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Gene: Ewsr1

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Name
Ewing sarcoma breakpoint region 1
MGI ID
MGI:99960
Synonyms
Ews
Viability
Data available
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (21) Measurements chart (220) All data table (736)
Expression & images (30) Disease models (0) Histopathology (1) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal placenta size Ewsr1tm1b(EUCOMM)Wtsi HET E12.5 0.00
abnormal embryo size Ewsr1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
abnormal forebrain morphology Ewsr1tm1b(EUCOMM)Wtsi HET E12.5 0.00
abnormal craniofacial morphology Ewsr1tm1b(EUCOMM)Wtsi HET E12.5 0.00
abnormal placenta size Ewsr1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
abnormal eye morphology Ewsr1tm1b(EUCOMM)Wtsi HET E12.5 0.00
decreased startle reflex Ewsr1tm1b(EUCOMM)Wtsi HET Early adult 6.14×10-07
abnormal eye morphology Ewsr1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
increased circulating alkaline phosphatase level Ewsr1tm1b(EUCOMM)Wtsi HET Early adult 1.12×10-06
abnormal embryo size Ewsr1tm1b(EUCOMM)Wtsi HOM E15.5 0.00
short tibia Ewsr1tm1b(EUCOMM)Wtsi HET Early adult 3.78×10-07
increased lymphocyte cell number Ewsr1tm1b(EUCOMM)Wtsi HET Early adult 1.22×10-05
abnormal craniofacial morphology Ewsr1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
decreased circulating glucose level Ewsr1tm1b(EUCOMM)Wtsi HET Early adult 4.92×10-06
increased leukocyte cell number Ewsr1tm1b(EUCOMM)Wtsi HET Early adult 6.06×10-06
decreased circulating cholesterol level Ewsr1tm1b(EUCOMM)Wtsi HET   Early adult 9.78×10-06
preweaning lethality, complete penetrance Ewsr1tm1b(EUCOMM)Wtsi HOM   Early adult 0.00
abnormal embryo size Ewsr1tm1b(EUCOMM)Wtsi HET E15.5 0.00
hyperactivity Ewsr1tm1b(EUCOMM)Wtsi HET   Early adult 1.31×10-05
abnormal neural tube closure Ewsr1tm1b(EUCOMM)Wtsi HET E12.5 0.00
abnormal embryo size Ewsr1tm1b(EUCOMM)Wtsi HET E12.5 0.00

Download data as:  TSV  XLS

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/65)  (2/2) N/A
Brain 6  (6/506)  (2/9) N/A
Central nervous system ganglion 2  (1/74)  (2/2) N/A
Ear 6  (1/506)  (2/9) N/A
Embryo 6  (1/507)  (2/9) N/A
Eye 6  (1/506)  (2/9) N/A
Foot 6  (1/506)  (2/9) N/A
Forebrain 6  (1/506)  (2/9) N/A
Forelimb 6  (1/506)  (2/9) N/A
Gut 2  (1/60)  (2/2) N/A
Hand 6  (1/506)  (2/9) N/A
Head 6  (5/506)  (2/9) N/A
Heart 6  (1/506)  (2/9) N/A
Hindbrain 6  (6/506)  (2/9) N/A
Hindlimb 6  (1/506)  (2/9) N/A
Liver 6  (1/504)  (2/9) N/A
Lung 6  (1/504)  (2/9) N/A
Mandibular process 6  (1/506)  (2/9) N/A
Maxillary process 6  (1/506)  (2/9) N/A
Midbrain 6  (1/506)  (2/9) N/A
Nose 2  (1/76)  (2/2) N/A
Oral cavity 6  (1/504)  (2/9) N/A
Chorioallantoic placenta 2  (7/39)  (2/2) N/A
Skeleton 2  (1/76)  (2/2) N/A
Skin 6  (1/506)  (2/9) N/A
Spinal cord 2  (1/73)  (2/2) N/A
Tail 6  (1/506)  (2/9) N/A
Tail somite 6  (1/506)  (2/9) N/A
Trachea 2  (1/60)  (2/2) N/A
Urinary system 2  (1/60)  (2/2) N/A

 Associated Images

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Embryo LacZ: LacZ images wholemount
36 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
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X-ray: XRay Images Skull Lateral Orientation
10 Images
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X-ray: XRay Images Whole Body Dorso Ventral
10 Images
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X-ray: XRay Images Whole Body Lateral Orientation
10 Images
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Gross Pathology and Tissue Collection
8 Images
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Histopathology
1 Images
Immunophenotyping: Panel A FCS file(s)
1 Images
Immunophenotyping: Panel B FCS file(s)
1 Images
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Eye Morphology: Images Ophthalmoscopy
1 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Sternum - developmental and structural abnormality Ewsr1tm1b(EUCOMM)Wtsi HET Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ewsr1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Ewsr1tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Ewsr1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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