Gene: Ryr2

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Ryr2tm1b(KOMP)Wtsi HOM Early adult 0.00
increased startle reflex Ryr2tm1b(KOMP)Wtsi HET Early adult 9.81×10-05
decreased circulating glucose level Ryr2tm1b(KOMP)Wtsi HET Early adult 3.01×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (3/590)  (2/2)  Wholemount images
2 No  (1/590)  (2/2)  Wholemount images
2 No N/A
2 No  (3/590)  (2/2)  Wholemount images
2 No  (2/590)  (2/2)  Wholemount images
2 No N/A
2 No N/A
2 No  (3/590)  (2/2)  Wholemount images
2 No  (2/590)  (2/2)  Wholemount images
2 No  (7/415)  (2/2)  Wholemount images
2 No N/A
2 No N/A
2 No  (1/590)  (2/2)  Wholemount images
2 No  (3/590)  (2/2)  Wholemount images
2 No  (2/590)  (2/2)  Wholemount images
2 No  (20/590)  (1/2)  Wholemount images
2 No  (10/590)  (2/2)  Wholemount images
2 No N/A
2 No  (1/590)  (2/2)  Wholemount images
2 No  (1/590)  (2/2)  Wholemount images
2 No  (1/2)  Wholemount images
2 No N/A
2 No  (2/590)  (2/2)  Wholemount images
2 No N/A
2 No  (1/590) N/A
2 No N/A
2 No  (5/590) N/A
2 No N/A
2 No  (1/590)  (2/2)  Wholemount images
2 No N/A
2 No  (1/590)  (2/2)  Wholemount images
2 No  (12/590) N/A
2 No N/A
2 No N/A
2 No  (9/590)  (2/2)  Wholemount images
2 No  (2/590)  (2/2)  Wholemount images
2 No  (2/590) N/A
2 No  (13/590)  (2/2)  Wholemount images
2 No  (3/590)  (2/2)  Wholemount images
2 No  (5/590)  (1/2)  Wholemount images
2 No N/A
2 No  (16/590) N/A
2 No  (2/590)  (2/2)  Wholemount images
2 No N/A
2 No  (2/2)  Wholemount images
2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/506) N/A
2  (1/506) N/A
2  (1/507)  (2/2) N/A
2  (1/506) N/A
2  (1/506) N/A
2  (1/506) N/A
2  (1/506) N/A
2  (1/506) N/A
2  (5/506)  (2/2) N/A
2  (1/506)  (1/2) N/A
2  (6/506) N/A
2  (1/506) N/A
2  (1/504) N/A
2  (1/504)  (1/2) N/A
2  (1/506) N/A
2  (1/506) N/A
2  (1/506) N/A
2  (1/504) N/A
2  (1/506) N/A
2  (1/506)  (1/2) N/A
2  (1/506) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
17 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
Echo: M-Mode Images
28 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Embryo LacZ: LacZ images wholemount
4 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images

 Disease Models

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MGI Allele Allele Type Produced
Ryr2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Ryr2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells