Genes Phenotypes

Gene: Chrna7

Log in to follow

Name
cholinergic receptor, nicotinic, alpha polypeptide 7
MGI ID
MGI:99779
Synonyms
alpha7-nAChR alpha7 Acra7 alpha7 nicotinic receptor
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (3) Measurements chart (231) All data table (419)
Expression & images (67) Disease models (0) Order (4)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal bone structure Chrna7tm1b(EUCOMM)Hmgu HOM Early adult 2.59×10-05
increased circulating HDL cholesterol level Chrna7tm1b(EUCOMM)Hmgu HOM Early adult 1.63×10-05
increased circulating cholesterol level Chrna7tm1b(EUCOMM)Hmgu HOM Early adult 5.11×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
digestive system (3)
Large Intestine expression
MA:0000333
endocrine system (1)
Adrenal gland expression
MA:0000116
nervous system (4)
Cerebral Cortex expression
Striatum expression
Hippocampus expression
Brain expression
MA:0000185
MA:0000891
MA:0000191
MA:0000168
postnatal mouse (10)
Adrenal gland expression
MA:0000116
reproductive system (1)
Testis expression
MA:0000411
trunk (7)
Adrenal gland expression
MA:0000116
urinary system (1)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/504)  (2/2) N/A
Ear 1  (1/504) N/A
Embryo 1  (1/505)  (2/2) N/A
Eye 1  (1/504)  (1/2) N/A
Foot 1  (1/504)  (2/2) N/A
Forebrain 1  (1/504)  (1/2) N/A
Forelimb 1  (1/504)  (1/2) N/A
Hand 1  (1/503)  (2/2) N/A
Head 1  (5/504)  (2/2) N/A
Heart 1  (1/504) N/A
Hindbrain 1  (6/504)  (1/2) N/A
Hindlimb 1  (1/503)  (1/2) N/A
Liver 1  (1/504) N/A
Lung 1  (1/500) N/A
Mandibular process 1  (1/504) N/A
Maxillary process 1  (1/504) N/A
Midbrain 1  (1/504)  (2/2) N/A
Oral cavity 1  (1/504) N/A
Skin 1  (1/504) N/A
Tail 1  (1/504)  (2/2) N/A
Tail somite 1  (1/504) N/A

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Adult LacZ: LacZ Images Wholemount
10 Images
Echo: M-Mode Images
32 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Embryo LacZ: LacZ images wholemount
8 Images

 Disease Models

Please visit the desktop version to see this section

 Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Chrna7tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Chrna7tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Chrna7tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Chrna7tm3a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter