Gene: Arrb2

Name
arrestin, beta 2
MGI ID
MGI:99474
Synonyms
beta-arrestin-2 Arr3 beta-arrestin2 arrestin 3 beta arr2
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating phosphate level Arrb2tm1.1(KOMP)Vlcg HOM postnatal 8.49×10-06
increased circulating alkaline phosphatase level Arrb2tm1.1(KOMP)Vlcg HOM postnatal 8.45×10-17
increased circulating cholesterol level Arrb2tm1.1(KOMP)Vlcg HOM postnatal 3.11×10-05
increased circulating HDL cholesterol level Arrb2tm1.1(KOMP)Vlcg HOM postnatal 7.04×10-09
increased grip strength Arrb2tm1.1(KOMP)Vlcg HOM postnatal 2.99×10-06
thrombocytopenia Arrb2tm1.1(KOMP)Vlcg HOM postnatal 6.99×10-05
decreased total body fat amount Arrb2tm1.1(KOMP)Vlcg HOM postnatal 1.04×10-05

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (1/2) N/A
Aorta 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2) N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (1/2) N/A
Liver 2 No  (1/2) N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No  (1/2) N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Peripheral nervous system 2 No  (1/2) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (1/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (1/2) N/A
Stomach 2 No  (12/584)  (1/2) N/A
Striatum 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No  (2/2) N/A
Thymus 2 No  (1/2) N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (1/2) N/A
Urinary bladder 2 No N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (2/3) N/A
Central nervous system ganglion 1  (1/51)  (1/1) N/A
Dorsal root ganglion 1  (1/47)  (1/1) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/3)  Wholemount images
Eye 2  (1/485)  (1/3) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485)  (1/3) N/A
Forelimb 2  (1/485) N/A
Fronto-nasal process 1  (1/48) Image Only N/A
Hand 2  (1/485) N/A
Head 2  (5/485)  (2/3) N/A
Heart 2  (1/485)  (1/3) N/A
Hindbrain 2  (6/485)  (2/3) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485)  (1/3) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485)  (2/3) N/A
Nose 1  (1/51) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Tail 2  (1/485)  (1/3) N/A
Tail somite 2  (1/485)  (1/3) N/A

 Associated Images

Combined SHIRPA and Dysmorphology
6 Images
Electroretinography: Cone waveform (pdf format)
8 Images
Sleep Wake: Wake state (bmp file)
22 Images
Electroretinography: Rod waveform (pdf format)
8 Images
Embryo LacZ: LacZ images wholemount
12 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Arrb2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Arrb2tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Arrb2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter