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Purpose
Overall indicator marker of animal health (changes in temperature correlate with severity of disease in many murine models).
Experimental Design
- Minimum number of animals : 7M +7F
- Age at test:Week 73
- Sex: We do not expect the results of this test to show sexual dimorphism.
Procedure
- The respective mouse is identified via the ear tag.
- The mouse is isolated and 3 images per mouse are taken (using Infrared thermography (IRT), high resolution A655sc FLIR infrared camera) as soon as the eyes are visible, and their four feet are on the floor.
- The average of the whole body surface temperature and the maximum temperature (at the eyes) are used to evaluate the phenotype.
Notes
passive, remote, and non invasive method