Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Hspa1b by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Primary Erythromelalgia | Hypothermia | ORPHA:90026 | |
Riboflavin Deficiency | Hypothermia | OMIM:615026 | |
2-Methylbutyryl-Coa Dehydrogenase Deficiency | Hypothermia | OMIM:610006 | |
Developmental And Epileptic Encephalopathy 78 | Hypothermia | OMIM:618557 | |
Spontaneous Periodic Hypothermia | Hypothermia | ORPHA:29822 | |
Coenzyme Q10 Deficiency, Primary, 5 | Hypothermia | OMIM:614654 | |
Mitochondrial Complex Iv Deficiency, Nuclear Type 13 | Hypothermia | OMIM:616501 | |
Idiopathic Congenital Hypothyroidism | Hypothermia | ORPHA:95717 | |
Sudden Infant Death-Dysgenesis Of The Testes Syndrome | Hypothermia | ORPHA:168593 | |
Mitochondrial Dna Depletion Syndrome 9 (Encephalomyopathic Type With Methylmalonic Aciduria) | Hypothermia | OMIM:245400 | |
Rigidity And Multifocal Seizure Syndrome, Lethal Neonatal | Hypothermia | OMIM:614498 | |
Congenital Hypothyroidism Due To Maternal Intake Of Antithyroid Drugs | Hypothermia | ORPHA:226313 | |
Meningococcal Meningitis | Fever, Hypothermia | ORPHA:33475 | |
Menkes Disease | Hypothermia | OMIM:309400 | |
Familial Thyroid Dyshormonogenesis | Hypothermia | ORPHA:95716 | |
Timothy Syndrome | Hypothermia | OMIM:601005 | |
Hypotonia, Hypoventilation, Impaired Intellectual Development, Dysautonomia, Epilepsy, And Eye Abnormalities | Fever, Abnormality of temperature regulation, Hypothermia | OMIM:618493 | |
Sudden Infant Death With Dysgenesis Of The Testes Syndrome | Hypothermia | OMIM:608800 | |
Carnitine-Acylcarnitine Translocase Deficiency | Cyanosis, Hypothermia | ORPHA:159 | |
Congenital Enterovirus Infection | Fever, Hypothermia | ORPHA:292 | |
Mitochondrial Complex Iii Deficiency, Nuclear Type 10 | Hypothermia | OMIM:618775 | |
Genetic Transient Congenital Hypothyroidism | Hypothermia | ORPHA:226316 | |
Very Long Chain Acyl-Coa Dehydrogenase Deficiency | Hypothermia | ORPHA:26793 | |
3-Hydroxy-3-Methylglutaric Aciduria | Fever, Hypothermia | ORPHA:20 | |
Combined Oxidative Phosphorylation Deficiency 37 | Hypothermia | OMIM:618329 | |
Mitochondrial Dna Depletion Syndrome 3 (Hepatocerebral Type) | Hypothermia | OMIM:251880 | |
Ethylene Glycol Poisoning | Cyanosis, Hypothermia | ORPHA:31826 | |
Hypothyroidism Due To Tsh Receptor Mutations | Hypothermia | ORPHA:90673 | |
Aromatic L-Amino Acid Decarboxylase Deficiency | Temperature instability, Intermittent hypothermia | OMIM:608643 | |
Dopamine Beta-Hydroxylase Deficiency | Hypothermia | ORPHA:230 | |
Tbck-Related Intellectual Disability Syndrome | Hypothermia | ORPHA:488632 | |
Orthostatic Hypotension 1 | Intermittent hypothermia | OMIM:223360 | |
Adult-Onset Autosomal Dominant Leukodystrophy | Temperature instability, Hypothermia | ORPHA:99027 | |
Alexander Disease | Hypothermia | ORPHA:58 | |
Neuroleptic Malignant Syndrome | Fever, Hypothermia | ORPHA:94093 | |
Car T Cell Therapy-Associated Cytokine Release Syndrome | Fever, Increased circulating interleukin 6 concentration, Increased circulating interferon-gamma ... | ORPHA:542323 | |
Isolated Thyroid-Stimulating Hormone Deficiency | Hypothermia | ORPHA:90674 | |
Mitochondrial Dna-Associated Leigh Syndrome | Fever, Hypothermia | ORPHA:255210 | |
Fatal Infantile Lactic Acidosis With Methylmalonic Aciduria | Hypothermia | ORPHA:17 | |
Methylmalonic Acidemia With Homocystinuria, Type Cblc | Hypothermia | ORPHA:79282 | |
Menkes Disease | Hypothermia | ORPHA:565 | |
Rapid-Onset Childhood Obesity-Hypothalamic Dysfunction-Hypoventilation-Autonomic Dysregulation Syndrome | Fever, Cyanosis, Hypothermia | ORPHA:293987 | |
Hypothyroidism Due To Deficient Transcription Factors Involved In Pituitary Development Or Function | Hypothermia | ORPHA:226307 | |
Marburg Hemorrhagic Fever | Fever, Increased circulating antibody level, Hypothermia | ORPHA:99826 | |
Occipital Horn Syndrome | Hypothermia | ORPHA:198 | |
Hypothyroidism, Congenital, Nongoitrous, 2 | Hypothermia | OMIM:218700 | |
Hereditary Sensory And Autonomic Neuropathy Type 4 | Recurrent fever, Hypothermia, Unexplained fevers | ORPHA:642 | |
Sarcoidosis | Fever, Hypothermia | ORPHA:797 | |
Pura-Related Severe Neonatal Hypotonia-Seizures-Encephalopathy Syndrome | Hypothermia | ORPHA:438213 | |
Aregenerative Anemia | Fever, Abnormality of interleukin secretion | ORPHA:101096 |
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