Arrb2 | arrestin, beta 2
Physiological systems
17 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological
15 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
47Embryo tissues
increased circulating alkaline phosphatase level | 1 supporting dataset | Arrb2tm1.1(KOMP)Vlcg | homozygote | Early adult | 1.33x10-16 | ||
increased circulating cholesterol level | 1 supporting dataset | Arrb2tm1.1(KOMP)Vlcg | homozygote | Early adult | 3.14x10-6 | ||
increased grip strength | 2 supporting datasets | Arrb2tm1.1(KOMP)Vlcg | homozygote | Early adult | 9.38x10-6 | ||
increased circulating HDL cholesterol level | 1 supporting dataset | Arrb2tm1.1(KOMP)Vlcg | homozygote | Early adult | 1.17x10-6 | ||
increased circulating phosphate level | 1 supporting dataset | Arrb2tm1.1(KOMP)Vlcg | homozygote | Early adult | 4.64x10-5 | ||
increased circulating free fatty acids level | 1 supporting dataset | Arrb2tm1.1(KOMP)Vlcg | heterozygote | Early adult | 2.22x10-6 |
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adrenal gland | heterozygote | Section images | 50% (1/2) | 0.7% (4/570) |
aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
brain | heterozygote | Section images | 100% (2/2) | 0.86% (5/579) |
brainstem | heterozygote | Section images | 100% (2/2) | 0.41% (2/490) |
brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
cartilage tissue | heterozygote | Section images | 100% (2/2) | 0.22% (1/454) |
cerebellum | heterozygote | Section images | 100% (2/2) | 0.56% (3/532) |
cerebral cortex | heterozygote | Section images | 100% (2/2) | 0.41% (2/491) |
epididymis | heterozygote | n/a | 0% (0/1) | 87.5% (21/24) |
esophagus | heterozygote | n/a | 0% (0/2) | 1.67% (7/419) |
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Arrb2.
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Arrb2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
Arrb2tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
Arrb2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Arrb2tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |