Gene: Chrna7

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Name
cholinergic receptor, nicotinic, alpha polypeptide 7
MGI ID
MGI:99779
Synonyms
Acra7 alpha7 alpha7 nicotinic receptor alpha7-nAChR
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating cholesterol level Chrna7tm1b(EUCOMM)Hmgu HOM Early adult 6.11×10-05
abnormal bone structure Chrna7tm1b(EUCOMM)Hmgu HOM   Early adult 1.99×10-05
increased circulating HDL cholesterol level Chrna7tm1b(EUCOMM)Hmgu HOM Early adult 3.70×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583)  (2/2)  Wholemount images
2 No  (1/583) N/A
2 No N/A
2 No  (4/583)  (2/2)  Wholemount images
2 No  (2/583)  (2/2)  Wholemount images
2 No N/A
2 No  (1/583) N/A
2 No  (3/583) N/A
2 No  (2/583)  (2/2)  Wholemount images
2 No  (7/407) N/A
2 No N/A
2 No N/A
2 No  (2/583) N/A
2 No  (3/583)  (2/2)  Wholemount images
2 No  (2/583)  (2/2)  Wholemount images
2 No  (21/583)  (2/2)  Wholemount images
2 No  (10/583)  (2/2)  Wholemount images
2 No N/A
2 No  (1/583) N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No  (2/583)  (2/2)  Wholemount images
2 No N/A
2 No  (1/583) N/A
2 No N/A
2 No  (5/583) N/A
2 No  (1/563) N/A
2 No  (2/583)  (2/2)  Wholemount images
2 No N/A
2 No  (1/583) N/A
2 No  (12/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (9/583)  (2/2)  Wholemount images
2 No  (3/583)  (2/2)  Wholemount images
2 No  (3/583) N/A
2 No  (13/583)  (2/2)  Wholemount images
2 No  (3/583)  (2/2)  Wholemount images
2 No  (6/583)  (1/2)  Wholemount images
2 No  (1/583) N/A
2 No  (17/583) N/A
2 No  (3/583) N/A
2 No N/A
2 No N/A
2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Echo: M-Mode Images
32 Images
Adult LacZ: LacZ Images Wholemount
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Immunophenotyping: Panel A FCS file(s)
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Immunophenotyping: Panel B FCS file(s)
8 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Chrna7tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Chrna7tm3a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Chrna7tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Chrna7tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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