term IMPC_HIS_050_001  1.0  simpleParameter  TEXT  
Lung  MPATH process term IMPC_HIS_051_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:33] intracellular and extracellular accumulation
[MPATH:40] hyalinosis
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:59] branching morphogenesis defect
[MPATH:64] dysplasia
[MPATH:79] malposition
[MPATH:80] obstruction and stenosis
[MPATH:81] perforation
[MPATH:86] organ specific developmental defect
[MPATH:106] fluid accumulation
[MPATH:107] congestion
[MPATH:119] hemorrhage and nonspecified extravasation
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:160] metaplasia
[MPATH:175] healing and repair
[MPATH:180] fibroblast proliferation
[MPATH:181] fibrosis
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:218] neoplasia
[MPATH:469] symmetry defect
[MPATH:547] mucous secretions
[MPATH:554] dystrophy
[MPATH:555] mineralisation
[MPATH:580] erosion
[MPATH:591] fatty infiltration
[MPATH:597] cell and tissue damage process
[MPATH:600] branching defect
[MPATH:601] developmental hypertrophy
[MPATH:604] defective growth and differentiation process
[MPATH:607] healing and repair structure

TEXT  
Lung  Severity score IMPC_HIS_052_001  1.0  simpleParameter  012345Not applicable  TEXT  
Lung  Descriptor PATO IMPC_HIS_053_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Lung  Description IMPC_HIS_054_001  1.0  simpleParameter  TEXT  
Liver  MPATH diagnostic term IMPC_HIS_055_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Liver  Free text diagnostic term IMPC_HIS_056_001  1.0  simpleParameter  TEXT  
Liver  MPATH process term IMPC_HIS_057_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Liver  Severity score IMPC_HIS_058_001  1.0  simpleParameter  012345Not applicable  TEXT  
Liver  Descriptor PATO IMPC_HIS_059_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Liver  Description IMPC_HIS_060_001  1.0  simpleParameter  TEXT  
Gall bladder  MPATH diagnostic term IMPC_HIS_061_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Gall bladder  Free text diagnostic term IMPC_HIS_062_001  1.0  simpleParameter  TEXT  
Gall bladder  MPATH process term IMPC_HIS_063_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:40] hyalinosis
[MPATH:64] dysplasia
[MPATH:66] dilatation
[MPATH:67] displacement and deformity
[MPATH:80] obstruction and stenosis
[MPATH:81] perforation
[MPATH:86] organ specific developmental defect
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:474] ectasia
[MPATH:475] ductal ectasia
[MPATH:597] cell and tissue damage process
[MPATH:604] defective growth and differentiation process

TEXT  
Gall bladder  Severity score IMPC_HIS_064_001  1.0  simpleParameter  012345Not applicable  TEXT  
Gall bladder  Descriptor PATO IMPC_HIS_065_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Gall bladder  Description IMPC_HIS_066_001  1.0  simpleParameter  TEXT  
Stomach  MPATH diagnostic term IMPC_HIS_067_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Stomach  Free text diagnostic term IMPC_HIS_068_001  1.0  simpleParameter  TEXT  
Stomach  MPATH process term IMPC_HIS_069_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Stomach  Severity score IMPC_HIS_070_001  1.0  simpleParameter  012345Not applicable  TEXT  
Stomach  Descriptor PATO IMPC_HIS_071_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Stomach  Description IMPC_HIS_072_001  1.0  simpleParameter  TEXT  
Small intestine  MPATH diagnostic term IMPC_HIS_073_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Small intestine  Free text diagnostic term IMPC_HIS_074_001  1.0  simpleParameter  TEXT  
Small intestine  MPATH process term IMPC_HIS_075_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Small intestine  Severity score IMPC_HIS_076_001  1.0  simpleParameter  012345Not applicable  TEXT  
Small intestine  Descriptor PATO IMPC_HIS_077_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Small intestine  Description IMPC_HIS_078_001  1.0  simpleParameter  TEXT  
Large intestine  MPATH diagnostic term IMPC_HIS_079_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Large intestine  Free text diagnostic term IMPC_HIS_080_001  1.0  simpleParameter  TEXT  
Large intestine  MPATH process term IMPC_HIS_081_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Large intestine  Severity score IMPC_HIS_082_001  1.0  simpleParameter  012345Not applicable  TEXT  
Large intestine  Descriptor PATO IMPC_HIS_083_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Large intestine  Description IMPC_HIS_084_001  1.0  simpleParameter  TEXT  
Pancreas  MPATH diagnostic term IMPC_HIS_085_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Pancreas  Free text diagnostic term IMPC_HIS_086_001  1.0  simpleParameter  TEXT  
Pancreas  MPATH process term IMPC_HIS_087_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:33] intracellular and extracellular accumulation
[MPATH:47] intracellular and extracellular depletion
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:64] dysplasia
[MPATH:67] displacement and deformity
[MPATH:72] growth acceleration
[MPATH:73] growth arrest
[MPATH:86] organ specific developmental defect
[MPATH:119] hemorrhage and nonspecified extravasation
[MPATH:126] growth and differentiation defect
[MPATH:127] atrophy
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:180] fibroblast proliferation
[MPATH:181] fibrosis
[MPATH:194] immune mediated disease
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:217] ulcerative inflammation
[MPATH:218] neoplasia
[MPATH:554] dystrophy

TEXT  
Pancreas  Severity score IMPC_HIS_088_001  1.0  simpleParameter  012345Not applicable  TEXT  
Pancreas  Descriptor PATO IMPC_HIS_089_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Pancreas  Description IMPC_HIS_090_001  1.0  simpleParameter  TEXT  
Spleen  MPATH diagnostic term IMPC_HIS_091_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Spleen  Free text diagnostic term IMPC_HIS_092_001  1.0  simpleParameter  TEXT  
Spleen  MPATH process term IMPC_HIS_093_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:33] intracellular and extracellular accumulation
[MPATH:47] intracellular and extracellular depletion
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:64] dysplasia
[MPATH:67] displacement and deformity
[MPATH:72] growth acceleration
[MPATH:73] growth arrest
[MPATH:86] organ specific developmental defect
[MPATH:119] hemorrhage and nonspecified extravasation
[MPATH:126] growth and differentiation defect
[MPATH:127] atrophy
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:180] fibroblast proliferation
[MPATH:181] fibrosis
[MPATH:194] immune mediated disease
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:217] ulcerative inflammation
[MPATH:218] neoplasia
[MPATH:554] dystrophy

TEXT  
Spleen  Severity score IMPC_HIS_094_001  1.0  simpleParameter  012345Not applicable  TEXT  
Spleen  Descriptor PATO IMPC_HIS_095_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Spleen  Description IMPC_HIS_096_001  1.0  simpleParameter  TEXT  
Kidney  MPATH diagnostic term IMPC_HIS_097_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Kidney  Free text diagnostic term IMPC_HIS_098_001  1.0  simpleParameter  TEXT  
Kidney  MPATH process term IMPC_HIS_099_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:33] intracellular and extracellular accumulation
[MPATH:47] intracellular and extracellular depletion
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:64] dysplasia
[MPATH:67] displacement and deformity
[MPATH:72] growth acceleration
[MPATH:73] growth arrest
[MPATH:86] organ specific developmental defect
[MPATH:119] hemorrhage and nonspecified extravasation
[MPATH:126] growth and differentiation defect
[MPATH:127] atrophy
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:180] fibroblast proliferation
[MPATH:181] fibrosis
[MPATH:194] immune mediated disease
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:217] ulcerative inflammation
[MPATH:218] neoplasia
[MPATH:554] dystrophy

TEXT  
Kidney  Severity score IMPC_HIS_100_001  1.0  simpleParameter  012345Not applicable  TEXT  
Kidney  Descriptor PATO IMPC_HIS_101_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Kidney  Description IMPC_HIS_102_001  1.0  simpleParameter  TEXT  
Adrenal gland  MPATH diagnostic term IMPC_HIS_103_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Adrenal gland  Free text diagnostic term IMPC_HIS_104_001  1.0  simpleParameter  TEXT  
Adrenal gland  MPATH process term IMPC_HIS_105_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:33] intracellular and extracellular accumulation
[MPATH:47] intracellular and extracellular depletion
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:64] dysplasia
[MPATH:67] displacement and deformity
[MPATH:72] growth acceleration
[MPATH:73] growth arrest
[MPATH:86] organ specific developmental defect
[MPATH:119] hemorrhage and nonspecified extravasation
[MPATH:126] growth and differentiation defect
[MPATH:127] atrophy
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:180] fibroblast proliferation
[MPATH:181] fibrosis
[MPATH:194] immune mediated disease
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:217] ulcerative inflammation
[MPATH:218] neoplasia
[MPATH:554] dystrophy

TEXT  
Adrenal gland  Severity score IMPC_HIS_106_001  1.0  simpleParameter  012345Not applicable  TEXT  
Adrenal gland  Descriptor PATO IMPC_HIS_107_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Adrenal gland  Description IMPC_HIS_108_001  1.0  simpleParameter  TEXT  
Mammary gland  MPATH diagnostic term IMPC_HIS_109_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Mammary gland  Free text diagnostic term IMPC_HIS_110_001  1.0  simpleParameter  TEXT  
Mammary gland  MPATH process term IMPC_HIS_111_001  1.1  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:47] intracellular and extracellular depletion
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:72] growth acceleration
[MPATH:73] growth arrest
[MPATH:86] organ specific developmental defect
[MPATH:87] germ cell defect
[MPATH:107] congestion
[MPATH:119] hemorrhage and nonspecified extravasation
[MPATH:126] growth and differentiation defect
[MPATH:127] atrophy
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:160] metaplasia
[MPATH:179] fibrin deposition
[MPATH:180] fibroblast proliferation
[MPATH:181] fibrosis
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:218] neoplasia
[MPATH:473] developmental cystic dysplasia
[MPATH:474] ectasia
[MPATH:475] ductal ectasia
[MPATH:597] cell and tissue damage process
[MPATH:601] developmental hypertrophy
[MPATH:604] defective growth and differentiation process

TEXT  
Mammary gland  Severity score IMPC_HIS_112_001  1.1  simpleParameter  012345Not applicable  TEXT  
Mammary gland  Descriptor PATO IMPC_HIS_113_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Mammary gland  Description IMPC_HIS_114_001  1.0  simpleParameter  TEXT  
Lymph node  MPATH diagnostic term IMPC_HIS_115_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Lymph node  Free text diagnostic term IMPC_HIS_116_001  1.0  simpleParameter  TEXT  
Lymph node  MPATH process term IMPC_HIS_117_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:25] tissue specific degenerative process
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:86] organ specific developmental defect
[MPATH:107] congestion
[MPATH:126] growth and differentiation defect
[MPATH:127] atrophy
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:160] metaplasia
[MPATH:194] immune mediated disease
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:218] neoplasia
[MPATH:554] dystrophy
[MPATH:597] cell and tissue damage process
[MPATH:600] branching defect
[MPATH:601] developmental hypertrophy
[MPATH:604] defective growth and differentiation process

TEXT  
Lymph node  Severity score IMPC_HIS_118_001  1.0  simpleParameter  012345Not applicable  TEXT  
Lymph node  Descriptor PATO IMPC_HIS_119_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Lymph node  Description IMPC_HIS_120_001  1.0  simpleParameter  TEXT  
Skin  MPATH diagnostic term IMPC_HIS_121_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Skin  Free text diagnostic term IMPC_HIS_122_001  1.0  simpleParameter  TEXT  
Skin  MPATH process term IMPC_HIS_123_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:33] intracellular and extracellular accumulation
[MPATH:47] intracellular and extracellular depletion
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:64] dysplasia
[MPATH:86] organ specific developmental defect
[MPATH:107] congestion
[MPATH:119] hemorrhage and nonspecified extravasation
[MPATH:120] ecchymosis
[MPATH:122] petechia
[MPATH:124] infarction
[MPATH:125] thrombosis
[MPATH:126] growth and differentiation defect
[MPATH:127] atrophy
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:160] metaplasia
[MPATH:175] healing and repair
[MPATH:176] connective tissue replacement
[MPATH:178] extracellular matrix deposition
[MPATH:179] fibrin deposition
[MPATH:180] fibroblast proliferation
[MPATH:181] fibrosis
[MPATH:194] immune mediated disease
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:217] ulcerative inflammation
[MPATH:218] neoplasia
[MPATH:554] dystrophy
[MPATH:597] cell and tissue damage process
[MPATH:600] branching defect
[MPATH:601] developmental hypertrophy
[MPATH:604] defective growth and differentiation process
[MPATH:607] healing and repair structure

TEXT  
Skin  Severity score IMPC_HIS_124_001  1.0  simpleParameter  012345Not applicable  TEXT  
Skin  Descriptor PATO IMPC_HIS_125_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Skin  Description IMPC_HIS_126_001  1.0  simpleParameter  TEXT  
Skeletal muscle  MPATH diagnostic term IMPC_HIS_127_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Skeletal muscle  Free text diagnostic term IMPC_HIS_128_001  1.0  simpleParameter  TEXT  
Skeletal muscle  MPATH process term IMPC_HIS_129_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:33] intracellular and extracellular accumulation
[MPATH:47] intracellular and extracellular depletion
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:59] branching morphogenesis defect
[MPATH:60] communication defect
[MPATH:64] dysplasia
[MPATH:72] growth acceleration
[MPATH:73] growth arrest
[MPATH:82] persistent embryonic structure
[MPATH:86] organ specific developmental defect
[MPATH:107] congestion
[MPATH:119] hemorrhage and nonspecified extravasation
[MPATH:125] thrombosis
[MPATH:126] growth and differentiation defect
[MPATH:127] atrophy
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:160] metaplasia
[MPATH:175] healing and repair
[MPATH:176] connective tissue replacement
[MPATH:179] fibrin deposition
[MPATH:180] fibroblast proliferation
[MPATH:181] fibrosis
[MPATH:194] immune mediated disease
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:218] neoplasia
[MPATH:554] dystrophy
[MPATH:555] mineralisation
[MPATH:580] erosion
[MPATH:591] fatty infiltration
[MPATH:597] cell and tissue damage process
[MPATH:600] branching defect
[MPATH:601] developmental hypertrophy
[MPATH:604] defective growth and differentiation process
[MPATH:607] healing and repair structure

TEXT  
Skeletal muscle  Severity score IMPC_HIS_130_001  1.0  simpleParameter  012345Not applicable  TEXT  
Skeletal muscle  Descriptor PATO IMPC_HIS_131_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Skeletal muscle  Description IMPC_HIS_132_001  1.0  simpleParameter  TEXT  
Urinary bladder  MPATH diagnostic term IMPC_HIS_133_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Urinary bladder  Free text diagnostic term IMPC_HIS_134_001  1.0  simpleParameter  TEXT  
Urinary bladder  MPATH process term IMPC_HIS_135_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:33] intracellular and extracellular accumulation
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:60] communication defect
[MPATH:64] dysplasia
[MPATH:66] dilatation
[MPATH:78] incomplete closure
[MPATH:79] malposition
[MPATH:80] obstruction and stenosis
[MPATH:86] organ specific developmental defect
[MPATH:106] fluid accumulation
[MPATH:107] congestion
[MPATH:119] hemorrhage and nonspecified extravasation
[MPATH:124] infarction
[MPATH:125] thrombosis
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:160] metaplasia
[MPATH:175] healing and repair
[MPATH:176] connective tissue replacement
[MPATH:179] fibrin deposition
[MPATH:180] fibroblast proliferation
[MPATH:181] fibrosis
[MPATH:194] immune mediated disease
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:217] ulcerative inflammation
[MPATH:218] neoplasia
[MPATH:473] developmental cystic dysplasia
[MPATH:474] ectasia
[MPATH:475] ductal ectasia
[MPATH:554] dystrophy
[MPATH:580] erosion
[MPATH:591] fatty infiltration
[MPATH:597] cell and tissue damage process
[MPATH:601] developmental hypertrophy
[MPATH:604] defective growth and differentiation process
[MPATH:607] healing and repair structure

TEXT  
Urinary bladder  Severity score IMPC_HIS_136_001  1.0  simpleParameter  012345Not applicable  TEXT  
Urinary bladder  Descriptor PATO IMPC_HIS_137_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Urinary bladder  Description IMPC_HIS_138_001  1.0  simpleParameter  TEXT  
Testes  MPATH diagnostic term IMPC_HIS_139_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Testes  Free text diagnostic term IMPC_HIS_140_001  1.0  simpleParameter  TEXT  
Testes  MPATH process term IMPC_HIS_141_001  1.1  ontologyParameter  View all Ontology Options  TEXT  
Testes  Severity score IMPC_HIS_142_001  1.1  simpleParameter  012345Not applicable  TEXT  
Testes  Descriptor PATO IMPC_HIS_143_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Testes  Description IMPC_HIS_144_001  1.0  simpleParameter  TEXT  
Epididymis  MPATH diagnostic term IMPC_HIS_145_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Epididymis  Free text diagnostic term IMPC_HIS_146_001  1.0  simpleParameter  TEXT  
Epididymis  MPATH process term IMPC_HIS_147_001  1.1  ontologyParameter  View all Ontology Options  TEXT  
Epididymis  Severity score IMPC_HIS_148_001  1.1  simpleParameter  012345Not applicable  TEXT  
Epididymis  Descriptor PATO IMPC_HIS_149_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Epididymis  Description IMPC_HIS_150_001  1.0  simpleParameter  TEXT  
Prostate  MPATH diagnostic term IMPC_HIS_151_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Prostate  Free text diagnostic term IMPC_HIS_152_001  1.0  simpleParameter  TEXT  
Prostate  MPATH process term IMPC_HIS_153_001  1.1  ontologyParameter  View all Ontology Options  TEXT  
Prostate  Severity score IMPC_HIS_154_001  1.1  simpleParameter  012345Not applicable  TEXT  
Prostate  Descriptor PATO IMPC_HIS_155_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Prostate  Description IMPC_HIS_156_001  1.0  simpleParameter  TEXT  
Seminal vesicle  MPATH diagnostic term IMPC_HIS_157_001  1.1  ontologyParameter  View all Ontology Options  TEXT  
Seminal vesicle  Free text diagnostic term IMPC_HIS_158_001  1.1  simpleParameter  TEXT  
Seminal vesicle  MPATH process term IMPC_HIS_159_001  1.2  ontologyParameter  View all Ontology Options  TEXT  
Seminal vesicle  Severity score IMPC_HIS_160_001  1.2  simpleParameter  012345Not applicable  TEXT  
Seminal vesicle  Descriptor PATO IMPC_HIS_161_001  1.1  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Seminal vesicle  Description IMPC_HIS_162_001  1.1  simpleParameter  TEXT  
Ovary  MPATH diagnostic term IMPC_HIS_163_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Ovary  Free text diagnostic term IMPC_HIS_164_001  1.0  simpleParameter  TEXT  
Ovary  MPATH process term IMPC_HIS_165_001  1.1  ontologyParameter  View all Ontology Options  TEXT  
Ovary  Severity score IMPC_HIS_166_001  1.1  simpleParameter  012345Not applicable  TEXT  
Ovary  Descriptor PATO IMPC_HIS_167_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Ovary  Description IMPC_HIS_168_001  1.0  simpleParameter  TEXT  
Uterus  MPATH diagnostic term IMPC_HIS_169_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Uterus  Free text diagnostic term IMPC_HIS_170_001  1.0  simpleParameter  TEXT  
Uterus  MPATH process term IMPC_HIS_171_001  1.1  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:33] intracellular and extracellular accumulation
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:64] dysplasia
[MPATH:72] growth acceleration
[MPATH:73] growth arrest
[MPATH:76] heterotopia
[MPATH:77] homoeotic change
[MPATH:78] incomplete closure
[MPATH:79] malposition
[MPATH:86] organ specific developmental defect
[MPATH:107] congestion
[MPATH:119] hemorrhage and nonspecified extravasation
[MPATH:124] infarction
[MPATH:125] thrombosis
[MPATH:126] growth and differentiation defect
[MPATH:127] atrophy
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:160] metaplasia
[MPATH:175] healing and repair
[MPATH:176] connective tissue replacement
[MPATH:178] extracellular matrix deposition
[MPATH:179] fibrin deposition
[MPATH:180] fibroblast proliferation
[MPATH:181] fibrosis
[MPATH:194] immune mediated disease
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:218] neoplasia
[MPATH:469] symmetry defect
[MPATH:473] developmental cystic dysplasia
[MPATH:474] ectasia
[MPATH:475] ductal ectasia
[MPATH:554] dystrophy
[MPATH:597] cell and tissue damage process
[MPATH:604] defective growth and differentiation process
[MPATH:607] healing and repair structure

TEXT  
Uterus  Severity score IMPC_HIS_172_001  1.1  simpleParameter  012345Not applicable  TEXT  
Uterus  Descriptor PATO IMPC_HIS_173_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Uterus  Description IMPC_HIS_174_001  1.0  simpleParameter  TEXT  
Images IMPC_HIS_177_001  1.0  seriesMediaParameter  IMAGE  
Brain  Significance score IMPC_HIS_179_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Eye with optic nerve  Significance score IMPC_HIS_180_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Spinal cord  Significance score IMPC_HIS_181_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Thymus  Significance score IMPC_HIS_182_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Thyroid  Significance score IMPC_HIS_183_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Heart  Significance score IMPC_HIS_184_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Trachea  Significance score IMPC_HIS_185_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Esophagus  Significance score IMPC_HIS_186_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Lung  Significance score IMPC_HIS_187_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Liver  Significance score IMPC_HIS_188_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Gall bladder  Significance score IMPC_HIS_189_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Stomach  Significance score IMPC_HIS_190_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Small intestine  Significance score IMPC_HIS_191_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Large intestine  Significance score IMPC_HIS_192_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Pancreas  Significance score IMPC_HIS_193_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Spleen  Significance score IMPC_HIS_194_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Kidney  Significance score IMPC_HIS_195_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Adrenal gland  Significance score IMPC_HIS_196_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Mammary gland  Significance score IMPC_HIS_197_002  2.0  simpleParameter  0 (Not significant)1 (Significant)Not applicable  TEXT  
Lymph node  Significance score IMPC_HIS_198_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Skin  Significance score IMPC_HIS_199_002  2.0  simpleParameter  0 (Not significant)1 (Significant )  TEXT  
Skeletal muscle  Significance score IMPC_HIS_200_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Urinary bladder  Significance score IMPC_HIS_201_002  2.0  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Testes  Significance score IMPC_HIS_202_002  2.0  simpleParameter  0 (Not significant)1 (Significant)Not applicable  TEXT  
Epididymis  Significance score IMPC_HIS_203_002  2.0  simpleParameter  0 (Not significant)1 (Significant)Not applicable  TEXT  
Prostate  Significance score IMPC_HIS_204_002  2.0  simpleParameter  0 (Not significant)1 (Significant)Not applicable  TEXT  
Seminal vesicle  Significance score IMPC_HIS_205_002  2.0  simpleParameter  0 (Not significant)1 (Significant)Not applicable  TEXT  
Ovary  Significance score IMPC_HIS_206_002  2.0  simpleParameter  0 (Not significant)1 (Significant)Not applicable  TEXT  
Uterus  Significance score IMPC_HIS_207_002  2.0  simpleParameter  0 (Not significant)1 (Significant)Not applicable  TEXT  
Salivary gland  MPATH diagnostic term IMPC_HIS_209_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Salivary gland  Free text diagnostic term IMPC_HIS_210_001  1.0  simpleParameter  TEXT  
Salivary gland  MPATH process term IMPC_HIS_211_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:47] intracellular and extracellular depletion
[MPATH:49] demyelination
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:64] dysplasia
[MPATH:66] dilatation
[MPATH:72] growth acceleration
[MPATH:73] growth arrest
[MPATH:76] heterotopia
[MPATH:77] homoeotic change
[MPATH:84] supernumerary structure
[MPATH:86] organ specific developmental defect
[MPATH:107] congestion
[MPATH:108] disseminated intravascular coagulation
[MPATH:126] growth and differentiation defect
[MPATH:127] atrophy
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:160] metaplasia
[MPATH:175] healing and repair
[MPATH:176] connective tissue replacement
[MPATH:178] extracellular matrix deposition
[MPATH:179] fibrin deposition
[MPATH:180] fibroblast proliferation
[MPATH:185] parenchymal regeneration
[MPATH:186] complete parenchymal regeneration
[MPATH:187] incomplete parenchymal regeneration
[MPATH:194] immune mediated disease
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:217] ulcerative inflammation
[MPATH:218] neoplasia
[MPATH:469] symmetry defect
[MPATH:474] ectasia
[MPATH:475] ductal ectasia
[MPATH:547] mucous secretions
[MPATH:554] dystrophy
[MPATH:580] erosion
[MPATH:601] developmental hypertrophy

TEXT  
Salivary gland  Severity score IMPC_HIS_212_001  1.2  simpleParameter  012345Not applicable  TEXT  
Salivary gland  Descriptor PATO IMPC_HIS_213_001  1.1  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Salivary gland  Description IMPC_HIS_214_001  1.0  simpleParameter  TEXT  
Salivary gland  Significance score IMPC_HIS_215_001  1.1  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Sternum  MPATH diagnostic term IMPC_HIS_216_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Sternum  Free text diagnostic term IMPC_HIS_217_001  1.1  simpleParameter  TEXT  
Sternum  MPATH process term IMPC_HIS_218_001  1.1  ontologyParameter  View all Ontology Options  TEXT  
Sternum  Severity score IMPC_HIS_219_001  1.0  simpleParameter  012345Not applicable  TEXT  
Sternum  Descriptor PATO IMPC_HIS_220_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Sternum  Description IMPC_HIS_221_001  1.0  simpleParameter  TEXT  
Sternum  Significance score IMPC_HIS_222_001  1.1  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Femur  MPATH diagnostic term IMPC_HIS_223_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Femur  Free text diagnostic term IMPC_HIS_224_001  1.0  simpleParameter  TEXT  
Femur  MPATH process term IMPC_HIS_225_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Femur  Severity score IMPC_HIS_226_001  1.0  simpleParameter  012345Not applicable  TEXT  
Femur  Descriptor PATO IMPC_HIS_227_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Femur  Description IMPC_HIS_228_001  1.0  simpleParameter  TEXT  
Femur  Significance score IMPC_HIS_229_001  1.1  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Bone marrow  MPATH diagnostic term IMPC_HIS_230_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Bone marrow  Free text diagnostic term IMPC_HIS_231_001  1.0  simpleParameter  TEXT  
Bone marrow  MPATH process term IMPC_HIS_232_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Bone marrow  Severity score IMPC_HIS_233_001  1.0  simpleParameter  012345Not applicable  TEXT  
Bone marrow  Descriptor PATO IMPC_HIS_234_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Bone marrow  Description IMPC_HIS_235_001  1.0  simpleParameter  TEXT  
Bone marrow  Significance score IMPC_HIS_236_001  1.1  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Brown adipose tissue  MPATH diagnostic term IMPC_HIS_237_001  1.1  ontologyParameter  View all Ontology Options  TEXT  
Brown adipose tissue  Free text diagnostic term IMPC_HIS_238_001  1.1  simpleParameter  TEXT  
Brown adipose tissue  MPATH process term IMPC_HIS_239_001  1.1  ontologyParameter  View all Ontology Options  TEXT  
Brown adipose tissue  Severity score IMPC_HIS_240_001  1.1  simpleParameter  012345Not applicable  TEXT  
Brown adipose tissue  Descriptor PATO IMPC_HIS_241_001  1.1  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Brown adipose tissue  Description IMPC_HIS_242_001  1.1  simpleParameter  TEXT  
Brown adipose tissue  Significance score IMPC_HIS_243_001  1.2  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Tibia  MPATH diagnostic term IMPC_HIS_244_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Tibia  Free text diagnostic term IMPC_HIS_245_001  1.0  simpleParameter  TEXT  
Tibia  MPATH process term IMPC_HIS_246_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Tibia  Severity score IMPC_HIS_247_001  1.0  simpleParameter  012345Not significant  TEXT  
Tibia  Descriptor PATO IMPC_HIS_248_001  1.0  ontologyParameter  TEXT  
Tibia  Description IMPC_HIS_249_001  1.0  simpleParameter  TEXT  
Tibia  Significance score IMPC_HIS_250_001  1.1  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Knee joint  MPATH diagnostic term IMPC_HIS_251_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Knee joint  Free text diagnostic term IMPC_HIS_252_001  1.0  simpleParameter  TEXT  
Knee joint  MPATH process term IMPC_HIS_253_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Knee joint  Severity score IMPC_HIS_254_001  1.0  simpleParameter  012345Not applicable  TEXT  
Knee joint  Descriptor PATO IMPC_HIS_255_001  1.0  ontologyParameter  TEXT  
Knee joint  Description IMPC_HIS_256_001  1.0  simpleParameter  TEXT  
Knee joint  Significance score IMPC_HIS_257_001  1.1  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Trigeminal V nerve  MPATH diagnostic term IMPC_HIS_258_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Trigeminal V nerve  Free text diagnostic term IMPC_HIS_259_001  1.0  simpleParameter  TEXT  
Trigeminal V nerve  MPATH process term IMPC_HIS_260_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Trigeminal V nerve  Severity score IMPC_HIS_261_001  1.0  simpleParameter  012345Not applicable  TEXT  
Trigeminal V nerve  Descriptor PATO IMPC_HIS_262_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Trigeminal V nerve  Description IMPC_HIS_263_001  1.0  simpleParameter  TEXT  
Trigeminal V nerve  Significance score IMPC_HIS_264_001  1.1  simpleParameter  0 (Not significant)1 (Significat)  TEXT  
Nasal cavity  MPATH diagnostic term IMPC_HIS_265_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Nasal cavity  Free text diagnostic term IMPC_HIS_266_001  1.0  simpleParameter  TEXT  
Nasal cavity  MPATH process term IMPC_HIS_267_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Nasal cavity  Severity score IMPC_HIS_268_001  1.0  simpleParameter  012345Not applicable  TEXT  
Nasal cavity  Descriptor PATO IMPC_HIS_269_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Nasal cavity  Description IMPC_HIS_270_001  1.0  simpleParameter  TEXT  
Nasal cavity  Significance score IMPC_HIS_271_001  1.1  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Ear  MPATH diagnostic term IMPC_HIS_272_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Ear  Free text diagnostic term IMPC_HIS_273_001  1.0  simpleParameter  TEXT  
Ear  MPATH process term IMPC_HIS_274_001  1.1  ontologyParameter  View all Ontology Options  TEXT  
Ear  Severity score IMPC_HIS_275_001  1.0  simpleParameter  012345Not applicable  TEXT  
Ear  Descriptor PATO IMPC_HIS_276_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Ear  Description IMPC_HIS_277_001  1.0  simpleParameter  TEXT  
Ear  Significance score IMPC_HIS_278_001  1.1  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Tooth  MPATH diagnostic term IMPC_HIS_279_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Tooth  Free text diagnostic term IMPC_HIS_280_001  1.0  simpleParameter  TEXT  
Tooth  MPATH process term IMPC_HIS_281_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:48] decalcification
[MPATH:49] demyelination
[MPATH:50] glycogen depletion
[MPATH:51] hypocalcification
[MPATH:52] lipid depletion
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:64] dysplasia
[MPATH:66] dilatation
[MPATH:67] displacement and deformity
[MPATH:72] growth acceleration
[MPATH:73] growth arrest
[MPATH:76] heterotopia
[MPATH:84] supernumerary structure
[MPATH:85] transdifferentiation
[MPATH:86] organ specific developmental defect
[MPATH:126] growth and differentiation defect
[MPATH:127] atrophy
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:160] metaplasia
[MPATH:180] fibroblast proliferation
[MPATH:181] fibrosis
[MPATH:185] parenchymal regeneration
[MPATH:186] complete parenchymal regeneration
[MPATH:187] incomplete parenchymal regeneration
[MPATH:218] neoplasia
[MPATH:474] ectasia
[MPATH:475] ductal ectasia
[MPATH:555] mineralisation
[MPATH:580] erosion
[MPATH:640] osteoid deposition

TEXT  
Tooth  Severity score IMPC_HIS_282_001  1.0  simpleParameter  012345Not applicable  TEXT  
Tooth  Descriptor PATO IMPC_HIS_283_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Tooth  Description IMPC_HIS_284_001  1.0  simpleParameter  TEXT  
Tooth  Significance score IMPC_HIS_285_001  1.1  simpleParameter  0 (not significant)1 (significant )  TEXT  
Tongue  MPATH diagnostic term IMPC_HIS_286_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Tongue  Free text diagnostic term IMPC_HIS_287_001  1.0  simpleParameter  TEXT  
Tongue  MPATH process term IMPC_HIS_288_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Tongue  Severity score IMPC_HIS_289_001  1.0  simpleParameter  012345Not applicable  TEXT  
Tongue  Descriptor PATO IMPC_HIS_290_001  1.0  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Tongue  Description IMPC_HIS_291_001  1.0  simpleParameter  TEXT  
Tongue  Significance score IMPC_HIS_292_001  1.1  simpleParameter  0 (not significant)1 (significant)  TEXT  
Sciatic nerve  MPATH diagnostic term IMPC_HIS_293_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Sciatic nerve  Free text diagnostic term IMPC_HIS_294_001  1.0  simpleParameter  TEXT  
Sciatic nerve  MPATH process term IMPC_HIS_295_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:33] intracellular and extracellular accumulation
[MPATH:42] lipid deposition
[MPATH:49] demyelination
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:85] transdifferentiation
[MPATH:86] organ specific developmental defect
[MPATH:127] atrophy
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:160] metaplasia
[MPATH:182] gliosis
[MPATH:194] immune mediated disease
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:217] ulcerative inflammation
[MPATH:218] neoplasia
[MPATH:554] dystrophy
[MPATH:597] cell and tissue damage process
[MPATH:600] branching defect
[MPATH:601] developmental hypertrophy
[MPATH:604] defective growth and differentiation process

TEXT  
Sciatic nerve  Severity score IMPC_HIS_296_001  1.0  simpleParameter  012345Not applicable  TEXT  
Sciatic nerve  Descriptor PATO IMPC_HIS_297_001  1.0  ontologyParameter  TEXT  
Sciatic nerve  Description IMPC_HIS_298_001  1.0  simpleParameter  TEXT  
Sciatic nerve  Significance score IMPC_HIS_299_001  1.1  simpleParameter  0 (Not significant)1 (Significant)  TEXT  
Brain IMPC_HIS_300_001  1.1  simpleParameter  TEXT  
Eye with optic nerve IMPC_HIS_301_001  1.1  simpleParameter  TEXT  
Spinal cord IMPC_HIS_302_001  1.1  simpleParameter  TEXT  
Thymus IMPC_HIS_303_001  1.1  simpleParameter  TEXT  
Thyroid IMPC_HIS_304_001  1.1  simpleParameter  TEXT  
Heart IMPC_HIS_305_001  1.1  simpleParameter  TEXT  
Trachea IMPC_HIS_306_001  1.1  simpleParameter  TEXT  
Esophagus IMPC_HIS_307_001  1.1  simpleParameter  TEXT  
Lung IMPC_HIS_308_001  1.1  simpleParameter  TEXT  
Liver IMPC_HIS_309_001  1.1  simpleParameter  TEXT  
Gall bladder IMPC_HIS_310_001  1.0  simpleParameter  TEXT  
Stomach IMPC_HIS_311_001  1.0  simpleParameter  TEXT  
Small intestine IMPC_HIS_312_001  1.0  simpleParameter  TEXT  
Large intestine IMPC_HIS_313_001  1.0  simpleParameter  TEXT  
Pancreas IMPC_HIS_314_001  1.0  simpleParameter  TEXT  
Spleen IMPC_HIS_315_001  1.0  simpleParameter  TEXT  
Kidney IMPC_HIS_316_001  1.0  simpleParameter  TEXT  
Adrenal gland IMPC_HIS_317_001  1.0  simpleParameter  TEXT  
Mammary gland IMPC_HIS_318_001  1.0  simpleParameter  TEXT  
Lymph node IMPC_HIS_319_001  1.0  simpleParameter  TEXT  
Skin IMPC_HIS_320_001  1.0  simpleParameter  TEXT  
Skeletal muscle IMPC_HIS_321_001  1.0  simpleParameter  TEXT  
Urinary bladder IMPC_HIS_322_001  1.0  simpleParameter  TEXT  
Testes IMPC_HIS_323_001  1.0  simpleParameter  TEXT  
Epididymis IMPC_HIS_324_001  1.0  simpleParameter  TEXT  
Prostate IMPC_HIS_325_001  1.0  simpleParameter  TEXT  
Seminal vesicle IMPC_HIS_326_001  1.0  simpleParameter  TEXT  
Ovary IMPC_HIS_327_001  1.0  simpleParameter  TEXT  
Uterus IMPC_HIS_328_001  1.0  simpleParameter  TEXT  
Salivary gland IMPC_HIS_329_001  1.0  simpleParameter  TEXT  
Sternum IMPC_HIS_330_001  1.0  simpleParameter  TEXT  
Femur IMPC_HIS_331_001  1.0  simpleParameter  TEXT  
Bone marrow IMPC_HIS_332_001  1.0  simpleParameter  TEXT  
Brown adipose tissue IMPC_HIS_333_001  1.1  simpleParameter  TEXT  
Tibia IMPC_HIS_334_001  1.0  simpleParameter  TEXT  
Knee joint IMPC_HIS_335_001  1.0  simpleParameter  TEXT  
Trigeminal V nerve IMPC_HIS_336_001  1.0  simpleParameter  TEXT  
Nasal cavity IMPC_HIS_337_001  1.0  simpleParameter  TEXT  
Ear IMPC_HIS_338_001  1.0  simpleParameter  TEXT  
Tooth IMPC_HIS_339_001  1.0  simpleParameter  TEXT  
Tongue IMPC_HIS_340_001  1.0  simpleParameter  TEXT  
Sciatic nerve IMPC_HIS_341_001  1.0  simpleParameter  TEXT  
Bone  MPATH diagnostic term IMPC_HIS_342_001  1.0  ontologyParameter  View all Ontology Options  TEXT  
Bone  Free text diagnostic term IMPC_HIS_343_001  1.0  simpleParameter  TEXT  
Bone  MPATH process term IMPC_HIS_344_001  1.0  ontologyParameter  + Expand [MPATH:458] normal
[MPATH:1] cell and tissue damage
[MPATH:2] cell death
[MPATH:4] necrosis
[MPATH:14] degenerative change
[MPATH:25] tissue specific degenerative process
[MPATH:36] calcium deposition
[MPATH:55] developmental and structural abnormality
[MPATH:57] agenesis
[MPATH:58] aplasia
[MPATH:64] dysplasia
[MPATH:67] displacement and deformity
[MPATH:71] fusion defect
[MPATH:73] growth arrest
[MPATH:78] incomplete closure
[MPATH:86] organ specific developmental defect
[MPATH:126] growth and differentiation defect
[MPATH:127] atrophy
[MPATH:133] hypoplasia
[MPATH:134] hyperplasia
[MPATH:159] hypertrophy
[MPATH:160] metaplasia
[MPATH:175] healing and repair
[MPATH:180] fibroblast proliferation
[MPATH:181] fibrosis
[MPATH:212] inflammation
[MPATH:213] acute inflammation
[MPATH:214] chronic inflammation
[MPATH:215] granulomatous inflammation
[MPATH:216] necrotic inflammation
[MPATH:218] neoplasia
[MPATH:469] symmetry defect
[MPATH:470] left/right axis defect
[MPATH:471] anterior/posterior axis defect
[MPATH:472] dorsal/ventral axis defect
[MPATH:473] developmental cystic dysplasia
[MPATH:601] developmental hypertrophy
[MPATH:604] defective growth and differentiation process
[MPATH:607] healing and repair structure

TEXT  
Bone  Severity score IMPC_HIS_345_001  1.0  simpleParameter  TEXT  
Bone  Descriptor PATO IMPC_HIS_346_001  1.1  ontologyParameter  + Expand [PATO:0000461] normal
[PATO:0000394] mild
[PATO:0000395] moderate
[PATO:0000465] marked
[PATO:0000396] severe
[PATO:0002387] peracute
[PATO:0000389] acute
[PATO:0002091] subacute
[PATO:0001863] chronic
[PATO:0002414] chronicactive
[PATO:0000627] focal
[PATO:0002415] focally extensive
[PATO:0001791] multifocal
[PATO:0002402] multifocal to coalescing
[PATO:0002401] random
[PATO:0001566] diffuse
[PATO:0002403] generalized
[PATO:0000634] unilateral
[PATO:0000618] bilateral
[PATO:0002404] segmental
[PATO:0000632] symmetrical
[PATO:0002417] transmural

TEXT  
Bone  Description IMPC_HIS_347_001  1.0  simpleParameter  TEXT  
Bone  Significance score IMPC_HIS_348_001  1.0  simpleParameter  TEXT  
Bone IMPC_HIS_349_001  1.0  simpleParameter  TEXT 
Version  Type  Req. Upload  Req. Analysis  Annotation  Increment  Option  Ontology Options  Derived  Unit  Data Type  

Stain IMPC_HIS_175_001  1.1  procedureMetadata  H&ECresyl violetLFB  TEXT  
Section thickness IMPC_HIS_176_001  1.1  procedureMetadata  3456  um  TEXT  
Severity maximum score IMPC_HIS_178_001  1.0  procedureMetadata  3 (Centers recording 03 )4 (Centers recording 04)5 (Centers recording 05)  TEXT  
Experimenter ID IMPC_HIS_208_001  1.1  procedureMetadata  TEXT 