Gene: Abca1

Log in to follow

Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal locomotor behavior Abca1tm1b(EUCOMM)Hmgu HET Early adult 5.28×10-05
preweaning lethality, complete penetrance Abca1tm1b(EUCOMM)Hmgu HOM Early adult 0.00
abnormal embryo size Abca1tm1b(EUCOMM)Hmgu HOM E18.5 0.00
abnormal embryo size Abca1tm1b(EUCOMM)Hmgu HET E18.5 0.00
abnormal retina morphology Abca1tm1b(EUCOMM)Hmgu HET Early adult 2.50×10-06

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 3 No  (3/589)  (2/3)  Wholemount images
Aorta 3 No  (1/589)  (3/3)  Wholemount images
Bone 3 No  (3/3)  Wholemount images
Brain 3 No  (3/589)  (3/3)  Wholemount images
Brainstem 3 No  (2/589)  (3/3)  Wholemount images
Brown adipose tissue 3 No  (3/3)  Wholemount images
Cartilage tissue 3 No  (3/3)  Wholemount images
Cecum 3 No  (12/379) N/A
Cerebellum 3 No  (3/589)  (3/3)  Wholemount images
Cerebral cortex 3 No  (2/589)  (3/3)  Wholemount images
Esophagus 3 No  (7/415) N/A
Eye 3 No N/A
Gall bladder 3 No  (3/3)  Wholemount images
Heart 3 No  (1/589)  (3/3)  Wholemount images
Hippocampus 3 No  (3/589)  (3/3)  Wholemount images
Hypothalamus 3 No  (2/589)  (3/3)  Wholemount images
Kidney 3 No  (20/589)  (3/3)  Wholemount images
Large intestine 3 No  (10/589) N/A
Liver 3 No  (3/3)  Wholemount images
Lower urinary tract 3 No  (1/589)  (3/3)  Wholemount images
Lung 3 No  (1/589)  (3/3) N/A
Lymph node 3 No  (3/3) N/A
Mammary gland 3 No N/A
Olfactory lobe 3 No  (2/589)  (3/3)  Wholemount images
Oral epithelium 3 No  (3/3)  Wholemount images
Ovary 3 No  (1/589)  (1/3)  Wholemount images
Oviduct 3 No  (1/3)  Wholemount images
Pancreas 3 No  (5/589)  (3/3)  Wholemount images
Parathyroid gland 3 No N/A
Peripheral nervous system 3 No  (1/589)  (3/3)  Wholemount images
Peyer's patch 3 No N/A
Pituitary gland 3 No  (1/589)  (3/3)  Wholemount images
Prostate gland 3 No  (12/589)  (2/3)  Wholemount images
Skeletal muscle 3 No  (3/3)  Wholemount images
Skin 3 No  (3/3)  Wholemount images
Small intestine 3 No  (9/589) N/A
Spinal cord 3 No  (2/589)  (3/3)  Wholemount images
Spleen 3 No  (2/589) N/A
Stomach 3 No  (13/589)  (3/3)  Wholemount images
Striatum 3 No  (3/589)  (3/3)  Wholemount images
Testis 3 No  (5/589)  (2/3)  Wholemount images
Thymus 3 No N/A
Thyroid gland 3 No  (16/589)  (3/3)  Wholemount images
Trachea 3 No  (2/589)  (3/3)  Wholemount images
Trigeminal V nerve 3 No  (3/3)  Wholemount images
Uterus 3 No  (1/3)  Wholemount images
Vas deferens 3 No  (15/388)  (1/3)  Wholemount images
Vascular system 3 No N/A
White adipose tissue 3 No  (3/3)  Wholemount images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/61) N/A
Axial skeleton 2  (1/65) N/A
Brain 2  (6/506)  (2/3) N/A
Central nervous system ganglion 2  (1/74)  (1/3) N/A
Cranium 2  (1/65) N/A
Dorsal root ganglion 2  (1/61) N/A
Ear 2  (1/506) N/A
Embryo 2  (1/507)  (2/3) N/A
Outer ear 2  (1/70) N/A
Eye 2  (1/506) N/A
Femur pre-cartilage condensation 2  (1/56)  (2/3) N/A
Foot 2  (1/506)  (2/3) N/A
Forearm 2  (1/301) N/A
Forebrain 2  (1/506)  (2/3) N/A
Forelimb 2  (1/506)  (2/3) N/A
Fronto-nasal process 2  (1/62)  (2/3) N/A
Gut 2  (1/60) N/A
Hand 2  (1/505)  (2/3) N/A
Head 2  (5/506)  (2/3) N/A
Head mesenchyme 2  (1/61)  (2/3) N/A
Heart 2  (1/506) N/A
Heart ventricle 2  (1/61) N/A
Hindbrain 2  (6/506)  (2/3) N/A
Hindlimb 2  (1/505)  (2/3) N/A
Humerus pre-cartilage condensation 2  (1/65) N/A
Inner ear 2  (1/65) N/A
Intestine 2  (1/59) N/A
Liver 2  (1/506)  (2/3) N/A
Lower leg 2  (1/301) N/A
Lung 2  (1/502) N/A
Mandibular process 2  (1/506)  (1/3) N/A
Maxillary process 2  (1/506) N/A
Mesonephros of female 2  (1/56) N/A
Mesonephros of male 2  (1/56) N/A
Metanephros 2  (1/56) N/A
Midbrain 2  (1/506)  (2/3) N/A
Nasal septum 2  (1/61) N/A
Nose 2  (1/74) N/A
Notochord 2  (1/61) N/A
Oral cavity 2  (1/506)  (2/3) N/A
Outflow tract 2  (1/61) N/A
Pancreas 2  (1/56) N/A
Pericardium 2  (1/56)  (2/3) N/A
Pharynx 2  (1/56) N/A
Radius-ulna pre-cartilage condensation 2  (1/65)  (2/3) N/A
Rib pre-cartilage condensation 2  (1/58)  (2/3) N/A
Skeleton 2  (1/74) N/A
Skin 2  (1/506) N/A
Spinal cord 2  (1/73)  (2/3) N/A
Stomach 2  (1/56)  (2/3) N/A
Tail 2  (1/506)  (2/3) N/A
Tail somite 2  (1/506)  (2/3) N/A
Thoracic vertebral cartilage condensation 2  (1/56)  (2/3) N/A
Tongue 2  (1/56)  (2/3) N/A
Trachea 2  (1/60) N/A
Trunk mesenchyme 2  (1/61)  (2/3) N/A
Umbilical artery embryonic part 2  (1/61) N/A
Umbilical vein embryonic part 2  (1/61) N/A
Upper arm 2  (1/301) N/A
Upper leg 2  (1/301) N/A
Urinary system 2  (1/60) N/A
Vibrissa 2  (1/70) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
77 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
X-ray: XRay Images Forepaw
9 Images
Embryo LacZ: LacZ images wholemount
12 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
Immunophenotyping: Panel B FCS file(s)
6 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
MicroCT E18.5: Embryo reconstruction
1 Images
Immunophenotyping: Panel A FCS file(s)
6 Images

 Disease Models

Please visit the desktop version to see this section

 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Eye with optic nerve - developmental and structural abnormality Abca1tm1b(EUCOMM)Hmgu HET Early adult
Eye with optic nerve - hypoplasia Abca1tm1b(EUCOMM)Hmgu HET Early adult

 Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Abca1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Abca1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Abca1tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Abca1tm398(L1L2_Bact_P) Targeting vectors
Abca1tm398(L1L2_gt0) Targeting vectors
Abca1tm398(L1L2_st0) Targeting vectors