Gene: Slc1a3

Name
solute carrier family 1 (glial high affinity glutamate transporter), member 3
MGI ID
MGI:99917
Synonyms
Gmt1 B430115D02Rik GLAST MGluT1 Eaat1
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Forelimb digit - size HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Tail - thickness HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Bulging eye HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Forelimb nail - shape HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Electrocardiogram (ECG) / RR HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.165 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Skin texture - whole body HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Trunk curl HET 7f:9m Fisher Exact Test framework 0.0667 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Iris/Pupil HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Plasma Chemistry / Triglycerides HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.848 Success
Slc1a3tm1.1(KOMP)Mbp JAX Hematology / Mean cell hemoglobin concentration HET 0f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.247 Success
Slc1a3tm1.1(KOMP)Mbp JAX Hematology / Mean cell hemoglobin concentration HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_007_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Corneal deposits HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HET 0f:2m 0.0774 Success
Slc1a3tm1.1(KOMP)Mbp JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HET 3f:3m 0.376 Success
Slc1a3tm1.1(KOMP)Mbp JAX Viability E18.5 Secondary Screen / Outcome HOM f:m Supplied as data 0.00 Failed - Insufficient numbers to make a call
Slc1a3tm1.1(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / Body length HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.627 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Vibrissae - presence HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Lower teeth appearance HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Lens Opacity HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Skin texture - back paws HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Forelimbs - shape HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Light-Dark Test / Dark side time spent HET 7f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.555 Success
Slc1a3tm1.1(KOMP)Mbp JAX Sleep Wake / Sleep light phase percent HET 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'JAX_SLW_003_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Retina (combined) HET 8f:8m Not processed Success
Slc1a3tm1.1(KOMP)Mbp JAX Tail Suspension / Latency to immobility HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.539 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Contact righting HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Hematology / Hematocrit HET 0f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.201 Success
Slc1a3tm1.1(KOMP)Mbp JAX Hematology / Hematocrit HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_004_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Skin color - ear HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HET 7f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.337 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - number HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HET 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0527 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Coat - color - abdomen HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Rotarod / Learning slope HET 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.377 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Pupil Dilation HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / Fat mass HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.327 Success
Slc1a3tm1.1(KOMP)Mbp JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.381 Success
Slc1a3tm1.1(KOMP)Mbp JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HET 0f:2m 0.145 Success
Slc1a3tm1.1(KOMP)Mbp JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HET 3f:3m 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Hindpaw - shape HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Tremor HET 7f:9m Fisher Exact Test framework 0.0313 Success
Slc1a3tm1.1(KOMP)Mbp JAX Viability Primary Screen / Outcome HOM 30f:24m Supplied as data Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Genitalia - morphology HET 7f:9m Fisher Exact Test framework 0.0158 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Head morphology HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Electrocardiogram (ECG) / ST HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0306 Success
Slc1a3tm1.1(KOMP)Mbp JAX Sleep Wake / Light sleep bout lengths mean HET 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'JAX_SLW_007_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Electroretinography / Rod b-wave amplitude HET 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Upper teeth appearance HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HET 3f:3m 0.174 Success
Slc1a3tm1.1(KOMP)Mbp JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HET 0f:2m 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Light-Dark Test / Percent time in dark HET 7f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.194 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Corneal vascularization HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Sleep Wake / Activity onset with respect to dark onset median HET 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'JAX_SLW_011_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Retinal Blood Vessels Pattern HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.262 Success
Slc1a3tm1.1(KOMP)Mbp JAX Electrocardiogram (ECG) / PQ HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.108 Success
Slc1a3tm1.1(KOMP)Mbp JAX Sleep Wake / Light sleep bout lengths standard deviation HET 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'JAX_SLW_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Hematology / Platelet count HET 0f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.00852 Success
Slc1a3tm1.1(KOMP)Mbp JAX Hematology / Platelet count HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Activity (body position) HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - size HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Skin texture - snout HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Pupil Position HET 8f:8m Fisher Exact Test framework 0.166 Success
Slc1a3tm1.1(KOMP)Mbp JAX Plasma Chemistry / HDL cholesterol HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0216 Success
Slc1a3tm1.1(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / Fat/Body weight HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.973 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Hindlimbs - position HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Eyelid closure HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Light-Dark Test / Time mobile light side HET 7f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.458 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Forelimbs - size HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Sleep Wake / Breath rate during sleep standard deviation HET 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'JAX_SLW_014_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Tail - morphology HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Iris transilumination HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - length HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Vocalization HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Tail Suspension / Time immobile HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.154 Success
Slc1a3tm1.1(KOMP)Mbp JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HET 7f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00689 Success
Slc1a3tm1.1(KOMP)Mbp JAX Hematology / Hemoglobin HET 0f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.592 Success
Slc1a3tm1.1(KOMP)Mbp JAX Hematology / Hemoglobin HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_003_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Electroretinography / Rod b-wave amplitude-left HET 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Vitreous HET 8f:8m Fisher Exact Test framework 0.0147 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Teeth presence HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Lens HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Electrocardiogram (ECG) / QTc HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00229 Success
Slc1a3tm1.1(KOMP)Mbp JAX Grip Strength / Forelimb grip strength normalised against body weight HET 7f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0780 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Head size HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - back HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Optic Disc HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Narrow eye opening HET 8f:8m Fisher Exact Test framework 0.0491 Success
Slc1a3tm1.1(KOMP)Mbp JAX Sleep Wake / Sleep dark phase percent HET 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'JAX_SLW_004_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Forepaw - shape HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Heart Weight / Heart weight HET 3f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Slc1a3tm1.1(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.660 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Skin color - snout HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Persistence of hyaloid vascular system HET 8f:8m Fisher Exact Test framework 0.190 Success
Slc1a3tm1.1(KOMP)Mbp JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.329 Success
Slc1a3tm1.1(KOMP)Mbp JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.181 Success
Slc1a3tm1.1(KOMP)Mbp JAX Light-Dark Test / Latency to first transition into dark HET 7f:9m Mixed Model framework, linear mixed-effects model, equation withWeight 0.389 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Pupil Shape HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Electrocardiogram (ECG) / QTc Dispersion HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.681 Success
Slc1a3tm1.1(KOMP)Mbp JAX Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Eye HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Sleep Wake / Dark sleep bout lengths standard deviation HET 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'JAX_SLW_010_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Viability E12.5 Secondary Screen / Outcome HOM f:m Supplied as data 0.00 Failed - Insufficient numbers to make a call
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Mouth morphology HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Head bobbing HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Light-Dark Test / Percent time in light HET 7f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.194 Success
Slc1a3tm1.1(KOMP)Mbp JAX Heart Weight / Tibia length HET 3f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Slc1a3tm1.1(KOMP)Mbp JAX Plasma Chemistry / Total cholesterol HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.224 Success
Slc1a3tm1.1(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / Lean/Body weight HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.985 Success
Slc1a3tm1.1(KOMP)Mbp JAX Electrocardiogram (ECG) / rMSSD HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0343 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Skin texture - ear HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Snout size HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Electrocardiogram (ECG) / PR HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0269 Success
Slc1a3tm1.1(KOMP)Mbp JAX Sleep Wake / Dark sleep bout lengths mean HET 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'JAX_SLW_009_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Synechia HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HET 0f:2m 0.0636 Success
Slc1a3tm1.1(KOMP)Mbp JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HET 3f:3m 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Light-Dark Test / Light side time spent HET 7f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.555 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Genitalia - size HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Forelimb nail - length HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HET 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.124 Success
Slc1a3tm1.1(KOMP)Mbp JAX Electrocardiogram (ECG) / HR HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.129 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Aggression HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Electroretinography / Rod b-wave amplitude-right HET 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Hindlimbs - shape HET 7f:9m Fisher Exact Test framework 0.00529 Success
Slc1a3tm1.1(KOMP)Mbp JAX Grip Strength / Forelimb grip strength measurement mean HET 7f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.731 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Startle response HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Eyelid morphology HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Hematology / Mean cell volume HET 0f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0246 Success
Slc1a3tm1.1(KOMP)Mbp JAX Hematology / Mean cell volume HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_005_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Coat - color - back HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Sleep Wake / Sleep daily percent HET 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'JAX_SLW_002_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Forelimb digit - shape HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Cornea HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HET 0f:2m 0.0774 Success
Slc1a3tm1.1(KOMP)Mbp JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HET 3f:3m 0.229 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Hindpaw - size HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0789 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Upper lip morphology HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Locomotor activity HET 7f:9m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0136 Success
Slc1a3tm1.1(KOMP)Mbp JAX Hematology / Red blood cell count HET 0f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.223 Success
Slc1a3tm1.1(KOMP)Mbp JAX Hematology / Red blood cell count HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_002_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Skin texture - tail HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Vibrissae - appearance HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Iris Pigmentation HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Electrocardiogram (ECG) / HRV HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.465 Success
Slc1a3tm1.1(KOMP)Mbp JAX Sleep Wake / Breath rate during sleep mean HET 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'JAX_SLW_013_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.313 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Retinal Blood Vessels HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Sleep Wake / Sleep bout lengths mean HET 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'JAX_SLW_005_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Skin color - back paws HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Electroretinography / Rod a-wave amplitude-right HET 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Limb grasp HET 7f:9m Fisher Exact Test framework 0.0590 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Skin color - whole body HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Rotarod / Average duration HET 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.127 Success
Slc1a3tm1.1(KOMP)Mbp JAX Plasma Chemistry / Glucose HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0171 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - head HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Genitalia - presence HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Light-Dark Test / Side changes HET 7f:9m Mixed Model framework, linear mixed-effects model, equation withWeight 0.639 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - number HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Corneal Sclerization HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Electroretinography / Cone b-wave amplitude HET 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Tail - length HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Eye Hemorrhage or Blood Presence HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Unexpected behaviors HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Hindlimbs - size HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Skin texture - front paws HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / Bone Area HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.555 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Fusion between cornea and lens HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Coat - color - head HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Hematology / Mean corpuscular hemoglobin HET 0f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0827 Success
Slc1a3tm1.1(KOMP)Mbp JAX Hematology / Mean corpuscular hemoglobin HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_006_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Electroretinography / Rod b-wave implicit time HET 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HET 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.428 Success
Slc1a3tm1.1(KOMP)Mbp JAX Electrocardiogram (ECG) / CV HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.449 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Forelimbs - position HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Forepaw - size HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Electroretinography / Cone b-wave amplitude-left HET 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Slc1a3tm1.1(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / BMC/Body weight HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0603 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Lower lip morphology HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Skin color - front paws HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Electroretinography / Cone b-wave amplitude-right HET 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Sleep Wake / Peak wake with respect to dark onset median HET 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'JAX_SLW_012_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Light-Dark Test / Time mobile dark side HET 7f:9m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0491 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Retinal Blood Vessels Structure HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Slc1a3tm1.1(KOMP)Mbp JAX Tail Suspension / Climbing HET 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Forelimb nail - number HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Electroretinography / Rod a-wave implicit time HET 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Gait HET 7f:9m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Electrocardiogram (ECG) / QRS HET 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00545 Success
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Ears HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Electroretinography / Rod a-wave amplitude HET 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Tail - presence HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Plasma Chemistry / Free fatty acids HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0200 Success
Slc1a3tm1.1(KOMP)Mbp JAX Rotarod / Learning difference HET 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.203 Success
Slc1a3tm1.1(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / Lean mass HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.855 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Pupil Light Response HET 8f:8m Fisher Exact Test framework 1.00 Success
Slc1a3tm1.1(KOMP)Mbp JAX Eye Morphology / Corneal opacity HET 8f:8m Fisher Exact Test framework 0.317 Success
Slc1a3tm1.1(KOMP)Mbp JAX Sleep Wake / Sleep bout lengths standard deviation HET 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'JAX_SLW_006_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Forelimb digit - number HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Slc1a3tm1.1(KOMP)Mbp JAX Electroretinography / Rod a-wave amplitude-left HET 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Slc1a3tm1.1(KOMP)Mbp JAX Hematology / White blood cell count HET 0f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.434 Success
Slc1a3tm1.1(KOMP)Mbp JAX Hematology / White blood cell count HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_001_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Slc1a3tm1.1(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Skin color - tail HET 7f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2) N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No  (2/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2) N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2) N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (2/3) N/A
Dorsal root ganglion 2  (1/47) Image Only N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/3)  Wholemount images
Eye 2  (1/485) N/A
Foot 2  (1/485)  (1/3) N/A
Forebrain 2  (1/485)  (2/3) N/A
Forelimb 2  (1/485)  (2/3) N/A
Fronto-nasal process 2  (1/48) Image Only N/A
Hand 2  (1/485)  (1/3) N/A
Head 2  (5/485)  (2/3) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485)  (2/3) N/A
Hindlimb 2  (1/485)  (2/3) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) Image Only N/A
Mandibular process 2  (1/485)  (1/3) N/A
Maxillary process 2  (1/485)  (2/3) N/A
Midbrain 2  (1/485)  (2/3) N/A
Nose 2  (1/51)  (1/3) N/A
Oral cavity 2  (1/485) Image Only N/A
Skin 2  (1/485)  (1/3) N/A
Spinal cord 2  (1/50)  (2/3) N/A
Tail 2  (1/485)  (1/3) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
16 Images
X-ray: XRay Images Forepaw
16 Images
Sleep Wake: Wake state (bmp file)
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
X-ray: XRay Images Dorso Ventral
16 Images
Embryo LacZ: LacZ images wholemount
12 Images
X-ray: XRay Images Skull Lateral Orientation
16 Images
Electroretinography: Cone waveform (pdf format)
3 Images
Electroretinography: Rod waveform (pdf format)
3 Images

 Disease Models

Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Slc1a3tm1(KOMP)Mbp Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Slc1a3tm1.1(KOMP)Mbp Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Slc1a3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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