Phenotype: decreased memory-marker CD4-positive NK T cell number

Definition
reduction in the number of memory-marker CD4-positive NK T cells with a CD44+ CD62L- phenotype
Synonyms
reduced memory-marker CD4-positive NK T cell number
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased memory-marker CD4-positive NK T cell number

Total number of significant genotype-phenotype associations: 12

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Arhgef1
Arhgef1tm1a(EUCOMM)Wtsi
HOM   Early adult decreased memory-marker CD4-positive NK T cell number Resting CD4+ NKT cells - % of CD4+ NKT cells
Spleen Immunophenotyping
WTSI
3i
0.00
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM   Early adult decreased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of CD45+
Spleen Immunophenotyping
WTSI
3i
0.00
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM   Early adult decreased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of CD4+ NKT cells
Spleen Immunophenotyping
WTSI
3i
0.00
Gmds
Gmdstm1a(KOMP)Wtsi
HOM   Early adult decreased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of CD45+
Spleen Immunophenotyping
WTSI
3i
0.00
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM   Early adult decreased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of CD45+
Spleen Immunophenotyping
WTSI
3i
0.00
Tmem150b
Tmem150bem1(IMPC)Ccpcz
HOM Early adult decreased memory-marker CD4-positive NK T cell number CD4 CD44+CD62L+ NKT cells
Immunophenotyping
CCP-IMG
IMPC
1.75×10-12
Cd38
Cd38em1(IMPC)Ccpcz
HOM Early adult decreased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of live leukocytes (Panel A)
Immunophenotyping
CCP-IMG
IMPC
1.53×10-10
Ubd
Ubdtm1b(EUCOMM)Wtsi
HOM Early adult decreased memory-marker CD4-positive NK T cell number CD4 CD44+CD62L+ NKT cells
Immunophenotyping
CCP-IMG
IMPC
1.59×10-09
Ppp3cb
Ppp3cbem1(IMPC)Ccpcz
HOM Early adult decreased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of live leukocytes (Panel A)
Immunophenotyping
CCP-IMG
IMPC
4.58×10-06
Prss54
Prss54em1(IMPC)Ccpcz
HOM Early adult decreased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of live leukocytes (Panel A)
Immunophenotyping
CCP-IMG
IMPC
1.45×10-05
Gpr83
Gpr83em1(IMPC)Ccpcz
HOM Early adult decreased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of live leukocytes (Panel A)
Immunophenotyping
CCP-IMG
IMPC
8.20×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

1.35% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased memory-marker CD4-positive NK T cell number (11/812)

1.40% females (5/356) 0.56% males (2/354)

Select a parameter    



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter