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Gene: Ppm1a

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Name
protein phosphatase 1A, magnesium dependent, alpha isoform
MGI ID
MGI:99878
Synonyms
Mpp alpha MPPa-1 MMPa-2 2900017D14Rik 2310003C21Rik
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (7) Measurements chart (197) All data table (389)
Expression & images (67) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased erythrocyte cell number Ppm1atm1b(EUCOMM)Hmgu HOM Early adult 9.31×10-06
limb grasping Ppm1atm1b(EUCOMM)Hmgu HOM Early adult 3.76×10-05
decreased startle reflex Ppm1atm1b(EUCOMM)Hmgu HOM   Early adult 1.91×10-05
decreased eosinophil cell number Ppm1atm1b(EUCOMM)Hmgu HOM   Early adult 8.16×10-05
decreased fasting circulating glucose level Ppm1atm1b(EUCOMM)Hmgu HOM   Early adult 4.64×10-06
abnormal bone structure Ppm1atm1b(EUCOMM)Hmgu HOM Early adult 1.81×10-05
increased grip strength Ppm1atm1b(EUCOMM)Hmgu HOM Early adult 2.15×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No  (3/590)  (1/1) N/A
Aorta 1 No  (1/590)  (1/1) N/A
Bone 1 No  (1/1) N/A
Brain 1 No  (3/590)  (1/1) N/A
Brainstem 1 No  (2/590)  (1/1) N/A
Brown adipose tissue 1 No  (1/1) N/A
Cartilage tissue 1 No  (1/1) N/A
Cerebellum 1 No  (3/590)  (1/1) N/A
Cerebral cortex 1 No  (2/590)  (1/1) N/A
Esophagus 1 No  (7/415)  (1/1) N/A
Eye 1 No  (1/1) N/A
Gall bladder 1 No  (1/1) N/A
Heart 1 No  (1/590)  (1/1) N/A
Hippocampus 1 No  (3/590)  (1/1) N/A
Hypothalamus 1 No  (2/590)  (1/1) N/A
Kidney 1 No  (20/590)  (1/1) N/A
Large intestine 1 No  (10/590)  (1/1) N/A
Liver 1 No N/A
Lower urinary tract 1 No  (1/590)  (1/1)  Wholemount images
Lung 1 No  (1/590)  (1/1) N/A
Lymph node 1 No  (1/1) N/A
Mammary gland 1 No N/A
Olfactory lobe 1 No  (2/590)  (1/1) N/A
Oral epithelium 1 No  (1/1) N/A
Ovary 1 No  (1/590) N/A
Oviduct 1 No N/A
Pancreas 1 No  (5/590)  (1/1) N/A
Parathyroid gland 1 No  (1/1) N/A
Peripheral nervous system 1 No  (1/590)  (1/1) N/A
Peyer's patch 1 No  (1/1)  Wholemount images
Pituitary gland 1 No  (1/590)  (1/1) N/A
Prostate gland 1 No  (12/590)  (1/1)  Wholemount images
Skeletal muscle 1 No  (1/1) N/A
Skin 1 No  (1/1) N/A
Small intestine 1 No  (9/590)  (1/1)  Wholemount images
Spinal cord 1 No  (2/590)  (1/1) N/A
Spleen 1 No  (2/590) N/A
Stomach 1 No  (13/590)  (1/1) N/A
Striatum 1 No  (3/590)  (1/1) N/A
Testis 1 No  (5/590)  (1/1)  Wholemount images
Thymus 1 No  (1/1) N/A
Thyroid gland 1 No  (16/590)  (1/1) N/A
Trachea 1 No  (2/590)  (1/1) N/A
Uterus 1 No N/A
Vascular system 1 No  (1/1) N/A
White adipose tissue 1 No  (1/1)  Wholemount images
LacZ Wholemount Images
adipose tissue (1)
Testis expression
White Adipose Tissue expression
MA:0000058
MA:0000411
digestive system (1)
Small Intestine expression
Peyers Patch expression
MA:0000137
MA:0000337
exocrine system (1)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
immune system (1)
Small Intestine expression
Peyers Patch expression
MA:0000137
MA:0000337
postnatal mouse (3)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
reproductive system (2)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
set of connective tissues (1)
Testis expression
White Adipose Tissue expression
MA:0000058
MA:0000411
trunk (3)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
urinary system (1)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (4/4) N/A
Ear 2  (1/506)  (2/4) N/A
Embryo 2  (1/507)  (4/4) N/A
Eye 2  (1/506)  (4/4) N/A
Foot 2  (1/506)  (4/4) N/A
Forebrain 2  (1/506)  (4/4) N/A
Forelimb 2  (1/506)  (4/4) N/A
Hand 2  (1/506)  (4/4) N/A
Head 2  (5/506)  (4/4) N/A
Heart 2  (1/506)  (2/4) N/A
Hindbrain 2  (6/506)  (4/4) N/A
Hindlimb 2  (1/506)  (4/4) N/A
Liver 2  (1/504)  (1/4) N/A
Lung 2  (1/504)  (2/4) N/A
Mandibular process 2  (1/506)  (2/4) N/A
Maxillary process 2  (1/506)  (2/4) N/A
Midbrain 2  (1/506)  (4/4) N/A
Oral cavity 2  (1/504)  (2/4) N/A
Skin 2  (1/506) N/A
Tail 2  (1/506)  (4/4) N/A
Tail somite 2  (1/506)  (2/4) N/A

 Associated Images

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X-ray: XRay Images Whole Body Lateral Orientation
10 Images
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Embryo LacZ: LacZ images wholemount
8 Images
thumbnail
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
thumbnail
Adult LacZ: LacZ Images Wholemount
3 Images
thumbnail
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Immunophenotyping: Panel B FCS file(s)
6 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Immunophenotyping: Panel A FCS file(s)
6 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ppm1atm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Ppm1atm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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