Gene: Ewsr1

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Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Ewsr1tm1b(EUCOMM)Wtsi HOM   Early adult 0.00
increased circulating alkaline phosphatase level Ewsr1tm1b(EUCOMM)Wtsi HET Early adult 2.05×10-05
edema Ewsr1tm1b(EUCOMM)Wtsi HET E15.5 0.00
edema Ewsr1tm1b(EUCOMM)Wtsi HOM E15.5 0.00
decreased startle reflex Ewsr1tm1b(EUCOMM)Wtsi HET Early adult 1.23×10-09
increased leukocyte cell number Ewsr1tm1b(EUCOMM)Wtsi HET Early adult 6.35×10-06
decreased circulating cholesterol level Ewsr1tm1b(EUCOMM)Wtsi HET   Early adult 5.85×10-05
short tibia Ewsr1tm1b(EUCOMM)Wtsi HET Early adult 2.80×10-07
decreased circulating glucose level Ewsr1tm1b(EUCOMM)Wtsi HET Early adult 3.77×10-06
hyperactivity Ewsr1tm1b(EUCOMM)Wtsi HET   Early adult 1.31×10-05
increased lymphocyte cell number Ewsr1tm1b(EUCOMM)Wtsi HET Early adult 1.23×10-05

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 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/64)  (2/2) N/A
6  (6/505)  (2/9) N/A
2  (1/73)  (2/2) N/A
6  (1/505)  (2/9) N/A
6  (1/506)  (2/9) N/A
6  (1/505)  (2/9) N/A
6  (1/505)  (2/9) N/A
6  (1/505)  (2/9) N/A
6  (1/505)  (2/9) N/A
2  (1/59)  (2/2) N/A
6  (1/505)  (2/9) N/A
6  (5/505)  (2/9) N/A
6  (1/505)  (2/9) N/A
6  (6/505)  (2/9) N/A
6  (1/505)  (2/9) N/A
6  (1/503)  (2/9) N/A
6  (1/503)  (2/9) N/A
6  (1/505)  (2/9) N/A
6  (1/505)  (2/9) N/A
6  (1/505)  (2/9) N/A
2  (1/75)  (2/2) N/A
6  (1/503)  (2/9) N/A
2  (7/39)  (2/2) N/A
2  (1/75)  (2/2) N/A
6  (1/505)  (2/9) N/A
2  (1/72)  (2/2) N/A
6  (1/505)  (2/9) N/A
6  (1/505)  (2/9) N/A
2  (1/59)  (2/2) N/A
2  (1/59)  (2/2) N/A

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
36 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Histopathology
1 Images
Gross Pathology and Tissue Collection
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Immunophenotyping: Panel A FCS file(s)
1 Images
Eye Morphology: Images Ophthalmoscopy
1 Images
Immunophenotyping: Panel B FCS file(s)
1 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Sternum - developmental and structural abnormality Ewsr1tm1b(EUCOMM)Wtsi HET Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ewsr1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Ewsr1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ewsr1tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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