Genes Phenotypes

Gene: Abca1

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Name
ATP-binding cassette, sub-family A (ABC1), member 1
MGI ID
MGI:99607
Synonyms
ABC1
Viability
Homozygous - Lethal
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (205) All data table (703)
Expression & images (111) Disease models (0) Order (6)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal locomotor behavior Abca1tm1b(EUCOMM)Hmgu HET Early adult 6.22×10-05
abnormal embryo size Abca1tm1b(EUCOMM)Hmgu HET E18.5 0.00
preweaning lethality, complete penetrance Abca1tm1b(EUCOMM)Hmgu HOM Early adult 0.00
abnormal embryo size Abca1tm1b(EUCOMM)Hmgu HOM E18.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 3 No  (2/584)  (2/3)  Wholemount images
Aorta 3 No  (3/3)  Wholemount images
Bone 3 No  (3/3)  Wholemount images
Brain 3 No  (3/3)  Wholemount images
Brainstem 3 No  (3/3)  Wholemount images
Brown adipose tissue 3 No  (3/3)  Wholemount images
Cartilage tissue 3 No  (3/3)  Wholemount images
Cecum 3 No  (12/379) N/A
Cerebellum 3 No  (3/3)  Wholemount images
Cerebral cortex 3 No  (3/3)  Wholemount images
Esophagus 3 No  (7/415) N/A
Eye 3 No N/A
Gall bladder 3 No  (3/3)  Wholemount images
Heart 3 No  (3/3)  Wholemount images
Hippocampus 3 No  (3/3)  Wholemount images
Hypothalamus 3 No  (3/3)  Wholemount images
Kidney 3 No  (18/584)  (3/3)  Wholemount images
Large intestine 3 No  (10/584) N/A
Liver 3 No  (3/3)  Wholemount images
Lower urinary tract 3 No  (3/3)  Wholemount images
Lung 3 No  (3/3) N/A
Lymph node 3 No  (3/3) N/A
Mammary gland 3 No N/A
Olfactory lobe 3 No  (3/3)  Wholemount images
Oral epithelium 3 No  (3/3)  Wholemount images
Ovary 3 No  (1/584)  (1/3)  Wholemount images
Oviduct 3 No  (1/3)  Wholemount images
Pancreas 3 No  (5/584)  (3/3)  Wholemount images
Parathyroid gland 3 No N/A
Peripheral nervous system 3 No  (3/3)  Wholemount images
Peyer's patch 3 No N/A
Pituitary gland 3 No  (3/3)  Wholemount images
Prostate gland 3 No  (12/584)  (2/3)  Wholemount images
Skeletal muscle 3 No  (3/3)  Wholemount images
Skin 3 No  (3/3)  Wholemount images
Small intestine 3 No  (9/584) N/A
Spinal cord 3 No  (3/3)  Wholemount images
Spleen 3 No  (2/584) N/A
Stomach 3 No  (12/584)  (3/3)  Wholemount images
Striatum 3 No  (3/3)  Wholemount images
Testis 3 No  (2/584)  (2/3)  Wholemount images
Thymus 3 No N/A
Thyroid gland 3 No  (15/584)  (3/3)  Wholemount images
Trachea 3 No  (3/3)  Wholemount images
Trigeminal V nerve 3 No  (3/3)  Wholemount images
Uterus 3 No  (1/3)  Wholemount images
Vas deferens 3 No  (15/388)  (1/3)  Wholemount images
Vascular system 3 No N/A
White adipose tissue 3 No  (3/3)  Wholemount images
LacZ Wholemount Images
Unassigned Top Level MA (6)
adipose tissue (2)
Brown adipose tissue expression
MA:0000057
cardiovascular system (1)
Heart expression
Aorta expression
MA:0000072
MA:0000062
digestive system (5)
Liver expression
Gall Bladder expression
MA:0000358
MA:0000356
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (2)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
integumental system (2)
Skin expression
MA:0000151
musculoskeletal system (1)
Cartilage tissue expression
Skeletal Muscle expression
Bone expression
MA:0000104
MA:0003148
MA:0001459
nervous system (8)
Cerebral Cortex expression
Brain expression
Striatum expression
Hippocampus expression
Hypothalamus expression
Cerebellum expression
Brainstem expression
Olfactory Lobe expression
MA:0000185
MA:0000168
MA:0000891
MA:0000191
MA:0000173
MA:0000198
MA:0000169
MA:0002413
postnatal mouse (29)
Adrenal gland expression
MA:0000116
reproductive system (4)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
respiratory system (3)
Oral epithelium expression
MA:0000344
set of connective tissues (3)
Brown adipose tissue expression
MA:0000057
trunk (17)
Adrenal gland expression
MA:0000116
urinary system (4)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/57) N/A
Axial skeleton 2  (1/61) N/A
Brain 2  (6/504)  (2/3) N/A
Central nervous system ganglion 2  (1/70)  (1/3) N/A
Cranium 2  (1/61) N/A
Dorsal root ganglion 2  (1/57) N/A
Ear 2  (1/504) N/A
Embryo 2  (1/505)  (2/3) N/A
Outer ear 2  (1/66) N/A
Eye 2  (1/504) N/A
Femur pre-cartilage condensation 2  (1/52)  (2/3) N/A
Foot 2  (1/504)  (2/3) N/A
Forearm 2  (1/297) N/A
Forebrain 2  (1/504)  (2/3) N/A
Forelimb 2  (1/504)  (2/3) N/A
Fronto-nasal process 2  (1/58)  (2/3) N/A
Gut 2  (1/56) N/A
Hand 2  (1/503)  (2/3) N/A
Head 2  (5/504)  (2/3) N/A
Head mesenchyme 2  (1/57)  (2/3) N/A
Heart 2  (1/504) N/A
Heart ventricle 2  (1/57) N/A
Hindbrain 2  (6/504)  (2/3) N/A
Hindlimb 2  (1/503)  (2/3) N/A
Humerus pre-cartilage condensation 2  (1/61) N/A
Inner ear 2  (1/61) N/A
Intestine 2  (1/55) N/A
Liver 2  (1/504)  (2/3) N/A
Lower leg 2  (1/297) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504)  (1/3) N/A
Maxillary process 2  (1/504) N/A
Mesonephros of female 2  (1/52) N/A
Mesonephros of male 2  (1/52) N/A
Metanephros 2  (1/52) N/A
Midbrain 2  (1/504)  (2/3) N/A
Nasal septum 2  (1/57) N/A
Nose 2  (1/70) N/A
Notochord 2  (1/57) N/A
Oral cavity 2  (1/504)  (2/3) N/A
Outflow tract 2  (1/57) N/A
Pancreas 2  (1/52) N/A
Pericardium 2  (1/52)  (2/3) N/A
Pharynx 2  (1/52) N/A
Radius-ulna pre-cartilage condensation 2  (1/61)  (2/3) N/A
Rib pre-cartilage condensation 2  (1/54)  (2/3) N/A
Skeleton 2  (1/70) N/A
Skin 2  (1/504) N/A
Spinal cord 2  (1/69)  (2/3) N/A
Stomach 2  (1/52)  (2/3) N/A
Tail 2  (1/504)  (2/3) N/A
Tail somite 2  (1/504)  (2/3) N/A
Thoracic vertebral cartilage condensation 2  (1/52)  (2/3) N/A
Tongue 2  (1/52)  (2/3) N/A
Trachea 2  (1/56) N/A
Trunk mesenchyme 2  (1/57)  (2/3) N/A
Umbilical artery embryonic part 2  (1/57) N/A
Umbilical vein embryonic part 2  (1/57) N/A
Upper arm 2  (1/297) N/A
Upper leg 2  (1/297) N/A
Urinary system 2  (1/56) N/A
Vibrissa 2  (1/66) N/A

 Associated Images

X-ray: XRay Images Forepaw
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
Adult LacZ: LacZ Images Wholemount
35 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
Embryo LacZ: LacZ images wholemount
5 Images

 Disease Models

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MGI Allele Allele Type Produced
Abca1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Abca1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Abca1tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Abca1tm398(L1L2_Bact_P) Targeting vectors
Abca1tm398(L1L2_gt0) Targeting vectors
Abca1tm398(L1L2_st0) Targeting vectors